A second space age spanning omics, platforms and medicine across orbits.

Autor: Mason CE; Department of Physiology and Biophysics and Tri-Institutional Computational Biology and Medicine Program, Weill Cornell Medicine, New York, NY, USA. chm2042@med.cornell.edu.; The WorldQuant Initiative for Quantitative Prediction, New York, NY, USA. chm2042@med.cornell.edu., Green J; Metavisionairies, Oxford, UK., Adamopoulos KI; Blue Marble Space Institute of Science, Space Biosciences Division, NASA Ames Research Center, Moffett Field, CA, USA.; Biomedical Engineering Laboratory, School of Electrical and Computer Engineering, National University of Athens, Athens, Greece., Afshin EE; Department of Physiology and Biophysics and Tri-Institutional Computational Biology and Medicine Program, Weill Cornell Medicine, New York, NY, USA., Baechle JJ; Buck Artificial Intelligence Platform, Buck Institute for Research on Aging, Novato, CA, USA., Basner M; Unit for Experimental Psychiatry, Division of Sleep and Chronobiology, Department of Psychiatry, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA., Bailey SM; Department of Environmental and Radiological Health Sciences, Colorado State University, Fort Collins, CO, USA., Bielski L; Department of Physiology and Biophysics and Tri-Institutional Computational Biology and Medicine Program, Weill Cornell Medicine, New York, NY, USA., Borg J; Centre for Molecular Medicine and Biobanking, University of Malta, Msida, Malta.; Department of Applied Biomedical Science, Faculty of Health Sciences, University of Malta, Msida, Malta., Borg J; Centre for Molecular Medicine and Biobanking, University of Malta, Msida, Malta.; Department of Applied Biomedical Science, Faculty of Health Sciences, University of Malta, Msida, Malta., Broddrick JT; Space Biosciences Division, NASA Ames Research Center, Moffett Field, CA, USA., Burke M; Department of Physiology and Biophysics and Tri-Institutional Computational Biology and Medicine Program, Weill Cornell Medicine, New York, NY, USA.; Embry-Riddle Aeronautical University, Department of Human Factors and Behavioral Neurobiology, Daytona Beach, FL, USA., Caicedo A; Instituto de Investigaciones en Biomedicina iBioMed, Universidad San Francisco de Quito USFQ, Quito, Ecuador.; Escuela de Medicina, Colegio de Ciencias de la Salud COCSA, Universidad San Francisco de Quito USFQ, Quito, Ecuador.; Sistemas Médicos SIME, Universidad San Francisco de Quito USFQ, Quito, Ecuador.; Mito-Act Research Consortium, Quito, Ecuador., Castañeda V; Faculty of Medicine, Universidad de los Andes, Santiago, Chile.; IMPACT, Center of Interventional Medicine for Precision and Advanced Cellular Therapy, Santiago, Chile.; Molecular Biology and Bioinformatics Lab, Program in Molecular Biology and Bioinformatics, Center for Biomedical Research and Innovation (CIIB), Universidad de los Andes, Santiago, Chile., Chatterjee S; Southwest Research Institute, Boulder, CO, USA., Chin CR; Department of Physiology and Biophysics and Tri-Institutional Computational Biology and Medicine Program, Weill Cornell Medicine, New York, NY, USA., Church G; Harvard Medical School, Boston, MA, USA., Costes SV; Space Biosciences Division, NASA Ames Research Center, Moffett Field, CA, USA., De Vlaminck I; Department of Physiology and Biophysics and Tri-Institutional Computational Biology and Medicine Program, Weill Cornell Medicine, New York, NY, USA., Desai RI; Integrative Neurochemistry Laboratory, Behavioral Biology Program, Department of Psychiatry, Harvard Medical School, Belmont, MA, USA., Dhir R; Seed Health, Venice, CA, USA.; Swiss Institute of Allergy and Asthma Research (SIAF), University of Zurich, Davos, Switzerland., Diaz JE; Data Science Institute, School of Business, Universidad San Francisco de Quito USFQ, Quito, Ecuador., Etlin SM; Department of Astrobiology, Cornell University, New York, NY, USA., Feinstein Z; Department of Physiology and Biophysics and Tri-Institutional Computational Biology and Medicine Program, Weill Cornell Medicine, New York, NY, USA., Furman D; Buck Institute for Research on Aging, Novato, CA, USA.; Stanford 1000 Immunomes Project, Stanford University School of Medicine, Stanford, CA, USA.; Institute for Research in Translational Medicine, Universidad Austral, CONICET, Pilar, Argentina., Garcia-Medina JS; Department