MiR-214-3p regulates Piezo1, lysyl oxidases and mitochondrial function in human cardiac fibroblasts.

Autor: Trevelyan CJ; Leeds Institute of Cardiovascular and Metabolic Medicine (LICAMM), School of Medicine, University of Leeds, Leeds LS2 9JT, UK., MacCannell ADV; Leeds Institute of Cardiovascular and Metabolic Medicine (LICAMM), School of Medicine, University of Leeds, Leeds LS2 9JT, UK., Stewart L; Leeds Institute of Cardiovascular and Metabolic Medicine (LICAMM), School of Medicine, University of Leeds, Leeds LS2 9JT, UK., Tarousa T; Leeds Institute of Cardiovascular and Metabolic Medicine (LICAMM), School of Medicine, University of Leeds, Leeds LS2 9JT, UK; School of Biomedical Sciences, Faculty of Biological Sciences, University of Leeds, Leeds LS2 9JT, UK., Taylor HA; Leeds Institute of Cardiovascular and Metabolic Medicine (LICAMM), School of Medicine, University of Leeds, Leeds LS2 9JT, UK., Murray M; Leeds Institute of Cardiovascular and Metabolic Medicine (LICAMM), School of Medicine, University of Leeds, Leeds LS2 9JT, UK., Bageghni SA; Leeds Institute of Cardiovascular and Metabolic Medicine (LICAMM), School of Medicine, University of Leeds, Leeds LS2 9JT, UK., Hemmings KE; Leeds Institute of Cardiovascular and Metabolic Medicine (LICAMM), School of Medicine, University of Leeds, Leeds LS2 9JT, UK., Drinkhill MJ; Leeds Institute of Cardiovascular and Metabolic Medicine (LICAMM), School of Medicine, University of Leeds, Leeds LS2 9JT, UK., Roberts LD; Leeds Institute of Cardiovascular and Metabolic Medicine (LICAMM), School of Medicine, University of Leeds, Leeds LS2 9JT, UK., Smith AJ; School of Biomedical Sciences, Faculty of Biological Sciences, University of Leeds, Leeds LS2 9JT, UK., Porter KE; Leeds Institute of Cardiovascular and Metabolic Medicine (LICAMM), School of Medicine, University of Leeds, Leeds LS2 9JT, UK., Forbes KA; Leeds Institute of Cardiovascular and Metabolic Medicine (LICAMM), School of Medicine, University of Leeds, Leeds LS2 9JT, UK., Turner NA; Leeds Institute of Cardiovascular and Metabolic Medicine (LICAMM), School of Medicine, University of Leeds, Leeds LS2 9JT, UK. Electronic address: n.a.turner@leeds.ac.uk.

Publikováno v: Matrix biology : journal of the International Society for Matrix Biology [Matrix Biol] 2024 Sep; Vol. 132, pp. 34-46. Date of Electronic Publication: 2024 Jun 25.

11β-HSD1 suppresses cardiac fibroblast CXCL2, CXCL5 and neutrophil recruitment to the heart post MI

Autor: Mylonas, KJ, Turner, NA, Bageghni, SA, Kenyon, CJ, White, CI, McGregor, K, Kimmitt, RA, Sulston, R, Kelly, V, Walker, BR, Porter, KE, Chapman, KE, Gray, GA

Publikováno v: Mylonas, K J, Turner, N A, Bageghni, S A, Kenyon, C J, White, C I, McGregor, K, Kimmitt, R A, Sulston, R, Kelly, V, Walker, B R, Porter, K E, Chapman, K E & Gray, G A 2017, ' 11β-HSD1 suppresses cardiac fibroblast CXCL2, CXCL5 and neutrophil recruitment to the heart post MI ', Journal of Endocrinology, vol. 233, no. 3, pp. 315-327 . https://doi.org/10.1530/JOE-16-0501

We have previously demonstrated that neutrophil recruitment to the heart following myocardial infarction (MI) is enhanced in mice lacking 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) that regenerates active glucocorticoid within cells from in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::307b88dea7b6dd3c1ff134b1a9496f49
https://www.pure.ed.ac.uk/ws/files/36518262/315.full.pdf

Fibroblast-specific deletion of interleukin-1 receptor-1 reduces adverse cardiac remodeling following myocardial infarction.

