TGF-beta receptor 2 downregulation in tumour-associated stroma worsens prognosis and high-grade tumours show more tumour-associated macrophages and lower TGF-beta1 expression in colon carcinoma: a retrospective study

Autor: Papadopoulos Thomas, Croner Roland, Merkel Susanne, Bacman David, Brueckl Wolfgang, Dimmler Arno

Publikováno v: BMC Cancer, Vol 7, Iss 1, p 156 (2007)

Abstract Background Histological phenotype and clinical behaviour of malignant tumours are not only dependent on alterations in the epithelial cell compartment, but are affected by their interaction with inflammatory cells and tumour-associated strom

Externí odkaz: https://doaj.org/article/118423e90afc4abb8d20369d4324d5fa

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.

Detection of interstellar oxidaniumyl: abundant H2O+ towards the star-forming regions DR21, Sgr B2, and NGC6334

Autor: Ossenkopf, V., Müller, H. S. P., Lis, D. C., Schilke, P., Bell, T. A., Bruderer, S., Bergin, E., Ceccarelli, C., Comito, C., Stutzki, J., Bacman, A., Baudry, A., Benz, A. O., Benedettini, M., Berne, O., Blake, G., Boogert, A., Bottinelli, S., Boulanger, F., Cabrit, S., Caselli, P., Caux, E., Cernicharo, J., Codella, C., Coutens, A., Crimier, N., Crockett, N. R., Daniel, F., Demyk, K., Dieleman, P., Dominik, C., Dubernet, M. L., Emprechtinger, M., Encrenaz, P., Falgarone, E., France, K., Fuente, A., Gerin, M., Giesen, T. F., di Giorgio, A. M., Goicoechea, J. R., Goldsmith, P. F., Güsten, R., Harris, A., Helmich, F., Herbst, E., Hily-Blant, P., Jacobs, K., Jacq, T., Joblin, Ch., Johnstone, D., Kahane, C., Kama, M., Klein, T., Klotz, A., Kramer, C., Langer, W., Lefloch, B., Leinz, C., Lorenzani, A., Lord, S. D., Maret, S., Martin, P. G., Martin-Pintado, J., McCoey, C., Melchior, M., Melnick, G. J., Menten, K. M., Mookerjea, B., Morris, P., Murphy, J. A., Neufeld, D. A., Nisini, B., Pacheco, S., Pagani, L., Parise, B., Pearson, J. C., Pérault, M., Phillips, T. G., Plume, R., Quin, S. -L., Rizzo, R., Röllig, M., Salez, M., Saraceno, P., Schlemmer, S., Simon, R., Schuster, K., van der Tak, F. F. S., Tielens, A. G. G. M., Teyssier, D., Trappe, N., Vastel, C., Viti, S., Wakelam, V., Walters, A., Wang, S., Whyborn, N., van der Wiel, M., Yorke, H. W., Yu, S., Zmuidzinas, J.

Publikováno v: Astron. Astrophys. 518 (2010) Art. No. L111

We identify a prominent absorption feature at 1115 GHz, detected in first HIFI spectra towards high-mass star-forming regions, and interpret its astrophysical origin. The characteristic hyperfine pattern of the H2O+ ground-state rotational transition

Externí odkaz: http://arxiv.org/abs/1005.2521

Selective Elimination of Mitochondrial Mutations in the Germline by Genome Editing

Autor: Reddy, Pradeep, Ocampo, Alejandro, Suzuki, Keiichiro, Luo, Jinping, Bacman, Sandra R., Williams, Sion L., Sugawara, Atsushi, Okamura, Daiji, Tsunekawa, Yuji, Wu, Jun, Lam, David, Xiong, Xiong, Montserrat, Nuria, Esteban, Concepcion Rodriguez, Liu, Guang-Hui, Sancho-Martinez, Ignacio, Manau, Dolors, Civico, Salva, Cardellach, Francesc, del Mar O’Callaghan, Maria, Campistol, Jaime, Zhao, Huimin, Campistol, Josep M., Moraes, Carlos T., Izpisua Belmonte, Juan Carlos

Publikováno v: In Cell 23 April 2015 161(3):459-469