Toxic iron species in lower-risk myelodysplastic syndrome patients : course of disease and effects on outcome

Autor: Hoeks, Marlijn, Bagguley, Tim, van Marrewijk, Corine, Smith, Alex, Bowen, David, Culligan, Dominic, Kolade, Seye, Symeonidis, Argiris, Garelius, Hege, Spanoudakis, Michail, Langemeijer, Saskia, Roelofs, Rian, Wiegerinck, Erwin, Tatic, Aurelia, Killick, Sally, Panagiotidis, Panagiotis, Stanca, Oana, Hellström-Lindberg, Eva, Cermak, Jaroslav, van der Klauw, Melanie, Wouters, Hanneke, van Kraaij, Marian, Blijlevens, Nicole, Swinkels, Dorine W., de Witte, Theo, Stauder, R., Walder, A., Pfeilstöcker, M., Schoenmetzler-Makrai, A., Burgstaller, S., Thaler, J., Mandac Rogulj, I., Krejci, M., Voglova, J., Rohon, P., Jonasova, A., Cermak, J., Mikulenkova, D., Hochova, I., Jensen, P. D., Holm, M. S., Kjeldsen, L., Dufva, I. H., Vestergaard, H., Re, D., Slama, B., Fenaux, P., Choufi, B., Cheze, S., Klepping, D., Salles, B., de Renzis, B., Willems, L., De Prost, D., Gutnecht, J., Courby, S., Siguret, V., Tertian, G., Pascal, L., Chaury, M., Wattel, E., Guerci, A., Legros, L., Itzykson, R., Ades, L., Isnard, F., Sanhes, L., Benramdane, R., Stamatoullas, A., Amé, S., Beyne-Rauzy, O., Gyan, E., Platzbecker, U., Badrakan, C., Germing, U., Lübbert, M., Schlenk, R., Kotsianidis, I., Tsatalas, C., Pappa, V., Galanopoulos, A., Michali, E., Panagiotidis, P., Viniou, N., Katsigiannis, A., Roussou, P., Terpos, E., Kostourou, A., Kartasis, Z., Pouli, A., Palla, K., Briasoulis, V., Hatzimichael, E., Vassilopoulos, G., Symeonidis, A., Kourakli, A., Zikos, P., Anagnostopoulos, A., Kotsopoulou, M., Megalakaki, K., Protopapa, M., Vlachaki, E., Konstantinidou, P., Stemer, G., Nemetz, A., Gotwin, U., Cohen, O., Koren, M., Levy, E., Greenbaum, U., Gino-Moor, S., Price, M., Ofran, Y., Winder, A., Goldshmidt, N., Elias, S., Sabag, R., Hellman, I., Ellis, M., Braester, A., Rosenbaum, H., Berdichevsky, S., Itzhaki, G., Wolaj, O., Yeganeh, S., Katz, O., Filanovsky, K., Dali, N., Mittelman, M., Malcovati, L., Fianchi, L., vd Loosdrecht, A., Matthijssen, V., Herbers, A., Pruijt, H., Aboosy, N., de Vries, F., Velders, G., Jacobs, E., Langemeijer, S., MacKenzie, M., Lensen, C., Kuijper, P., Madry, K., Camara, M., Almeida, A., Vulkan, G., Stanca Ciocan, O., Tatic, A., Savic, A., Pedro, C., Xicoy, B., Leiva, P., Munoz, J., Betes, V., Benavente, C., Lozano, M., Martinez, M., Iniesta, P., Bernal, T., Diez Campelo, M., Tormo, D., Andreu Lapiedra, R., Sanz, G., Hesse Sundin, E., Garelius, H., Karlsson, C., Antunovic, P., Jönsson, A., Brandefors, L., Nilsson, L., Kozlowski, P., Hellstrom-Lindberg, E., Grövdal, M., Larsson, K., Wallvik, J., Lorenz, F., Ejerblad, E., Culligan, D., Craddock, C., Kolade, S., Cahalin, P., Killick, S., Ackroyd, S., Wong, C., Warren, A., Drummond, M., Hall, C., Rothwell, K., Green, S., Ali, S., Bowen, D., Karakantza, M., Dennis, M., Jones, G., Parker, J., Bowen, A., Radia, R., Das-Gupta, E., Vyas, P., Nga, E., Creagh, D., Ashcroft, J., Mills, J., Bond, L.

