Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Baerin Houghton"'
Autor:
Graham Cohen, Bernardo Rapoport, Sze W Chan, Paul Ruff, Ana Arance, Karmele Mujika Eizmendi, Baerin Houghton, Michael P Brown, Robert M Zielinski, Eva Muñoz Couselo, Megan Lyle, James R Anderson, Lokesh Jain, Dinesh de Alwis, Mallika Lala, Omobolaji Akala, Elliot Chartash, Conrad Jacobs
Publikováno v:
PLoS ONE, Vol 19, Iss 11, p e0309778 (2024)
Intravenous pembrolizumab 400 mg every 6 weeks was approved across tumor types based on pharmacokinetic modeling, which showed exposures consistent with previous standard dosing of 200 mg or 2 mg/kg every 3 weeks, and early results of cohort B of the
Externí odkaz:
https://doaj.org/article/160650ac9b154127a4ad18e487432848
Autor:
Dariusz M. Kowalski, Keunchil Park, Vishal Boolell, Salma K. Jabbour, Steven M. Keller, Valeriy Breder, Amy Sanford, Nikolaj Frost, Baerin Houghton, A. Samkari, Martin Reck, Ki Hyeong Lee, Noemi Reguart, Hong Liu, Alex Martinez-Marti, Takefumi Komiya, Theodore Pollock, Jean Baptiste Paoli, Sufia Safina, Evgeny Levchenko
Publikováno v:
JAMA Oncol
IMPORTANCE: Administration of pembrolizumab plus concurrent chemoradiation therapy (cCRT) may provide treatment benefit to patients with locally advanced, stage III non–small cell lung cancer (NSCLC). OBJECTIVE: To evaluate treatment outcomes and s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7609733e2099c09e1daaebba833b59f
https://europepmc.org/articles/PMC8446818/
https://europepmc.org/articles/PMC8446818/
Autor:
Martin Reck, Ki Hyeong Lee, Nicolaj Frost, Valeriy Vladimirovich Breder, Dariusz Kowalski, Evgeny Levchenko, Noemi Reguart, Alex Martinez-Marti, Baerin Houghton, Jean-Baptiste Paoli, Sufiia Safina, Takefumi Komiya, Amy Sanford, Hong Liu, Andrew J. Song, Steven M. Keller, Salma K. Jabbour
Publikováno v:
Journal of Clinical Oncology. 40:8508-8508
8508 Background: Primary analysis (database cutoff, Oct 28, 2020) of the global KEYNOTE-799 study (NCT03631784) in patients (pts) with unresectable, locally advanced stage III NSCLC, showed that pembrolizumab (pembro; anti–PD-1) plus cCRT resulted
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::685302e07afefd4be69465c3ab08e1a4
https://doi.org/10.1200/jco.2022.40.16_suppl.8508
https://doi.org/10.1200/jco.2022.40.16_suppl.8508
Autor:
Salma K. Jabbour, Baerin Houghton, Andrew George Robinson, Xavier Quantin, Thomas Wehler, Dariusz Kowalski, Myung-Ju Ahn, Mustafa Erman, Giuseppe Giaccone, Hossein Borghaei, Jessica McLean, Yan Xu, Fabricio Souza, Georg Pall
Publikováno v:
Journal of Clinical Oncology. 40:TPS8597-TPS8597
TPS8597 Background: Anti–PD-(L)1-directed therapy following radiotherapy or following concurrent chemoradiation is associated with significantly longer PFS and OS in patients with advanced or metastatic NSCLC, including those with locally advanced
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::65e1e5fa961f11af5814d159f1877694
https://doi.org/10.1200/jco.2022.40.16_suppl.tps8597
https://doi.org/10.1200/jco.2022.40.16_suppl.tps8597
Autor:
Delvys Rodriguez-Abreu, Bilal Piperdi, Luis Paz-Ares, Jianxin Lin, Takayasu Kurata, Shirish M. Gadgeel, Balazs Halmos, Baerin Houghton, Marina Chiara Garassino, Ying Cheng, M. Catherine Pietanza, Hossein Borghaei, Corey J. Langer
Publikováno v:
Cancer
Background Pembrolizumab plus platinum‐based chemotherapy has demonstrated improved clinical outcomes over chemotherapy alone in patients with previously untreated advanced/metastatic non–small cell lung cancer (NSCLC), regardless of tumor progra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da398adb2787fa3bcc2db943dfc67e66
