Výsledky vyhledávání - "Bader M Aljaeid"

Superiority of TPGS-loaded micelles in the brain delivery of vinpocetine via administration of thermosensitive intranasal gel

Autor: Bader M Aljaeid, Osama A. A. Ahmed, Tarek A. Ahmed, Khalid M. El-Say

Publikováno v: International Journal of Nanomedicine. 14:5555-5567

Background: Vinpocetine (VPN) is a synthetic derivative of the Vinca minor alkaloids. The drug is characterized by a short half-life, limited water solubility and high hepatic first-pass effect. The objective was to develop different lipid-based nano

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::278e88f31336bf51c0138addee8217f4
https://doi.org/10.2147/ijn.s213086

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Chitosan-TPP nanoparticles stabilized by poloxamer for controlling the release and enhancing the bioavailability of doxazosin mesylate: in vitro, and in vivo evaluation

Autor: Khaled M. Hosny, Bader M Aljaeid, Khalid M. El-Say

Publikováno v: Drug Development and Industrial Pharmacy. 45:1130-1139

Objective: Control the release and enhance the bioavailability of chitosan-doxazosin mesylate nanoparticles (DM-NPs). Significance: Improve DM bioavailability for the treatment of benign prostatic hyperplasia and hypertension. Methods: Plackett-Burma

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f397cba22405afca56c79fa56f27db5b
https://doi.org/10.1080/03639045.2019.1597105

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Optimization of the Conditions for Plasmid DNA Delivery and Transfection with Self-Assembled Hyaluronic Acid-Based Nanoparticles

Autor: Mansoor M. Amiji, Hibah M. Aldawsari, Harkiranpreet Kaur Dhaliwal, Nabil A. Alhakamy, Zainy Mohammad Banjar, Bader M Aljaeid

Publikováno v: Molecular Pharmaceutics. 16:128-140

Polymeric systems have been extensively studied as polyelectrolyte complexes to enhance the cellular delivery and transfection efficiency of genetic materials, such as plasmid DNA (pDNA). Here, self-assembled nanoparticles were formulated by complexa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::560427f99e5c7545fcf1c0596644f5dc
https://doi.org/10.1021/acs.molpharmaceut.8b00904

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Optimized vinpocetine-loaded vitamin E D-α-tocopherol polyethylene glycol 1000 succinate-alpha lipoic acid micelles as a potential transdermal drug delivery system: in vitro and ex vivo studies

Autor: Khalid M. El-Say, Osama A. A. Ahmed, Bader M Aljaeid, Shaimaa M Badr-Eldin, Tarek A. Ahmed

Publikováno v: International Journal of Nanomedicine

Osama AA Ahmed,1,2 Khalid M El-Say,1,3 Bader M Aljaeid,1 Shaimaa M Badr-Eldin,1,4 Tarek A Ahmed1,3 1Department of Pharmaceutics, Faculty of Pharmacy, King Abdulaziz University, Jeddah, Kingdom of Saudi Arabia; 2Department of Pharmaceutics and Industr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cbaca7c25c6473b58522ed4f81d3418b
https://doi.org/10.2147/ijn.s187470

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Tadalafil Transdermal Delivery with Alpha-lipoic Acid Self Nanoemulsion for Treatment of Erectile Dysfunction by Diabetes Mellitus

Autor: Usama A. Fahmy, Bader M Aljaeid

Publikováno v: International Journal of Pharmacology. 14:945-951

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e1bc7aba5b6bfbad3033d2852be9874f
https://doi.org/10.3923/ijp.2018.945.951

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Loading of Gentamicin and Alpha Lipoic Acid on a Biodegradable Polymer for More Effective and Less Nephrotoxic Formula

Autor: Bader M Aljaeid, Mohamed Ahmed El-Moselhy

Publikováno v: International Journal of Pharmacology. 14:796-801

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9318f07c35dff97b56b847c4de38de07
https://doi.org/10.3923/ijp.2018.796.801

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Development of a fluvastatin-loaded self-nanoemulsifying system to maximize therapeutic efficacy in human colorectal carcinoma cells

Autor: Khalid M. El-Say, Mahmoud A. Elfaky, Bader M Aljaeid, Usama A. Fahmy, Ohood A. Al-Shareef, Hibah M. Aldawsari

Publikováno v: Journal of Drug Delivery Science and Technology. 46:7-13

Self-nanoemulsifying delivery systems (SNEDs) are one of the most important approaches for increasing the solubilization and absorption of a drug. This study aimed to develop a system using fluvastatin (FLV) in SNEDs with minimum globule size to enha

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7e2ceb24ecbacb58c5b7811545fbc714
https://doi.org/10.1016/j.jddst.2018.04.015

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Fabrication and evaluation of Phytomenadione as a nanostructure lipid carrier for enhancement of bioavailability

Autor: Bader M Aljaeid, Khaled M. Hosny

Publikováno v: Pharmaceutical Development and Technology. 23:382-386

Owing to its limited aqueous solubility, Phytomenadione (vitamin K) undergoes a low bioavailability (50%) with a large inter-individual variability after oral administration. Therefore, the aim of this work was to incorporate vitamin K into nanostruc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01b4890f0a9bf37cd1d1f31bfd38982e
https://doi.org/10.1080/10837450.2017.1312440

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A potential in situ gel formulation loaded with novel fabricated poly(lactide-co-glycolide) nanoparticles for enhancing and sustaining the ophthalmic delivery of ketoconazole

Autor: Tarek A. Ahmed, Bader M Aljaeid

Publikováno v: International Journal of Nanomedicine

Tarek Abdelnapy Ahmed,1,2 Bader M Aljaeid1 1Department of Pharmaceutics, Faculty of Pharmacy, King Abdulaziz University, Jeddah, Kingdom of Saudi Arabia; 2Department of Pharmaceutics and Industrial Pharmacy, Faculty of Pharmacy, Al-Azhar University,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76fb1453a94762a9033e2373feb706cf
https://doi.org/10.2147/ijn.s131850

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