Synthesis and Biological Evaluation of (-) and (+)-Spiroleucettadine and Analogues.

Autor: Badart MP; Department of Chemistry, University of Otago, Dunedin, 9054, New Zealand., Barnes EM; Department of Chemistry, University of Otago, Dunedin, 9054, New Zealand., Cording AP; Department of Chemistry, University of Otago, Dunedin, 9054, New Zealand., Gilmer SCL; Department of Chemistry, University of Otago, Dunedin, 9054, New Zealand., Billinghurst ID; Department of Chemistry, University of Otago, Dunedin, 9054, New Zealand., Edupuganti VVSR; School of Pharmacy, University of Otago, Dunedin, 9054, New Zealand., Lessene G; ACRF Chemical Biology Division, The Walter and Eliza Hall Institute of Medical Research, 1G Royal Parade, Parkville, 3052, Australia.; Department of Medical Biology, The University of Melbourne, Parkville, VIC 3050, Australia.; Department of Pharmacology and Therapeutics, The University of Melbourne, Parkville, VIC 3050, Australia., Bland AR; Department of Pharmacology and Toxicology, University of Otago, Dunedin, 9054, New Zealand., Bower RL; Department of Pharmacology and Toxicology, University of Otago, Dunedin, 9054, New Zealand., Rana Z; Department of Pharmacology and Toxicology, University of Otago, Dunedin, 9054, New Zealand., Ferguson SA; Department of Microbiology and Immunology, University of Otago, Dunedin, 9054, New Zealand., Opel Reading HK; Department of Biochemistry, University of Otago, Dunedin, 9054, New Zealand., Cook GM; Department of Microbiology and Immunology, University of Otago, Dunedin, 9054, New Zealand., Rosengren RJ; Department of Pharmacology and Toxicology, University of Otago, Dunedin, 9054, New Zealand., Krause KL; Department of Biochemistry, University of Otago, Dunedin, 9054, New Zealand., Gamble AB; School of Pharmacy, University of Otago, Dunedin, 9054, New Zealand., Ashton JC; Department of Pharmacology and Toxicology, University of Otago, Dunedin, 9054, New Zealand., Hawkins BC; Department of Chemistry, University of Otago, Dunedin, 9054, New Zealand.

Publikováno v: ChemMedChem [ChemMedChem] 2021 Apr 20; Vol. 16 (8), pp. 1308-1315. Date of Electronic Publication: 2021 Jan 26.