Zobrazeno 1 - 10
of 1 982
pro vyhledávání: '"Bacman"'
Autor:
Andressa Peres de Oliveira, Claudia D. C. Navarro, Pedro Rafael F. Dias, Tania Arguello, Brittni R. Walker, Sandra R. Bacman, Lizandra Maia Sousa, Roger F. Castilho, Sílvio R. Consonni, Carlos T. Moraes, Jörg Kobarg
Publikováno v:
Proteome Science, Vol 22, Iss 1, Pp 1-18 (2024)
Abstract Background NEK10, a serine/threonine/tyrosine kinase belonging to the NEK (NIMA-related kinases) family, has been associated with diverse cellular processes. However, no specific target pathways have been identified. Our previous work knocki
Externí odkaz:
https://doaj.org/article/61aca976131e497f9613dfcf146b8532
Autor:
Brittni R Walker, Lise-Michelle Theard, Milena Pinto, Monica Rodriguez-Silva, Sandra R Bacman, Carlos T Moraes
Publikováno v:
EMBO Molecular Medicine, Vol 16, Iss 9, Pp 2210-2232 (2024)
Abstract Oxidative Phosphorylation (OXPHOS) defects can cause severe encephalopathies and no effective treatment exists for these disorders. To assess the ability of gene replacement to prevent disease progression, we subjected two different CNS-defi
Externí odkaz:
https://doaj.org/article/7ee838787fdb4b8a8f0b8075974cedd6
Autor:
Nneka Southwell, Onorina Manzo, Sandra Bacman, Dazhi Zhao, Nicole M Sayles, Jalia Dash, Keigo Fujita, Marilena D’Aurelio, Annarita Di Lorenzo, Giovanni Manfredi, Hibiki Kawamata
Publikováno v:
EMBO Molecular Medicine, Vol 16, Iss 6, Pp 1352-1378 (2024)
Abstract Mutations in CHCHD10, a mitochondrial protein with undefined functions, are associated with autosomal dominant mitochondrial diseases. Chchd10 knock-in mice harboring a heterozygous S55L mutation (equivalent to human pathogenic S59L) develop
Externí odkaz:
https://doaj.org/article/06da78e884b74bbabfb6411ca3018288
Conference
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Autor:
Bacman, Sandra R., Barrera-Paez, Jose Domingo, Pinto, Milena, Van Booven, Derek, Stewart, James B., Griswold, Anthony J., Moraes, Carlos T.
Publikováno v:
In Molecular Therapy - Nucleic Acids 12 March 2024 35(1)
Autor:
Sandra R. Bacman, Jose Domingo Barrera-Paez, Milena Pinto, Derek Van Booven, James B. Stewart, Anthony J. Griswold, Carlos T. Moraes
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 35, Iss 1, Pp 102132- (2024)
Mutations within mtDNA frequently give rise to severe encephalopathies. Given that a majority of these mtDNA defects exist in a heteroplasmic state, we harnessed the precision of mitochondrial-targeted TALEN (mitoTALEN) to selectively eliminate mutan
Externí odkaz:
https://doaj.org/article/18fda293f23a4e2c95e8138f074d89c9
Autor:
Walker BR; Neuroscience Graduate Program, University of Miami Miller School of Medicine, Miami, USA., Theard LM; Department of Neurology, University of Miami Miller School of Medicine, Miami, USA., Pinto M; Department of Neurology, University of Miami Miller School of Medicine, Miami, USA.; Mitobridge Inc, Cambridge, MA, USA., Rodriguez-Silva M; Department of Neurology, University of Miami Miller School of Medicine, Miami, USA., Bacman SR; Department of Neurology, University of Miami Miller School of Medicine, Miami, USA., Moraes CT; Department of Neurology, University of Miami Miller School of Medicine, Miami, USA. cmoraes@med.miami.edu.; Department of Ophthalmology, University of Miami Miller School of Medicine, Miami, USA. cmoraes@med.miami.edu.; Department of Cell Biology, University of Miami Miller School of Medicine, Miami, USA. cmoraes@med.miami.edu.
Publikováno v:
EMBO molecular medicine [EMBO Mol Med] 2024 Sep; Vol. 16 (9), pp. 2210-2232. Date of Electronic Publication: 2024 Aug 21.
Akademický článek
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Publikováno v:
In Journal of Biological Chemistry November 2022 298(11)
Autor:
Southwell N; Feil Family Brain and Mind Research Institute, Weill Cornell Medicine, 407 East 61st Street, New York, NY, 10065, USA.; Neuroscience Graduate Program, Weill Cornell Graduate School of Medical Sciences, 1300 York Ave, New York, NY, 10065, USA., Manzo O; Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, 1300 York Avenue, New York, NY, 10065, USA., Bacman S; Department of Neurology, University of Miami, 1600 NW 10th Ave, Miami, FL, 33161, USA., Zhao D; Feil Family Brain and Mind Research Institute, Weill Cornell Medicine, 407 East 61st Street, New York, NY, 10065, USA., Sayles NM; Feil Family Brain and Mind Research Institute, Weill Cornell Medicine, 407 East 61st Street, New York, NY, 10065, USA.; Neuroscience Graduate Program, Weill Cornell Graduate School of Medical Sciences, 1300 York Ave, New York, NY, 10065, USA., Dash J; Feil Family Brain and Mind Research Institute, Weill Cornell Medicine, 407 East 61st Street, New York, NY, 10065, USA., Fujita K; Millburn High School, 462 Millburn Ave, Millburn, NJ, 07041, USA., D'Aurelio M; Feil Family Brain and Mind Research Institute, Weill Cornell Medicine, 407 East 61st Street, New York, NY, 10065, USA., Di Lorenzo A; Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, 1300 York Avenue, New York, NY, 10065, USA., Manfredi G; Feil Family Brain and Mind Research Institute, Weill Cornell Medicine, 407 East 61st Street, New York, NY, 10065, USA., Kawamata H; Feil Family Brain and Mind Research Institute, Weill Cornell Medicine, 407 East 61st Street, New York, NY, 10065, USA. hik2004@med.cornell.edu.
Publikováno v:
EMBO molecular medicine [EMBO Mol Med] 2024 Jun; Vol. 16 (6), pp. 1352-1378. Date of Electronic Publication: 2024 May 09.