https://pubmed.ncbi.nlm.nih.gov/32914866
https://pubmed.ncbi.nlm.nih.gov/32914866
Autor:
Baerin Houghton, Dariusz M. Kowalski, Issam Abdelkarim Alawin, Nicolaj Frost, Alex Martinez-Marti, Noemi Reguart, Amy Sanford, A. Samkari, Steven M. Keller, Jean-Baptiste Paoli, Vishal Boolell, Takefumi Komiya, Hong Liu, Salma K. Jabbour, Valeriy Breder, Sufia Safina, Ki Hyeong Lee, Evgeny Levchenko, Martin Reck, Keunchil Park
Publikováno v:
Journal of Clinical Oncology. 39:8512-8512
8512 Background: KEYNOTE-799 (NCT03631784) is an ongoing study of the anti‒PD-1 antibody pembrolizumab (pembro) plus concurrent chemoradiation therapy (cCRT) in patients (pts) with unresectable, locally advanced stage III NSCLC. Prior results from
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c0133c508b9768ca4161a2a73463f535
https://doi.org/10.1200/jco.2021.39.15_suppl.8512
https://doi.org/10.1200/jco.2021.39.15_suppl.8512
Autor:
Guy C. Toner, Howard Gurney, M. Rosenthal, Mark D. Chatfield, Peter Grimison, Baerin Houghton, Martin R. Stockler, Michael Friedlander, Felicia Roncolato, Damien Thomson
Publikováno v:
Internal Medicine Journal. 46:893-898
Background/AimThe utility of pulmonary function testing (PFT) to detect bleomycin-induced pneumonitis is controversial. We describe its impact on bleomycin dosing in a phase 2 trial of accelerated BEP (bleomycin, etoposide, cisplatin) for advanced ge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::72a78ed97edc3e9eede8cf555903e8a6
https://doi.org/10.1111/imj.13158
https://doi.org/10.1111/imj.13158
Autor:
Giuseppe Giaccone, Andrew G. Robinson, Hossein Borghaei, Jin Zhang, Xavier Quantin, Jessica McLean, Dariusz M. Kowalski, Roy H. Decker, Salma K. Jabbour, Baerin Houghton, Myung-Ju Ahn, Mustafa Erman, Fabricio Souza, T. Wehler
Publikováno v:
Cancer Research. 80:CT288-CT288
Background: Anti-PD-(L)1-directed therapy following radiotherapy or following concurrent chemoradiation is associated with significantly longer PFS and OS in patients with advanced or metastatic NSCLC, including those with locally advanced inoperable
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::55a953343210ea3d4f70661168b95b8a
https://doi.org/10.1158/1538-7445.am2020-ct288
https://doi.org/10.1158/1538-7445.am2020-ct288
Autor:
Guy C. Toner, Mark D. Chatfield, Baerin Houghton, Ian D. Davis, Peter Grimison, Elizabeth Hovey, Jarad Martin, Martin R. Stockler
Publikováno v:
BJU International. 112:E35-E43
Objective To determine the patterns of management and surveillance imaging amongst medical oncologists in Australia for stage I testicular cancer during 2010. Methods We conducted a survey comprising 14 questions about the management strategy and sur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4621110d977310bcc8741f69142de23f
https://doi.org/10.1111/bju.12221
https://doi.org/10.1111/bju.12221
Autor:
Manish I. Patel, Baerin Houghton, Venu Chalasani, Martin R. Stockler, Peter Grimison, Dickon Hayne, Chris Brown, Ian D. Davis
Publikováno v:
BJU International. 111:977-983
What's known on the subject? and What does the study add? Non-muscle-invasive bladder cancer has a significant recurrence and progression rate despite transurethral resection. The current standard of care to lower the risk of recurrence and progressi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9f9344cec0b8f9eed56e7c58523f2a3f
https://doi.org/10.1111/j.1464-410x.2012.11390.x
https://doi.org/10.1111/j.1464-410x.2012.11390.x