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Log D 7.4 and plasma protein binding of synthetic cannabinoid receptor agonists and a comparison of experimental and predicted lipophilicity.

Autor: Brandon AM; Leverhulme Research Centre for Forensic Science, School of Science and Engineering, University of Dundee, Dundee, UK.; Newcastle University Centre for Cancer, Newcastle University, Newcastle upon Tyne, UK., Baginski SR; Leverhulme Research Centre for Forensic Science, School of Science and Engineering, University of Dundee, Dundee, UK., Peet C; Drug Discovery Unit, Wellcome Centre for Anti-Infectives Research, School of Life Sciences, University of Dundee, Dundee, UK.; Debiopharm, Lausanne, Switzerland., Dugard P; Leverhulme Research Centre for Forensic Science, School of Science and Engineering, University of Dundee, Dundee, UK., Green H; Department of Forensic Genetics and Forensic Toxicology, National Board of Forensic Medicine, Linköping, Sweden.; Division of Clinical Chemistry and Pharmacology, Department of Biomedical and Clinical Sciences, Faculty of Medicine and Health Sciences, Linköping University, Linköping, Sweden., Sutcliffe OB; Department of Natural Sciences, Manchester Metropolitan University, Manchester, UK., Daéid NN; Leverhulme Research Centre for Forensic Science, School of Science and Engineering, University of Dundee, Dundee, UK., Nisbet LA; Leverhulme Research Centre for Forensic Science, School of Science and Engineering, University of Dundee, Dundee, UK., Read KD; Drug Discovery Unit, Wellcome Centre for Anti-Infectives Research, School of Life Sciences, University of Dundee, Dundee, UK., McKenzie C; Leverhulme Research Centre for Forensic Science, School of Science and Engineering, University of Dundee, Dundee, UK.; Chiron AS, Trondheim, Norway.

Publikováno v: Drug testing and analysis [Drug Test Anal] 2024 Sep; Vol. 16 (9), pp. 1012-1025. Date of Electronic Publication: 2023 Dec 08.