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Neurodevelopmental outcome at 2 years of age after general anaesthesia and awake-regional anaesthesia in infancy (GAS): an international multicentre, randomised controlled trial

Autor: Davidson, Aj, Frawley, G, Hardy, P, Arnup, Sj, Schuster, T, Lee, K, Hunt, Rw, Stargatt, R, Sheppard, S, Ormond, Gd, Hartmann, Pl, Takagi, Mj, Malarbi, S, Doyle, M, Ragg, P, Backstrom, M, Costi, D, von Ungern Sternberg, Bs, Wilton, Nc, Knottenbelt, G, Disma, NICOLA MASSIMO, Montobbio, G, Mameli, L, Tuo, P, Girbaldi, G, PINI PRATO, Alessio, Mattioli, Girolamo, Wolfler, A, Izzo, F, Salvo, I, Sonzogni, V, Locatelli, Bg, Khotcholava, M, de Graaff, Jc, van Gool, Jt, Numan, Sc, van Veldhuijzen, D, Kalkman, Cj, van Baar, Al, Steenis, Lj, Hagenaars, Jh, Absalom, Ar, Hoekstra, Fm, Volkers, M, Withington, D, Furue, K, Gaudreault, J, Mccann, Me, Berde, C, Soriano, S, Young, V, Sethna, N, Kovatsis, P, Cravero, J, Bellinger, D, Marmor, J, Lynn, A, Ivanova, I, Hunyady, A, Verma, S, Polaner, D, Thomas, J, Mueller, M, Haret, D, Szmuk, P, Steiner, J, Kravitz, B, Surantham, S, Hays, S, Taenzer, A, Maxwell, L, Williams, Rk, Morton, Ns, Bell, G, Dorris, L, Adey, C, Pownall, J, Bagshaw, O, Chisakuta, A, Eissa, A, Stoddart, P, Davis, A, Myles, P, Withngton, De, Degraaff, Jc, Bellinger, Dc, Wolf, A, Mcintosh, N, Carlin, J, Leslie, K, de Lima, J, Hammer, G, Field, D, Gebski, V, Tibboel, D.

Publikováno v: The Lancet, 387(10015), 239. Lancet Publishing Group
The Lancet, 387(10015), 239-250. ELSEVIER SCIENCE INC
The Lancet, 387(10015), 239. Elsevier Limited

Background Preclinical data suggest that general anaesthetics affect brain development. There is mixed evidence from cohort studies that young children exposed to anaesthesia can have an increased risk of poor neurodevelopmental outcome. We aimed to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35e8a18f3d6b0e8518d7e05027ec1409
https://doi.org/10.1016/s0140-6736(15)00608-x

Implication of Major Adverse Postoperative Events and Myocardial Injury on Disability and Survival: A Planned Subanalysis of the ENIGMA-II Trial

Autor: C. Osborne, Gudrun Kunst, Packianathaswamy Balaji, Ming Le, McMillan H, R Cotter, Koo Egy, Alzahrani T, Matthew T. Hutcherson, R. Sneyd, Chua N, Egan C, Jeremy M D Nightingale, Hesler B, N. Buckley, Fong Acm, Brendan S. Silbert, A. Ditoro, Jo Carroll, W.S. Beattie, Backstrom M, Michael J. Paech, S. March, N. Badner, D. I. Sessler, M. Dickinson, Michael J. Jacka, Bryant D, Bryden C, D. Mcallister, McRae R, Thomas Schricker, W. Galagher, Balachundhar Subramaniam, Fiffick An, Eldawlatly A, R Ross Kennedy, E O'Loughlin, Iannuzzi D, Crump D, Mitteregger, Stuart Walker, Detlef Obal, S. Baulch, Parkinson I, Tidy T, Fahlbusch D, Sidiropoulos S, S. Said, Catherine Farrington, Andrea Kurz, Naylor A, Banner-Godspeed, Bulach R, Andrew Brennan, Duminda N. Wijeysundera, Cheng Bcp, Jefferies A, Paul S. Myles, Philip J Peyton, Mohd N, Lattermann R, Kate Leslie, Thompson G, Chan Mtv, Reeves M, Richard Halliwell, D. Campbell, Liu J, Tsang Mwy, Jennifer Cope, Alparslan Turan, Chu Lcy, Fu Ay, Stephen Bolsin, Cooke E, S. Olliff, Sophie Wallace

Publikováno v: Anesthesia and analgesia. 127(5)

BACKGROUND: Globally, >300 million patients have surgery annually, and ≤20% experience adverse postoperative events. We studied the impact of both cardiac and noncardiac adverse events on 1-year disability-free survival after noncardiac surgery. ME

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2cd5c13036e1a1473db7b6ddc8639b8
https://pubmed.ncbi.nlm.nih.gov/29533264

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