of Physiology and Biophysics and Tri-Institutional Computational Biology and Medicine Program, Weill Cornell Medicine, New York, NY, USA., Garrett-Bakelman F; Department of Physiology and Biophysics and Tri-Institutional Computational Biology and Medicine Program, Weill Cornell Medicine, New York, NY, USA., Giacomello S; Science for Life Laboratory, Department of Gene Technology, KTH Royal Institute of Technology, Stockholm, Sweden., Gupta A; ANYg Labs, San Diego, CA, USA., Hassanin A; Department of Medical Microbiology and Immunology, Faculty of Medicine, Zagazig University, Zagazig, Egypt., Houerbi N; Department of Physiology and Biophysics and Tri-Institutional Computational Biology and Medicine Program, Weill Cornell Medicine, New York, NY, USA., Irby I; School of Biological Sciences, Georgia Institute of Technology, Atlanta, GA, USA., Javorsky E; Wyss Institute for Biologically Inspired Engineering, Harvard University, Boston, MA, USA.; Future of Life Institute, Campbell, CA, USA., Jirak P; Paracelsus Medical University, Salzburg, Austria.; Department of Internal Medicine, Hospital Gmünd, Lower Austria, Austria., Jones CW; Unit for Experimental Psychiatry, Division of Sleep and Chronobiology, Department of Psychiatry, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA., Kamal KY; Redox Biology and Cell Signaling Laboratory, Department of Kinesiology and Sport Management, Texas A&M University, College Station, TX, USA.; Department of Kinesiology, Iowa State University, Ames, USA., Kangas BD; Behavioral Biology Program, Department of Psychiatry, Harvard Medical School, Belmont, MA, USA., Karouia F; Blue Marble Institute of Science, Exobiology Branch NASA Ames Research Center, Moffett Field, CA, USA.; Space Research Within Reach, San Francisco, CA, USA.; Center for Space Medicine, Baylor College of Medicine, Houston, TX, USA.; BioServe Space Technologies, Smead Aerospace Engineering Science Department, University of Colorado Boulder, Boulder, CO, USA., Kim J; Department of Physiology and Biophysics and Tri-Institutional Computational Biology and Medicine Program, Weill Cornell Medicine, New York, NY, USA., Kim JH; Redox Biology and Cell Signaling Laboratory, Department of Kinesiology and Sport Management, Texas A&M University, College Station, TX, USA., Kleinman AS; Department of Physiology and Biophysics and Tri-Institutional Computational Biology and Medicine Program, Weill Cornell Medicine, New York, NY, USA., Lam T; Jet Propulsion Laboratory, California Institute of Technology, Pasadena, CA, USA., Lawler JM; Redox Biology and Cell Signaling Laboratory, Department of Kinesiology and Sport Management, Texas A&M University, College Station, TX, USA., Lee JA; Space Biosciences Division, NASA Ames Research Center, Moffett Field, CA, USA., Limoli CL; Department of Radiation Oncology, University of California, Irvine, CA, USA., Lucaci A; Department of Physiology and Biophysics and Tri-Institutional Computational Biology and Medicine Program, Weill Cornell Medicine, New York, NY, USA., MacKay M; Department of Physiology and Biophysics and Tri-Institutional Computational Biology and Medicine Program, Weill Cornell Medicine, New York, NY, USA., McDonald JT; Department of Radiation Medicine, Georgetown University School of Medicine, Washington, D.C., USA., Melnick AM; Department of Physiology and Biophysics and Tri-Institutional Computational Biology and Medicine Program, Weill Cornell Medicine, New York, NY, USA., Meydan C; Department of Physiology and Biophysics and Tri-Institutional Computational Biology and Medicine Program, Weill Cornell Medicine, New York, NY, USA., Mieczkowski J; International Research Agenda 3P-Medicine Laboratory, Medical University of Gdansk, Gdansk, Poland., Muratani M; Department of Genome Biology, Faculty of Medicine, University of Tsukuba, Ibaraki, Japan., Najjar D; Department of Physiology and Biophysics and Tri-Institutional Computational Biology and Medicine Program, Weill Cornell Medicine, New York, NY, USA., Othman MA; Redox Biology and Cell Signaling Laboratory, Department of Kinesiology and Sport Management, Texas A&M University, College Station, TX, USA., Overbey EG; Department of Physiology and Biophysics and Tri-Institutional Computational Biology and Medicine Program, Weill Cornell Medicine, New York, NY, USA.; The HRH