Zobrazeno 1 - 10
of 21
pro vyhledávání: '"BafA1, bafilomycin A1"'
Publikováno v:
The Journal of Biological Chemistry
Peptide conformation can change subject to environment cues. This concept also applies to many cationic amphipathic peptides (CAPs) known to have cell membrane lytic or penetrative activities. Well-conditioned CAPs can match the properties of the tar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11e5bcc1c77a58618c41d844f8e23287
https://doi.org/10.1016/j.jbc.2021.101364
https://doi.org/10.1016/j.jbc.2021.101364
Publikováno v:
The Journal of Biological Chemistry
Autophagosome–lysosome pathway (ALP) insufficiency has been suggested to play a critical role in the pathogenesis of cardiac hypertrophy. However, the mechanisms underlying ALP insufficiency remain largely unknown, and strategies to specifically ma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8c5ade638442a6ab31fc6f569d9e71c
https://doi.org/10.1016/j.jbc.2021.101189
https://doi.org/10.1016/j.jbc.2021.101189
Autor:
Nihal Altan-Bonnet, Hayley S. McLoughlin, Michael Schlame, Kirill Gorshkov, Wei Zheng, Ruth D. Azaria, Kimberly Lai, Yang Xu, Thaddeus J. Kunkel, Miriam Waghalter, Mark L. Schultz, Andrew P. Lieberman, Judith Storch, Maciej Jeziorek, Radek Dobrowolski, Bruce Nguyen Tran, Olga Ilnytska
Publikováno v:
The Journal of Biological Chemistry
Niemann–Pick C (NPC) is an autosomal recessive disorder characterized by mutations in the NPC1 or NPC2 genes encoding endolysosomal lipid transport proteins, leading to cholesterol accumulation and autophagy dysfunction. We have previously shown th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e618060edf1f1a6e72ee553566ccb780
https://doi.org/10.1016/j.jbc.2021.100813
https://doi.org/10.1016/j.jbc.2021.100813
Autor:
Elisabeth Sehn, Christian Behl, Christof Hiebel, Franz H. Grus, Vanessa Felzen, Uwe Wolfrum, Caroline Manicam, Natarajan Perumal, Debapriya Chakraborty, Elisabeth Stürner
Publikováno v:
Redox Biology
Redox Biology, Vol 24, Iss, Pp-(2019)
Redox Biology, Vol 24, Iss, Pp-(2019)
Oxidative stress and a disturbed cellular protein homeostasis (proteostasis) belong to the most important hallmarks of aging and of neurodegenerative disorders. The proteasomal and autophagic-lysosomal degradation pathways are key measures to maintai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15cc330b09215555a3158f06dbb32cb3
http://europepmc.org/articles/PMC6454062
http://europepmc.org/articles/PMC6454062
Publikováno v:
Autophagy
The PKA-CREB signaling pathway is involved in many cellular processes including autophagy. Recent studies demonstrated that PKA-CREB inhibits autophagy in yeast; however, the role of PKA-CREB signaling in mammalian cell autophagy has not been fully c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4403d335f4e8a9f2effb729904111bb8
http://europepmc.org/articles/PMC4509440
http://europepmc.org/articles/PMC4509440
Autor:
Brandstaetter, Hemma, Kishi-Itakura, Chieko, Tumbarello, David A, Manstein, Dietmar J, Buss, Folma
MYO1C, a single-headed class I myosin, associates with cholesterol-enriched lipid rafts and facilitates their recycling from intracellular compartments to the cell surface. Absence of functional MYO1C disturbs the cellular distribution of lipid rafts
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::17ba0c4866d3ae1f98f0a38a6a035180
https://eprints.soton.ac.uk/373994/
https://eprints.soton.ac.uk/373994/
Autor:
Hemma, Brandstaetter, Chieko, Kishi-Itakura, David A, Tumbarello, Dietmar J, Manstein, Folma, Buss
Publikováno v:
Autophagy
MYO1C, a single-headed class I myosin, associates with cholesterol-enriched lipid rafts and facilitates their recycling from intracellular compartments to the cell surface. Absence of functional MYO1C disturbs the cellular distribution of lipid rafts
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::81bb8beaead803791b818a5bebbd022c
https://pubmed.ncbi.nlm.nih.gov/25551774
https://pubmed.ncbi.nlm.nih.gov/25551774
Publikováno v:
Autophagy
BECN1/Beclin 1 is regarded as a critical component in the class III phosphatidylinositol 3-kinase (PtdIns3K) complex to trigger autophagy in mammalian cells. Despite its significant role in a number of cellular and physiological processes, the exact
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3847484241c769ed5c27bc9c14cfb36a
Publikováno v:
Bioscience Reports
Bioscience Reports, Vol 34, Iss 4, p e00117 (2014)
Bioscience Reports, Vol 34, Iss 4, p e00117 (2014)
STBD1 (starch-binding domain-containing protein 1) belongs to the CBM20 (family 20 carbohydrate binding module) group of proteins, and is implicated in glycogen metabolism and autophagy. However, very little is known about its regulation or interacti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe254ea7a2830701d36301b2e23ff3c8
http://europepmc.org/articles/PMC4076837
http://europepmc.org/articles/PMC4076837
Autor:
Melland-Smith M; a The Lunenfeld-Tanenbaum Research Institute; Mount Sinai Hospital ; Toronto , ON Canada., Ermini L, Chauvin S, Craig-Barnes H, Tagliaferro A, Todros T, Post M, Caniggia I
Publikováno v:
Autophagy [Autophagy] 2015 Apr 03; Vol. 11 (4), pp. 653-69.