Publikováno v: Hoeks, M, Bagguley, T, van Marrewijk, C, Smith, A, Bowen, D, Culligan, D, Kolade, S, Symeonidis, A, Garelius, H, Spanoudakis, M, Langemeijer, S, Roelofs, R, Wiegerinck, E, Tatic, A, Killick, S, Panagiotidis, P, Stanca, O, Hellström-Lindberg, E, Cermak, J, van der Klauw, M, Wouters, H, van Kraaij, M, Blijlevens, N, Swinkels, D W, de Witte, T, Stauder, R, Walder, A, Pfeilstöcker, M, Schoenmetzler-Makrai, A, Burgstaller, S, Thaler, J, Mandac Rogulj, I, Krejci, M, Voglova, J, Rohon, P, Jonasova, A, Cermak, J, Mikulenkova, D, Hochova, I, Jensen, P D, Holm, M S, Kjeldsen, L, Dufva, I H, Vestergaard, H, Re, D, Slama, B, Fenaux, P, Choufi, B, Cheze, S, Klepping, D, Salles, B, de Renzis, B, Willems, L, De Prost, D, Gutnecht, J, Courby, S, Siguret, V, Tertian, G, Pascal, L, Chaury, M, Wattel, E, Guerci, A, Legros, L, Itzykson, R, Ades, L, Isnard, F, Sanhes, L, Benramdane, R, Stamatoullas, A, Amé, S, Beyne-Rauzy, O, Gyan, E, Platzbecker, U, Badrakan, C, Germing, U, Lübbert, M, Schlenk, R, Kotsianidis, I, Tsatalas, C, Pappa, V, Galanopoulos, A, Michali, E, Panagiotidis, P, Viniou, N, Katsigiannis, A, Roussou, P, Terpos, E, Kostourou, A, Kartasis, Z, Pouli, A, Palla, K, Briasoulis, V, Hatzimichael, E, Vassilopoulos, G, Symeonidis, A, Kourakli, A, Zikos, P, Anagnostopoulos, A, Kotsopoulou, M, Megalakaki, K, Protopapa, M, Vlachaki, E, Konstantinidou, P, Stemer, G, Nemetz, A, Gotwin, U, Cohen, O, Koren, M, Levy, E, Greenbaum, U, Gino-Moor, S, Price, M, Ofran, Y, Winder, A, Goldshmidt, N, Elias, S, Sabag, R, Hellman, I, Ellis, M, Braester, A, Rosenbaum, H, Berdichevsky, S, Itzhaki, G, Wolaj, O, Yeganeh, S, Katz, O, Filanovsky, K, Dali, N, Mittelman, M, Malcovati, L, Fianchi, L, vd Loosdrecht, A, Matthijssen, V, Herbers, A, Pruijt, H, Aboosy, N, de Vries, F, Velders, G, Jacobs, E, Langemeijer, S, MacKenzie, M, Lensen, C, Kuijper, P, Madry, K, Camara, M, Almeida, A, Vulkan, G, Stanca Ciocan, O, Tatic, A, Savic, A, Pedro, C, Xicoy, B, Leiva, P, Munoz, J, Betes, V, Benavente, C, Lozano, M, Martinez, M, Iniesta, P, Bernal, T, Diez Campelo, M, Tormo, D, Andreu Lapiedra, R, Sanz, G, Hesse Sundin, E, Garelius, H, Karlsson, C, Antunovic, P, Jönsson, A, Brandefors, L, Nilsson, L, Kozlowski, P, Hellstrom-Lindberg, E, Grövdal, M, Larsson, K, Wallvik, J, Lorenz, F, Ejerblad, E, Culligan, D, Craddock, C, Kolade, S, Cahalin, P, Killick, S, Ackroyd, S, Wong, C, Warren, A, Drummond, M, Hall, C, Rothwell, K, Green, S, Ali, S, Karakantza, M, Dennis, M, Jones, G, Parker, J, Bowen, A, Radia, R, Das-Gupta, E, Vyas, P, Nga, E, Creagh, D, Ashcroft, J, Mills, J, Bond, L & the EUMDS Registry Participants 2021, ' Toxic iron species in lower-risk myelodysplastic syndrome patients : course of disease and effects on outcome ', Leukemia, vol. 35, no. 6, pp. 1745-1750 . https://doi.org/10.1038/s41375-020-01022-2
on behalf of the EUMDS Registry Participants 2021, ' Toxic iron species in lower-risk myelodysplastic syndrome patients: course of disease and effects on outcome ', Leukemia, vol. 35, no. 6, pp. 1745-1750 . https://doi.org/10.1038/s41375-020-01022-2
Hoeks, M, Bagguley, T, van Marrewijk, C, Smith, A, Bowen, D, Culligan, D, Kolade, S, Symeonidis, A, Garelius, H, Spanoudakis, M, Langemeijer, S, Roelofs, R, Wiegerinck, E, Tatic, A, Killick, S, Panagiotidis, P, Stanca, O, Hellström-Lindberg, E, Cermak, J, van der Klauw, M, Wouters, H, van Kraaij, M, Blijlevens, N, Swinkels, D W, de Witte, T, on behalf of the EUMDS Registry Participants & Vestergaard, H 2021, ' Toxic iron species in lower-risk myelodysplastic syndrome patients : course of disease and effects on outcome ', Leukemia, vol. 35, no. 6, pp. 1745-1750 . https://doi.org/10.1038/s41375-020-01022-2
Leukemia, 35, 1745-1750
Leukemia, 35, 1745-1750. Nature Publishing Group
Leukemia, 35(6), 1745-1750. Nature Publishing Group
Leukemia, 35, 6, pp. 1745-1750
Leukemia

