Zobrazeno 1 - 10
of 1 674
pro vyhledávání: '"Badri N"'
Autor:
Tohid Siddiqui, Mehmet Ilyas Cosacak, Stanislava Popova, Prabesh Bhattarai, Elanur Yilmaz, Annie J. Lee, Yuhao Min, Xue Wang, Mariet Allen, Özkan İş, Zeynep Tansu Atasavum, Natalia Rodriguez-Muela, Badri N. Vardarajan, Delaney Flaherty, Andrew F. Teich, Ismael Santa-Maria, Uwe Freudenberg, Carsten Werner, Giuseppe Tosto, Richard Mayeux, Nilüfer Ertekin-Taner, Caghan Kizil
Publikováno v:
npj Regenerative Medicine, Vol 8, Iss 1, Pp 1-18 (2023)
Abstract Neurogenesis, crucial for brain resilience, is reduced in Alzheimer’s disease (AD) that induces astroglial reactivity at the expense of the pro-neurogenic potential, and restoring neurogenesis could counteract neurodegenerative pathology.
Externí odkaz:
https://doaj.org/article/bebfc2431c024aae887659ececd580cc
Autor:
Min Qiao, Annie J. Lee, Dolly Reyes‐Dumeyer, Giuseppe Tosto, Kelley Faber, Alison Goate, Alan Renton, Michael Chao, Brad Boeve, Carlos Cruchaga, Margaret Pericak‐Vance, Jonathan L. Haines, Roger Rosenberg, Debby Tsuang, Robert A. Sweet, David A. Bennett, Robert S. Wilson, Tatiana Foroud, Richard Mayeux, Badri N. Vardarajan
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 10, Iss 5, Pp 744-756 (2023)
Abstract Objective To compute penetrance and recurrence risk using a genome‐wide PRS (including and excluding the APOE region) in families with Alzheimer's disease. Methods Genotypes from the National Institute on Aging Late‐Onset Alzheimer's Dis
Externí odkaz:
https://doaj.org/article/ca34451dd2fe4c19b1a16a4280fe7a72
Autor:
Mitchell Brüderlin, Raphael Böhm, Firas Fadel, Sebastian Hiller, Tilman Schirmer, Badri N. Dubey
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Bacterial multi-step phospho-relays employ receiver domains that act as intermediaries in phosphoryl shuttling. Here, the authors show that such a domain does not experience structural changes upon pseudo-phosphorylation, in contrast to the well-stud
Externí odkaz:
https://doaj.org/article/a9345acbe52d46e8ae7fc5d82d05967e
Publikováno v:
PLoS ONE, Vol 18, Iss 11, p e0281919 (2023)
The present pilot study aims to investigate the diagnostic and prognostic efficacy of serum HSP90 beta in Head and Neck Squamous Cell Carcinoma (HNSCC) patients subjected to localized hyperthermia therapy (HT). Serum levels of HSP90 beta were measure
Externí odkaz:
https://doaj.org/article/c1b2b51042674660a66902677e8d8db1
Autor:
Andreas Kaczmarczyk, Antje M. Hempel, Christoph von Arx, Raphael Böhm, Badri N. Dubey, Jutta Nesper, Tilman Schirmer, Sebastian Hiller, Urs Jenal
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
Bacteria adapt their growth rate to their metabolic status and environmental conditions by modulating the length of their G1 period. Here the authors show that an increase in c-di-GMP concentration modulates the activity of kinase ShkA and transcript
Externí odkaz:
https://doaj.org/article/a8b0383615d04194986ba09c5f07fc8e
Publikováno v:
Journal of Radiation and Cancer Research, Vol 11, Iss 4, Pp 142-149 (2020)
Background: Targeted alpha therapy (TAT) is emerging as an effective treatment modality of cancer especially for micrometastasis, lymphoproliferative malignancies, and palliative approaches of bone cancer. Human blood lymphocytes may encounter alpha
Externí odkaz:
https://doaj.org/article/b5951f07149e4de78bc4da74e00a1710
This paper introduces a novel class of PICOD($t$) problems referred to as $g$-group complete-$S$ PICOD($t$) problems. It constructs a multi-stage achievability scheme to generate pliable index codes for group complete PICOD problems when $S = \{s\}$
Externí odkaz:
http://arxiv.org/abs/2405.07151
Publikováno v:
Symmetry, Vol 14, Iss 3, p 599 (2022)
There are a total of 64 possible multiplication rules that can be defined starting with the generalized imaginary units first introduced by Hamilton. Of these sixty-four choices, only eight lead to non-commutative division algebras: two are associate
Externí odkaz:
https://doaj.org/article/b73e1658c71a4a5d823b89ee4f70d0aa
Publikováno v:
Journal of Radiation and Cancer Research, Vol 9, Iss 4, Pp 165-176 (2018)
According to the World Health Organization (2016), chronic obstructive pulmonary disease (COPD) and lung cancer (along with trachea and bronchial cancers) are third and sixth among 10 top causes of death globally. The association between lung cancer
Externí odkaz:
https://doaj.org/article/2f6f2b901ce44e94967a13fed029d413
Transformers have revolutionized image modeling tasks with adaptations like DeIT, Swin, SVT, Biformer, STVit, and FDVIT. However, these models often face challenges with inductive bias and high quadratic complexity, making them less efficient for hig
Externí odkaz:
http://arxiv.org/abs/2403.18063