Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Badar A. Usmani"'
Autor:
Anthony J. Turner, Yue Hong, Adrian Whitehouse, Stuart A Macnab, Louise A. Lambert, Badar A. Usmani
Publikováno v:
International Journal of Cancer. 129:586-598
The zinc metalloprotease, endothelin-converting enzyme-1 (ECE-1), which converts the mitogenic peptide endothelin-1 (ET-1) from its biologically inactive precursor big-ET-1, is commonly upregulated in prostate cancer (PC) cells. Consequently, we have
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0373ed82fea9793f0a65605144055db8
https://doi.org/10.1002/ijc.25719
https://doi.org/10.1002/ijc.25719
Publikováno v:
British Journal of Cancer
Cross-talk between tumour and stromal cells can profoundly influence cancer cell invasion by increasing the availability of mitogenic peptides such as endothelin-1 (ET-1). Endothelin-1 is elevated in men with metastatic prostate cancer (PC), and can
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::148c56a22c62549ee6d2a7c2806820c9
http://europepmc.org/articles/PMC2567069
http://europepmc.org/articles/PMC2567069
Autor:
Louise A, Dawson, Badar A, Usmani
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 439
Small interfering RNAs (siRNAs) have been widely exploited for nucleotide-sequence-specific posttranscriptional gene silencing, as a tool to investigate gene function in eukaryotes, and they hold promise as potential therapeutic agents. Conventionall
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::de2993ec67fee17ef0c6f105b17b49bf
https://pubmed.ncbi.nlm.nih.gov/18370118
https://pubmed.ncbi.nlm.nih.gov/18370118
Autor:
Badar A. Usmani, Louise A. Dawson
Publikováno v:
Methods in Molecular Biology ISBN: 9781588298713
Small interfering RNAs (siRNAs) have been widely exploited for nucleotide-sequence-specific posttranscriptional gene silencing, as a tool to investigate gene function in eukaryotes, and they hold promise as potential therapeutic agents. Conventionall
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::002b926d7cc7e1c4a300d46f3a85acf7
https://doi.org/10.1007/978-1-59745-188-8_27
https://doi.org/10.1007/978-1-59745-188-8_27
Publikováno v:
Experimental biology and medicine (Maywood, N.J.). 231(6)
Endothelin (ET)-1 can influence cancer invasion and metastasis by exerting an autocrine (epithelial) or paracrine (stromal) influence on growth. ET-1 is generated from big ET-1 by endothelin-converting enzyme (ECE)-1, which has four recognized isofor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::342399ec0b93a24d0ccaa22b36849537
https://pubmed.ncbi.nlm.nih.gov/16741058
https://pubmed.ncbi.nlm.nih.gov/16741058
Publikováno v:
International journal of cancer. 118(7)
The present study focused on the endothelin axis in human oral squamous cell carcinoma (SCC) cells. We investigated the expression and distribution of endothelin-1 (ET-1), its receptors (endothelin-A receptor (ETAR) and endothelin-B receptor (ETBR))
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec7da6dbd9c83ac9e77c7c10e5493446
https://pubmed.ncbi.nlm.nih.gov/16217751
https://pubmed.ncbi.nlm.nih.gov/16217751
Publikováno v:
British Journal of Cancer
Perturbations of stromal-epithelial interactions in the developing tumour can contribute to cancer invasion and metastasis. The structurally related metallopeptidases endothelin-converting enzyme (ECE) and neutral endopeptidase (NEP) contribute seque
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7779470c911f45a0483a0f76fc3106e4
https://pubmed.ncbi.nlm.nih.gov/15083188
https://pubmed.ncbi.nlm.nih.gov/15083188
Publikováno v:
Clinical science (London, England : 1979). 103
Neutral endopeptidase-24.11 (neprilysin; NEP/CD10) is a cell surface metallopeptidase expressed by prostatic epithelial cells that degrades various bioactive peptides including endothelin. Endothelin-converting enzyme (ECE), the key enzyme of endothe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::333955d08af26ecc906506b5b43c11dd
https://pubmed.ncbi.nlm.nih.gov/12193112
https://pubmed.ncbi.nlm.nih.gov/12193112
Autor:
Daniel Navarro, Badar A. Usmani, Makoto Sumitomo, Louis B. Hersh, Dianne O. Hardy, David M. Nanus, Jie Dai, Margaret A. Shipp, Leonard P. Freedman, Christos N. Papandreou, Ruoqian Shen
Publikováno v:
Molecular and cellular endocrinology. 170(1-2)
Transcription of the human neutral endopeptidase 24.11 (NEP) gene is androgen regulated in prostate cancer cells. Homology search identified a sequence GTCACAaagAGTTCT similar to the ARE consensus sequence GGTACAnnnTGTTCT within the 3′-untranslated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f75b9e7ce919888a852e4da7e2b4348a
https://pubmed.ncbi.nlm.nih.gov/11162897
https://pubmed.ncbi.nlm.nih.gov/11162897
Publikováno v:
European Urology Supplements. 5:798
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1aed10c09bd28db3f91bafb92ba30354
https://doi.org/10.1016/s1569-9056(06)61296-7
https://doi.org/10.1016/s1569-9056(06)61296-7