Prince Alwaleed Bin Talal Bin Abdulaziz Alsaud Institute for Computational Biomedicine, Weill Cornell Medicine, New York, NY, USA.; BioAstra, New York, NY, USA., Paar V; Department of Internal Medicine II, Division of Cardiology, Paracelsus Medical University, Salzburg, Austria., Park J; Department of Physiology and Biophysics and Tri-Institutional Computational Biology and Medicine Program, Weill Cornell Medicine, New York, NY, USA., Paul AM; Blue Marble Space Institute of Science, Space Biosciences Division, NASA Ames Research Center, Moffett Field, CA, USA.; Embry-Riddle Aeronautical University, Department of Human Factors and Behavioral Neurobiology, Daytona Beach, FL, USA., Perdyan A; International Research Agenda 3P-Medicine Laboratory, Medical University of Gdansk, Gdansk, Poland.; Department of Biology, Stanford University, Stanford, CA, USA., Proszynski J; Department of Physiology and Biophysics and Tri-Institutional Computational Biology and Medicine Program, Weill Cornell Medicine, New York, NY, USA., Reynolds RJ; University of Texas Medical Branch, Galveston, TX, USA.; KBR, Inc., Houston, TX, USA., Ronca AE; Space Biosciences Division, NASA Ames Research Center, Moffett Field, CA, USA.; Wake Forest Medical School, Dept of Obstetrics and Gynecology, Winston-Salem, NC, USA., Rubins K; NASA Johnson Space Center, Houston, TX, USA., Ryon KA; Department of Physiology and Biophysics and Tri-Institutional Computational Biology and Medicine Program, Weill Cornell Medicine, New York, NY, USA., Sanders LM; Blue Marble Space Institute of Science, Space Biosciences Division, NASA Ames Research Center, Moffett Field, CA, USA., Glowe PS; BioAstra, Los Angeles, CA, USA., Shevde Y; Ursa Biotechnology Corporation, Ursa Bio, New York, NY, USA., Schmidt MA; Sovaris Aerospace, Boulder, CO, USA., Scott RT; KBR, Space Biosciences Division, NASA Ames Research Center, Moffett Field, CA, USA., Shirah B; Department of Neuroscience, King Faisal Specialist Hospital and Research Centre, Jeddah, Saudi Arabia., Sienkiewicz K; Department of Physiology and Biophysics and Tri-Institutional Computational Biology and Medicine Program, Weill Cornell Medicine, New York, NY, USA., Sierra MA; Department of Physiology and Biophysics and Tri-Institutional Computational Biology and Medicine Program, Weill Cornell Medicine, New York, NY, USA., Siew K; London Tubular Centre, Department of Renal Medicine, University College London, London, UK., Theriot CA; University of Texas Medical Branch, Galveston, TX, USA., Tierney BT; Department of Physiology and Biophysics and Tri-Institutional Computational Biology and Medicine Program, Weill Cornell Medicine, New York, NY, USA., Venkateswaran K; Jet Propulsion Laboratory, California Institute of Technology, Pasadena, CA, USA., Hirschberg JW; Department of Physiology and Biophysics and Tri-Institutional Computational Biology and Medicine Program, Weill Cornell Medicine, New York, NY, USA., Walsh SB; London Tubular Centre, Department of Renal Medicine, University College London, London, UK., Walter C; Department of Physiology and Biophysics and Tri-Institutional Computational Biology and Medicine Program, Weill Cornell Medicine, New York, NY, USA., Winer DA; Buck Institute for Research on Aging, Novato, CA, USA.; Leonard Davis School of Gerontology, University of Southern California, Los Angeles, CA, USA.; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada.; Division of Cellular and Molecular Biology, Toronto General Hospital Research Institute (TGHRI), University Health Network, Toronto, Ontario, Canada.; Department of Immunology, University of Toronto, Toronto, Ontario, Canada., Yu M; Department of Pharmacology, University of Maryland School of Medicine, Baltimore, MD, USA.; Department of Stem Cell Biology and Regenerative Medicine, University of Southern California, Los Angeles, CA, USA., Zea L; Smead Aerospace Engineering Sciences Department, University of Colorado Boulder, Boulder, CO, USA.; Jaguar Space, LLC, Erie, CO, USA., Mateus J; Space Exploration Technologies Corporation (SpaceX), Hawthorne, CA, USA., Beheshti A; Blue Marble Space Institute of Science, Space Biosciences Division, NASA Ames Research Center, Moffett Field, CA, USA. abehesht@broadinstitute.org.; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA. abehesht@broadinstitute.org.