Autor: Bageghni SA; Discovery and Translational Science Department, Leeds Institute of Cardiovascular and Metabolic Medicine, School of Medicine, University of Leeds, Leeds, United Kingdom., Hemmings KE; Discovery and Translational Science Department, Leeds Institute of Cardiovascular and Metabolic Medicine, School of Medicine, University of Leeds, Leeds, United Kingdom., Yuldasheva NY; Discovery and Translational Science Department, Leeds Institute of Cardiovascular and Metabolic Medicine, School of Medicine, University of Leeds, Leeds, United Kingdom., Maqbool A; Discovery and Translational Science Department, Leeds Institute of Cardiovascular and Metabolic Medicine, School of Medicine, University of Leeds, Leeds, United Kingdom., Gamboa-Esteves FO; Leeds Institute of Cancer and Pathology, Leeds Teaching Hospitals NHS Trust, Leeds, United Kingdom., Humphreys NE; Faculty of Biology, Medicine and Health, University of Manchester, Manchester, United Kingdom., Jackson MS; Faculty of Biology, Medicine and Health, University of Manchester, Manchester, United Kingdom., Denton CP; Institute of Immunity and Transplantation, Centre for Rheumatology and Connective Tissue Diseases, University College London and Royal Free Hospital, London, United Kingdom., Francis S; Department of Infection, Immunity & Cardiovascular Disease, Medical School, University of Sheffield, Sheffield, United Kingdom., Porter KE; Discovery and Translational Science Department, Leeds Institute of Cardiovascular and Metabolic Medicine, School of Medicine, University of Leeds, Leeds, United Kingdom., Ainscough JF; Discovery and Translational Science Department, Leeds Institute of Cardiovascular and Metabolic Medicine, School of Medicine, University of Leeds, Leeds, United Kingdom., Pinteaux E; Faculty of Biology, Medicine and Health, University of Manchester, Manchester, United Kingdom., Drinkhill MJ; Discovery and Translational Science Department, Leeds Institute of Cardiovascular and Metabolic Medicine, School of Medicine, University of Leeds, Leeds, United Kingdom., Turner NA; Discovery and Translational Science Department, Leeds Institute of Cardiovascular and Metabolic Medicine, School of Medicine, University of Leeds, Leeds, United Kingdom.

Publikováno v: JCI insight [JCI Insight] 2019 Aug 08; Vol. 5. Date of Electronic Publication: 2019 Aug 08.

The nuclear matrix protein CIZ1 facilitates localization of Xist RNA to the inactive X-chromosome territory.

Autor: Ridings-Figueroa R; Department of Biology, University of York, York YO10 5DD, United Kingdom., Stewart ER; Department of Biology, University of York, York YO10 5DD, United Kingdom., Nesterova TB; Department of Biochemistry, University of Oxford, Oxford OX1 3QU, United Kingdom., Coker H; Department of Biochemistry, University of Oxford, Oxford OX1 3QU, United Kingdom., Pintacuda G; Department of Biochemistry, University of Oxford, Oxford OX1 3QU, United Kingdom., Godwin J; Department of Biochemistry, University of Oxford, Oxford OX1 3QU, United Kingdom., Wilson R; Department of Biology, University of York, York YO10 5DD, United Kingdom., Haslam A; Department of Biology, University of York, York YO10 5DD, United Kingdom., Lilley F; Department of Biology, University of York, York YO10 5DD, United Kingdom., Ruigrok R; Leeds Institute of Cardiovascular and Metabolic Medicine (LICAMM), University of Leeds, Leeds LS2 9JT, United Kingdom., Bageghni SA; Leeds Institute of Cardiovascular and Metabolic Medicine (LICAMM), University of Leeds, Leeds LS2 9JT, United Kingdom., Albadrani G; Leeds Institute of Cardiovascular and Metabolic Medicine (LICAMM), University of Leeds, Leeds LS2 9JT, United Kingdom.; Princess Nourah Bint Abdulrahman University (PNU), Riyadh, Kingdom of Saudi Arabia., Mansfield W; Stem Cell Institute, University of Cambridge, Cambridge CB2 1QR, United Kingdom., Roulson JA; Leeds Institute of Molecular Medicine (LIMM), University of Leeds, Leeds LS9 7TF, United Kingdom., Brockdorff N; Department of Biochemistry, University of Oxford, Oxford OX1 3QU, United Kingdom., Ainscough JFX; Department of Biology, University of York, York YO10 5DD, United Kingdom.; Leeds Institute of Cardiovascular and Metabolic Medicine (LICAMM), University of Leeds, Leeds LS2 9JT, United Kingdom., Coverley D; Department of Biology, University of York, York YO10 5DD, United Kingdom.

Publikováno v: Genes & development [Genes Dev] 2017 May 01; Vol. 31 (9), pp. 876-888. Date of Electronic Publication: 2017 May 25.

Investigating inherent functional differences between human cardiac fibroblasts cultured from nondiabetic and Type 2 diabetic donors.

Autor: Sedgwick B; Division of Cardiovascular and Diabetes Research, School of Medicine, University of Leeds, Leeds, UK., Riches K; Division of Cardiovascular and Diabetes Research, School of Medicine, University of Leeds, Leeds, UK; Multidisciplinary Cardiovascular Research Centre (MCRC), University of Leeds, Leeds, UK., Bageghni SA; Division of Cardiovascular and Diabetes Research, School of Medicine, University of Leeds, Leeds, UK; Multidisciplinary Cardiovascular Research Centre (MCRC), University of Leeds, Leeds, UK., O'Regan DJ; Multidisciplinary Cardiovascular Research Centre (MCRC), University of Leeds, Leeds, UK; Department of Cardiac Surgery, The Yorkshire Heart Centre, Leeds General Infirmary, Leeds, UK., Porter KE; Division of Cardiovascular and Diabetes Research, School of Medicine, University of Leeds, Leeds, UK; Multidisciplinary Cardiovascular Research Centre (MCRC), University of Leeds, Leeds, UK., Turner NA; Division of Cardiovascular and Diabetes Research, School of Medicine, University of Leeds, Leeds, UK; Multidisciplinary Cardiovascular Research Centre (MCRC), University of Leeds, Leeds, UK. Electronic address: n.a.turner@leeds.ac.uk.

Publikováno v: Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology [Cardiovasc Pathol] 2014 Jul-Aug; Vol. 23 (4), pp. 204-10. Date of Electronic Publication: 2014 Mar 26.