Functional Studies on Membrane Proteins by Means of H/D Exchange in Infrared: Structural Changes in Na(+) NQR from V. cholerae in the Presence of Lipids

Autor: Petra Hellwig, Sebastien Kriegel, Blanca Barquera, Yashvin Neehaul

Publikováno v: Membrane Protein Structure and Function Characterization. Methods in Molecular Biology
Membrane Protein Structure and Function Characterization. Methods in Molecular Biology, 1635, Humana Press, 2017, 978-1-4939-7151-0. ⟨10.1007/978-1-4939-7151-0_13⟩
Methods in Molecular Biology ISBN: 9781493971497

H/D exchange kinetics at the level of the amide proton in the mid infrared (1700-1500 cm(-1)) make it possible to study the conformational flexibility of membrane proteins, independent of size or the presence of detergent or lipids. Slow, medium, and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e66f1936d5c8072b52e64c13c4d8bef5
https://hal.archives-ouvertes.fr/hal-03338655

Two independent routes of de novo vitamin B6 biosynthesis: not that different after all

Autor: Barbara Kappes, Peter Macheroux, Ivo Tews, Thomas Raschle, Nikolaus Amrhein, Thérésa Bridget Fitzpatrick

Publikováno v: Biochemical Journal, Vol. 407, No 1 (2007) pp. 1-13

Vitamin B6 is well known in its biochemically active form as pyridoxal 5′-phosphate, an essential cofactor of numerous metabolic enzymes. The vitamin is also implicated in numerous human body functions ranging from modulation of hormone function to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68dbd4bfb53601ea357978da880b9cb2
https://doi.org/10.1042/bj20070765

Intersubunit cross-talk in pyridoxal 5'-phosphate synthase, coordinated by the C terminus of the synthase subunit

Autor: Peter Gehrig, Thomas Raschle, Nikolaus Amrhein, Thérésa Bridget Fitzpatrick, Davide Speziga, Eilika Weber-Ban, Cyril Moccand, Wolfgang Kress

Publikováno v: Journal of Biological Chemistry, Vol. 284, No 12 (2009) pp. 7706-7718

Vitamin B6 is essential in all organisms, due to its requirement as a cofactor in the form of pyridoxal 5′-phosphate (PLP) for key metabolic enzymes. It can be synthesized de novo by either of two pathways known as deoxyxylulose 5-phosphate (DXP)-d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe40dc85f12dcce026d9c354466412bb

Structure and function of YcnD from Bacillus subtilis, a flavin-containing oxidoreductase

Autor: Karl Gruber, Thérésa Bridget Fitzpatrick, Christoph Kratky, Alexander Morokutti, Peter Macheroux, Andrzej Franciszek Lyskowski, Sonja Sollner, Eva Maria Pointner

Publikováno v: Biochemistry, Vol. 44, No 42 (2005) pp. 13724-33

YcnD from the gram-positive bacterium Bacillus subtilis is a member of a family of bacterial proteins that act as NADH- and/or NADPH-dependent oxidoreductases. Here, we report for the first time on the biochemical characterization of the purified pro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91c6f5ad04ea7c97deb4aba059e5d6d2
https://archive-ouverte.unige.ch/unige:89529

A possible mechanism for metal-ion induced DNA-protein dissociation in a family of prokaryotic transcriptional regulators

Autor: Amos Bairoch

Publikováno v: Nucleic Acids Research, Vol. 21, No 10 (1993) P. 2515
Scopus-Elsevier

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae5a743e51c38c7817ec62d197ff9894
https://archive-ouverte.unige.ch/unige:36851