Publikováno v: Nature [Nature] 2024 Aug; Vol. 632 (8027), pp. 995-1008. Date of Electronic Publication: 2024 Jun 11.

Chronic inflammation and the hallmarks of aging.

Autor: Baechle JJ; Buck Artificial Intelligence Platform, the Buck Institute for Research on Aging, Novato, CA, USA., Chen N; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada; Division of Cellular & Molecular Biology, Diabetes Research Group, Toronto General Hospital Research Institute (TGHRI), University Health Network, Toronto, ON, Canada., Makhijani P; Buck Artificial Intelligence Platform, the Buck Institute for Research on Aging, Novato, CA, USA; Department of Immunology, Faculty of Medicine, University of Toronto, Toronto, ON, Canada., Winer S; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada., Furman D; Buck Artificial Intelligence Platform, the Buck Institute for Research on Aging, Novato, CA, USA; Stanford 1000 Immunomes Project, Stanford University School of Medicine, Stanford, CA, USA; Instituto de Investigaciones en Medicina Traslacional (IIMT), Universidad Austral, CONICET, Pilar, Argentina. Electronic address: DFurman@buckinstitute.org., Winer DA; Buck Artificial Intelligence Platform, the Buck Institute for Research on Aging, Novato, CA, USA; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada; Department of Immunology, Faculty of Medicine, University of Toronto, Toronto, ON, Canada; Division of Cellular & Molecular Biology, Diabetes Research Group, Toronto General Hospital Research Institute (TGHRI), University Health Network, Toronto, ON, Canada; Leonard Davis School of Gerontology, University of Southern California, Los Angeles, CA, USA. Electronic address: DWiner@buckinstitute.org.

Publikováno v: Molecular metabolism [Mol Metab] 2023 Aug; Vol. 74, pp. 101755. Date of Electronic Publication: 2023 Jun 15.

ASO Author Reflections: Clinical Predictors of Pseudohypoxia Cluster Type Pheochromocytomas.

Autor: Baechle JJ; School of Medicine, Meharry Medical College, Nashville, TN, USA., Smith PM; Division of Surgical Oncology and Endocrine Surgery, Department of Surgery, Vanderbilt University Medical Center, Nashville, TN, USA., Kiernan CM; Division of Surgical Oncology and Endocrine Surgery, Department of Surgery, Vanderbilt University Medical Center, Nashville, TN, USA. colleen.m.kiernan@vumc.org.

Publikováno v: Annals of surgical oncology [Ann Surg Oncol] 2022 Jun; Vol. 29 (6), pp. 3547-3548. Date of Electronic Publication: 2022 Apr 03.

Multiplatform computational analysis of mast cells in adrenocortical carcinoma tumor microenvironment.

Autor: Baechle JJ; School of Medicine, Meharry Medical College, Nashville, TN; Department of Surgery, Division of Surgical Oncology and Endocrine Surgery, Vanderbilt University Medical Center, Nashville, TN., Hanna DN; Department of Surgery, Division of Surgical Oncology and Endocrine Surgery, Vanderbilt University Medical Center, Nashville, TN., Sekhar KR; Department of Surgery, Division of Surgical Oncology and Endocrine Surgery, Vanderbilt University Medical Center, Nashville, TN., Rathmell JC; Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, TN., Rathmell WK; Department of Medicine, Vanderbilt University Medical Center, Nashville, TN., Baregamian N; Department of Surgery, Division of Surgical Oncology and Endocrine Surgery, Vanderbilt University Medical Center, Nashville, TN. Electronic address: naira.baregamian@vumc.org.

Publikováno v: Surgery [Surgery] 2022 Jan; Vol. 171 (1), pp. 111-118. Date of Electronic Publication: 2021 Jul 11.

Integrative computational immunogenomic profiling of cortisol-secreting adrenocortical carcinoma.

Autor: Baechle JJ; School of Medicine, Meharry Medical College, Nashville, TN, USA., Hanna DN; Division of Surgical Oncology & Endocrine Surgery, Department of Surgery, Vanderbilt University Medical Center, Nashville, TN, USA., Sekhar KR; Division of Surgical Oncology & Endocrine Surgery, Department of Surgery, Vanderbilt University Medical Center, Nashville, TN, USA., Rathmell JC; Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, TN, USA., Rathmell WK; Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA., Baregamian N; Division of Surgical Oncology & Endocrine Surgery, Department of Surgery, Vanderbilt University Medical Center, Nashville, TN, USA.

Publikováno v: Journal of cellular and molecular medicine [J Cell Mol Med] 2021 Nov; Vol. 25 (21), pp. 10061-10072. Date of Electronic Publication: 2021 Oct 19.