Red blood cell transfusions (RBCT) remain the cornerstone of supportive care in lower-risk myelodysplastic syndrome (LRMDS) [1]. Transfusion dependency in LRMDS patients is associated with inferior outcomes, mainly attributed to severe bone marrow fa

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https://eprints.whiterose.ac.uk/165856/1/s41375_020_01022_2.pdf

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Labile Plasma Iron (LPI) Is a Clinical Indicator of Overt Iron Overload in Patients with Lower-Risk Myelodysplastic Syndromes (MDS) from the European Leukemianet MDS Registry

Autor: De Swart, Louise Reiniers, Chloe Bagguley, Tim Bowen, David and Cermak, Jaroslav Hellstrom-Lindberg, Eva Tatic, Aurelia and Symeonidis, Argiris Huls, Gerwin Panagiotidis, Panagiotis and Garelius, Hege Culligan, Dominic Krejci, Marta van Marrewijk, Corine Droste, Jackie Smith, Alexandra Swinkels, Dorine W. de Witte, Theo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______2127::cec03bebec1f371abd4a7230109373e0
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3168020

Elevated Labile Plasma Iron Levels (LPI) and Increased Oxidative Stress Are Associated with Red Blood Cell Transfusions in Patients with Lower-Risk Myelodysplastic Syndromes (MDS) Subtitle: from the European Leukemianet MDS Registry

Autor: Hoeks, Marlijn ^*, Langemeijer, Saskia ^*, De Swart, Louise ^*, Bagguley, Tim ^*, van Marrewijk, Corine ^*, Bowen, David ^*, Cermak, Jaroslav, Hellstrom-Lindberg, Eva, Tatic, Aurelia ^*, Symeonidis, Argiris, Van Kraaij, Marian G.J. ^*, Panagiotidis, Panagiotis ^*, Garelius, Hege ^*, Culligan, Dominic J, Krejci, Marta ^*, Droste, Jackie ^*, Smith, Alexandra ^*, Swinkels, Dorine W., de Witte, Theo

Publikováno v: In Blood 2 December 2016 128(22):4327-4327

Toxic iron species in lower-risk myelodysplastic syndrome patients: course of disease and effects on outcome.

