E2f8 mediates tumor suppression in postnatal liver development

Autor: Kent, Lindsey N., Rakijas, Jessica B., Pandit, Shusil K., Westendorp, Bart, Chen, Hui Zi, Huntington, Justin T., Tang, Xing, Bae, Sooin, Srivastava, Arunima, Senapati, Shantibhusan, Koivisto, Christopher, Martin, Chelsea K., Cuitino, Maria C., Perez, Miguel, Clouse, Julian M., Chokshi, Veda, Shinde, Neelam, Kladney, Raleigh, Sun, Daokun, Perez-Castro, Antonio, Matondo, Ramadhan B., Nantasanti, Sathidpak, Mokry, Michal, Huang, Kun, Machiraju, Raghu, Fernandez, Soledad, Rosol, Thomas J., Coppola, Vincenzo, Pohar, Kamal S., Pipas, James M., Schmidt, Carl R., De Bruin, Alain, Leone, Gustavo, LS Pathobiologie, dPB RMSC

Publikováno v: CLIN Journal, 126(8), 2955-2969. AMER SOC CLINICAL INVESTIGATION INC
Journal of Clinical Investigation, 126(8), 2955. The American Society for Clinical Investigation

E2F-mediated transcriptional repression of cell cycle-dependent gene expression is critical for the control of cellular proliferation, survival, and development. E2F signaling also interacts with transcriptional programs that are downstream of geneti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23a3863c6ee3289b54d8e3657c61caa0
https://doi.org/10.1172/jci85506

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RB1 deficiency in triple-negative breast cancer induces mitochondrial protein translation.

Autor: Jones, Robert A.¹, Robinson, Tyler J.¹, Liu, Jeff C.¹, Shrestha, Mariusz^1,2, Voisin, Veronique³, YoungJun Ju¹, Chung, Philip E. D.^1,2, Pellecchia, Giovanna², Fell, Victoria L.¹, SooIn Bae⁴, Muthuswamy, Lakshmi⁵, Datti, Alessandro^6,7, Egan, Sean E.^8,9, Zhe Jiang¹, Leone, Gustavo⁴, Bader, Gary D.^3,9, Schimmer, Aaron¹⁰, Zacksenhaus, Eldad^1,2,11 eldad.zacksenhaus@utoronto.ca, Ju, YoungJun (AUTHOR), Bae, SooIn (AUTHOR)

Publikováno v: Journal of Clinical Investigation. Oct2016, Vol. 126 Issue 10, p3739-3757. 19p. 1 Color Photograph, 2 Diagrams, 1 Chart, 7 Graphs.