Evolution and Population Dynamics of Clonal Complex 152 Community-Associated Methicillin-Resistant Staphylococcus aureus

Autor: Aina Elisabeth Fossum Moen, Marc Stegger, Paal Skytt Andersen, Ivana Cirkovic, Frieder Schaumburg, Frédéric Laurent, Berit Lilje, Graeme R. Nimmo, Patricia Martins Simoes, Anne Tristan, Sara Mernelius, Sharmin Baig, Thor Bech Johannesen, Michael Z. David, Dominique S. Blanc, Anders Rhod Larsen, Iris Spiliopoulou, Beverly Egyir

Publikováno v: Baig, S, Rhod Larsen, A, Martins Simões, P, Laurent, F, Johannesen, T B, Lilje, B, Tristan, A, Schaumburg, F, Egyir, B, Cirkovic, I, Nimmo, G R, Spiliopoulou, I, Blanc, D S, Mernelius, S, Moen, A E F, David, M Z, Andersen, P S & Stegger, M 2020, ' Evolution and Population Dynamics of Clonal Complex 152 Community-Associated Methicillin-Resistant Staphylococcus aureus ', mSphere, vol. 5, no. 4, e00226-20 . https://doi.org/10.1128/mSphere.00226-20
mSphere, vol. 5, no. 4, pp. e00226-20
mSphere, Vol 5, Iss 4, p e00226-20 (2020)
mSphere, Vol 5, Iss 4 (2020)

Since the late 1990s, changes in the epidemiology of methicillin-resistant Staphylococcus aureus (MRSA) were recognized with the emergence of community-associated MRSA (CA-MRSA). CA-MRSA belonging to clonal complex 152 (CC152), carrying the small sta

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::faa237d664bcceeaa4f48aff32e2d8f7
https://doi.org/10.1128/msphere.00226-20

The pore structure of Clostridium perfringens epsilon toxin

Autor: Savva, Christos, Clark, Alice, Naylor, Claire, Popoff, Michel, Moss, David, Basak, Ajit, Titball, Richard, Bokori-Brown, Monika

Publikováno v: Nature Communications
Nature Communications, Nature Publishing Group, 2019, 10 (1), pp.2641. ⟨10.1038/s41467-019-10645-8⟩
Nature Communications, 2019, 10 (1), pp.2641. ⟨10.1038/s41467-019-10645-8⟩

Epsilon toxin (Etx), a potent pore forming toxin (PFT) produced by Clostridium perfringens, is responsible for the pathogenesis of enterotoxaemia of ruminants and has been suggested to play a role in multiple sclerosis in humans. Etx is a member of t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::03b5647c6160a8077e0ad0ee01cd113c
https://hal-pasteur.archives-ouvertes.fr/pasteur-02454060

A dual role in regulation and toxicity for the disordered N-terminus of the toxin GraT

Autor: Rita Hõrak, Andres Ainelo, Ariel Talavera, Frank Sobott, Hedvig Tamman, Abel Garcia-Pino, San Hadži, Albert Konijnenberg, Remy Loris

Publikováno v: Nature communications, 10 (1
Nature communications
Nature Communications
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)

Bacterial toxin-antitoxin (TA) modules are tightly regulated to maintain growth in favorable conditions or growth arrest during stress. A typical regulatory strategy involves the antitoxin binding and repressing its own promoter while the toxin often

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b31066fee2711a82f38e73e3132c5013
http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/285238

Genomics of the new species Kingella negevensis: diagnostic issues and identification of a locus encoding a RTX toxin

Autor: Trestan Pillonel, Gilbert Greub, Guy Prod'hom, Sacha Laurent, Marie Léger, Onya Opota, Katia Jaton, Sabrina Trachsel

Publikováno v: Microbes and infection, vol. 19, no. 11, pp. 546-552

Kingella kingae, producing the cytotoxic RTX protein, is a causative agent of serious infections in humans such as bacteremia, endocarditis and osteoarticular infection, especially in young children. Recently, Kingella negevensis, a related species,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eaca04d60232415441281100cf821587
https://serval.unil.ch/notice/serval:BIB_A2A9CDA1BE86

Immunoadjuvant Properties of the Rho Activating Factor CNF1 in Prophylactic and Curative Vaccination against Leishmania infantum

Autor: Laurent Boyer, Emmanuel Lemichez, Nassim Mathal, Bernard Ferrua, Daniel Gillet, Patrick Munro, Pierre Marty, Grégory Michel

Publikováno v: PLoS ONE
PLoS ONE, Public Library of Science, 2016, 11 (6), pp.e0156363. ⟨10.1371/journal.pone.0156363⟩
PLoS ONE, 2016, 11 (6), pp.e0156363. ⟨10.1371/journal.pone.0156363⟩
PLoS ONE, Vol 11, Iss 6, p e0156363 (2016)

International audience; There is a need to develop new effective immunoadjuvants for prophylactic or therapeutic vaccines against intracellular pathogens. The activation of Rho GTPases by bacterial cytotoxic necrotizing factor 1 (CNF1) elicits humora

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a1f77f9778853c4e7867852f5a580f2
https://hal-pasteur.archives-ouvertes.fr/pasteur-02448913/document