Autor: Hoeks M; Centre for Clinical Transfusion Research, Sanquin Research, Leiden, The Netherlands. marlijn.hoeks@radboudumc.nl.; Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, The Netherlands. marlijn.hoeks@radboudumc.nl.; Department of Hematology, Radboud University Medical Center, Nijmegen, The Netherlands. marlijn.hoeks@radboudumc.nl., Bagguley T; Epidemiology and Cancer Statistics Group, University of York, York, UK., van Marrewijk C; Department of Hematology, Radboud University Medical Center, Nijmegen, The Netherlands., Smith A; Epidemiology and Cancer Statistics Group, University of York, York, UK., Bowen D; St. James's Institute of Oncology, Leeds Teaching Hospitals, Leeds, UK., Culligan D; Department of Hematology, Aberdeen Royal Infirmary, Aberdeen, UK., Kolade S; Department of Hematology, Blackpool Victoria Hospital, Blackpool, Lancashire, UK., Symeonidis A; Department of Medicine, Division of Hematology, University of Patras Medical School, Patras, Greece., Garelius H; Department of Medicine, Sect. of Hematology and Coagulation, Sahlgrenska University Hospital, Göteborg, Sweden., Spanoudakis M; Department of Hematology, Airedale NHS Trust, Airdale, UK.; Department of Haematology, Warrington and Halton Teaching Hospitals NHS foundation Trust, Cheshire, UK., Langemeijer S; Department of Hematology, Radboud University Medical Center, Nijmegen, The Netherlands., Roelofs R; Department of Laboratory Medicine, Hepcidinanalysis.com, and Radboudumc Expertise Center for Iron Disorders, Radboud University Medical Center, Nijmegen, The Netherlands., Wiegerinck E; Department of Laboratory Medicine, Hepcidinanalysis.com, and Radboudumc Expertise Center for Iron Disorders, Radboud University Medical Center, Nijmegen, The Netherlands., Tatic A; Center of Hematology and Bone Marrow Transplantation, Fundeni Clinical Institute, Bucharest, Romania., Killick S; Department of Hematology, Royal Bournemouth Hospital, Bournemouth, UK., Panagiotidis P; Department of Haematology, 1st Department of Propedeutic Internal Medicine, National and Kapodistrian University of Athens, Medical School, Laikon General Hospital, Athens, Greece., Stanca O; Department of Hematology, Coltea Clinical Hospital, Bucharest, Romania., Hellström-Lindberg E; Department of Medicine, Division of Hematology, Karolinska Institutet, Stockholm, Sweden., Cermak J; Department of Clinical Hematology, Institute of Hematology and Blood Transfusion, Praha, Czech Republic., van der Klauw M; Department of Endocrinology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands., Wouters H; Department of Endocrinology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands., van Kraaij M; Department of Hematology, Radboud University Medical Center, Nijmegen, The Netherlands., Blijlevens N; Department of Hematology, Radboud University Medical Center, Nijmegen, The Netherlands., Swinkels DW; Department of Laboratory Medicine, Hepcidinanalysis.com, and Radboudumc Expertise Center for Iron Disorders, Radboud University Medical Center, Nijmegen, The Netherlands., de Witte T; Nijmegen Center for Molecular Life Sciences, Department of Tumor Immunology, Radboud University Medical Center, Nijmegen, The Netherlands.

Publikováno v: Leukemia [Leukemia] 2021 Jun; Vol. 35 (6), pp. 1745-1750. Date of Electronic Publication: 2020 Sep 18.