Zobrazeno 1 - 10
of 68
pro vyhledávání: '"Baeocystin"'
Akademický článek
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Autor:
Klára Gotvaldová, Jan Borovička, Kateřina Hájková, Petra Cihlářová, Alan Rockefeller, Martin Kuchař
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 22, p 14068 (2022)
Since not only psilocybin (PSB) but also PSB-containing mushrooms are used for psychedelic therapy and microdosing, it is necessary to know their concentration variability in wild-grown mushrooms. This article aimed to determine the PSB, psilocin (PS
Externí odkaz:
https://doaj.org/article/5840f726615d4a77bf87b496fcd88c02
Akademický článek
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Autor:
Sandoval, Oscar
Clinical trials on the use of psilocybin to treat depression are promising but are confounded by the presence of hallucinations which may not be necessary for effectiveness. Preliminary data suggests that when administered to rats, related tryptamine
Autor:
McKinney, Madeline Gray
Clinical evaluation of psilocybin, a hallucinogen found in “magic mushrooms,” as treatment for severe depression and addiction is ongoing. Our enzymatic pathway to production of psilocybin involves norbaeocystin methyltransferase (PsiM), responsi
Autor:
Adam L. Halberstadt, Robert B. Kargbo, Alexander M. Sherwood, Poncho Meisenheimer, Kristi W. Kaylo, Adam K. Klein, John D. McCorvy
Publikováno v:
Journal of Natural Products. 83:461-467
A general synthetic method was developed to access known tryptamine natural products present in psilocybin-producing mushrooms. In vitro and in vivo experiments were then conducted to inform speculations on the psychoactive properties, or lack thereo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa9de7705e48582ab0e906cd5e38ec5c
https://doi.org/10.1021/acs.jnatprod.9b01061
https://doi.org/10.1021/acs.jnatprod.9b01061
Autor:
John D. Brinton, Chantal S. Monnier, Alexis L. Enacopol, Alexandra M. Adams, J. Andrew Jones, Nicholas A. Kaplan, Zhangyue Wei, Theresa Ramelot
Publikováno v:
Metabolic Engineering. 56:111-119
Psilocybin, the prodrug of the psychoactive molecule psilocin, has demonstrated promising results in clinical trials for the treatment of addiction, depression, and post-traumatic stress disorder. The development of a psilocybin production platform i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db9436389012def2794408337c636e25
https://doi.org/10.1016/j.ymben.2019.09.009
https://doi.org/10.1016/j.ymben.2019.09.009
Akademický článek
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The Psilocybe genus is well known for the synthesis of valuable psychoactive compounds such as Psilocybin, Psilocin, Baeocystin and Aeruginascin. The ubiquity of Psilocybin synthesis in Psilocybe has been attributed to a horizontal gene transfer mech
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a12fbc672579954d9a8550f8e2902985
Autor:
Felix Blei, Janis Fricke, Andreas Naschberger, Andrew Orry, Alexander M. Sherwood, Bernhard Rupp, Robert B. Kargbo, Dirk Hoffmeister
Publikováno v:
ChemBioChem. 20:2824-2829
Psilocybin and its direct precursor baeocystin are indole alkaloids of psychotropic Psilocybe mushrooms. The pharmaceutical interest in psilocybin as a treatment option against depression and anxiety is currently being investigated in advanced clinic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f45d771e14bb4b814f16ad9920ae021
https://doi.org/10.1002/cbic.201900358
https://doi.org/10.1002/cbic.201900358