Výsledky vyhledávání

INHIBITION OF THROMBIN AND TRYPSIN BY TRIPEPTIDE ALDEHYDES

Autor: Sandor Bajusz, E. Széll, Barabás E, Bagdy D, P. Tolnay

Publikováno v: International Journal of Peptide and Protein Research. 12:217-221

Inhibitory effects of certain tripeptide aldehydes on both thrombin and trypsin have been found to be strongly substrate-dependent. These compounds should therefore be considered as inhibitors of the particular proteolytic reaction for which they had

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4294aafa405af36df7fb188dfbb74961
https://doi.org/10.1111/j.1399-3011.1978.tb02889.x

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Highly active and selective anticoagulants: D-Phe-Pro-Arg-H, a free tripeptide aldehyde prone to spontaneous inactivation, and its stable N-methyl derivative, D-MePhe-Pro-Arg-H

Autor: E. Széll, Barabás E, Gy. Horváth, Bagdy D, É. Tomori, Dioszegi M, Juhasz A, Bajusz S, Fittler Z, G. Szabó

Publikováno v: Journal of Medicinal Chemistry. 33:1729-1735

D-Phe-Pro-Arg-H sulfate (GYKI-14166) is a highly active and selective inhibitor of thrombin both in vitro and in vivo. Recent studies on the stability of D-Phe-Pro-Arg-H in neutral aqueous solution at higher temperature have revealed that it is trans

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d0445e8eed297f81121b6bbac26215f
https://doi.org/10.1021/jm00168a030

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Interaction of peptidyl arginine aldehydes with thrombin

Autor: E. Szell, Gy. Horváth, Bajusz S, Bagdy D, E. Barabas

Publikováno v: Peptides 1990 ISBN: 9789072199089
Peptides 1990

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c61cda3b95dde591deab9229114b8519
https://doi.org/10.1007/978-94-011-3034-9_323

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Pharmacodynamic effects and pharmacokinetics of D-MePhe-Pro-Arg-H.H2SO4 (GYKI-14766), a novel anticoagulant with antithrombotic properties

Autor: E. Széll, Barabás E, G. Szabó, Bagdy D, S. Bajusz

Publikováno v: European Journal of Pharmacology. 183:1835-1836

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::08092bc5cde5c554aca87c06a2234e17
https://doi.org/10.1016/0014-2999(90)92161-b

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Akademický článek

INHIBITION OF THROMBIN AND TRYPSIN BY TRIPEPTIDE ALDEHYDES.

Autor: Bajusz, S., Barabas, E., Tolnay, P., Szell, E., Bagdy, D.

Publikováno v: International Journal of Peptide & Protein Research; 1978, Vol. 12 Issue 4, p217-221, 5p

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Akademický článek

Beta-2-microglobulin-specific autoantibodies cause platelet aggregation and interfere with ADP-induced aggregation.

Autor: Falus, A., Merétey, Katalin, Bagdy, D., Diószegi, Marianna, Böhm, Ute, Csák, Éva, Bozsóky, S.

Publikováno v: Clinical & Experimental Immunology; Jan1982, Vol. 47 Issue 1, p103-109, 7p

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Akademický článek

Autor: Varga, E., Bagdy, D., Kesztyüs, L.

Publikováno v: Naunyn-Schmiedebergs Archiv für Experimentelle Pathologie und Pharmakologie; 1949, Vol. 207 Issue 1/2, p29-38, 10p

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CORRELATION BETWEEN THE ANTICOAGULANT AND ANTIPLATELET EFFECT OF D-PHE-PRO-ARG-H (RG-2958)

Autor: Bagdy D, E. Széll, L Sebestyén, Dioszegi M, Bajusz S, Zs Fittler, Barabás E

Publikováno v: XIth International Congress on Thrombosis and Haemostasis.

Anticoagulants usually have no antiplatelet effect and platelet function inhibitors do not interact with the coagulation factors. Since thrombin has a decisive role in thrombus formation (growth and stabilization), inhibitors of the effect of thrombi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a037e5f3ed8e460b7238773e841fba3f
https://doi.org/10.1055/s-0038-1643448

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