APPsα Rescues Tau-Induced Synaptic Pathology.

Autor: Bold CS; Institute of Pharmacy and Molecular Biotechnology, Ruprecht Karls Universität Heidelberg, Heidelberg, 69120, Germany., Baltissen D; Institute of Pharmacy and Molecular Biotechnology, Ruprecht Karls Universität Heidelberg, Heidelberg, 69120, Germany., Ludewig S; TU Braunschweig, Zoological Institute, Braunschweig, 38106, Germany.; Helmholtz Centre for Infection Research, Neuroinflammation and Neurodegeneration Group, Braunschweig, 38124, Germany., Back MK; Institute of Pathophysiology, University Medical Center of the Johannes Gutenberg University Mainz, Mainz, 55128, Germany., Just J; TU Braunschweig, Zoological Institute, Braunschweig, 38106, Germany., Kilian L; Institute of Pharmacy and Molecular Biotechnology, Ruprecht Karls Universität Heidelberg, Heidelberg, 69120, Germany., Erdinger S; Institute of Pharmacy and Molecular Biotechnology, Ruprecht Karls Universität Heidelberg, Heidelberg, 69120, Germany., Banicevic M; Institute of Pharmacy and Molecular Biotechnology, Ruprecht Karls Universität Heidelberg, Heidelberg, 69120, Germany., Rehra L; Institute of Pharmacy and Molecular Biotechnology, Ruprecht Karls Universität Heidelberg, Heidelberg, 69120, Germany., Almouhanna F; Institute of Physiology and Pathophysiology, Ruprecht Karls Universität Heidelberg, Heidelberg, 69120, Germany., Nigri M; Institute of Anatomy, University of Zurich, Zurich, 8057, Switzerland., Wolfer DP; Institute of Anatomy, University of Zurich, Zurich, 8057, Switzerland.; Institute of Human Movement Sciences and Sport, ETH Zurich, Zurich, Switzerland., Spilger R; BioQuant Center, Institute of Pharmacy and Molecular Biotechnology, Ruprecht Karls Universität Heidelberg and DKFZ, Heidelberg, 69120, Germany., Rohr K; BioQuant Center, Institute of Pharmacy and Molecular Biotechnology, Ruprecht Karls Universität Heidelberg and DKFZ, Heidelberg, 69120, Germany., Kann O; Institute of Physiology and Pathophysiology, Ruprecht Karls Universität Heidelberg, Heidelberg, 69120, Germany., Buchholz CJ; Paul-Ehrlich-Institut, Langen, 63225, Germany., von Engelhardt J; Institute of Pathophysiology, University Medical Center of the Johannes Gutenberg University Mainz, Mainz, 55128, Germany., Korte M; TU Braunschweig, Zoological Institute, Braunschweig, 38106, Germany.; Helmholtz Centre for Infection Research, Neuroinflammation and Neurodegeneration Group, Braunschweig, 38124, Germany., Müller UC; Institute of Pharmacy and Molecular Biotechnology, Ruprecht Karls Universität Heidelberg, Heidelberg, 69120, Germany u.mueller@urz.uni-heidelberg.de.

Publikováno v: The Journal of neuroscience : the official journal of the Society for Neuroscience [J Neurosci] 2022 Jul 20; Vol. 42 (29), pp. 5782-5802. Date of Electronic Publication: 2022 Jun 06.

The angiopoietin-Tie2 pathway regulates Purkinje cell dendritic morphogenesis in a cell-autonomous manner.

Autor: Luck R; European Center of Angioscience (ECAS), Medical Faculty Mannheim, University of Heidelberg, 68167 Mannheim, Germany., Karakatsani A; European Center of Angioscience (ECAS), Medical Faculty Mannheim, University of Heidelberg, 68167 Mannheim, Germany., Shah B; European Center of Angioscience (ECAS), Medical Faculty Mannheim, University of Heidelberg, 68167 Mannheim, Germany., Schermann G; European Center of Angioscience (ECAS), Medical Faculty Mannheim, University of Heidelberg, 68167 Mannheim, Germany., Adler H; European Center of Angioscience (ECAS), Medical Faculty Mannheim, University of Heidelberg, 68167 Mannheim, Germany., Kupke J; Department of Neurobiology, Interdisciplinary Centre for Neurosciences (IZN), University of Heidelberg, 69120 Heidelberg, Germany., Tisch N; European Center of Angioscience (ECAS), Medical Faculty Mannheim, University of Heidelberg, 68167 Mannheim, Germany., Jeong HW; Department of Tissue Morphogenesis, Max Planck Institute for Molecular Biomedicine, and University of Münster, Faculty of Medicine, 48149 Münster, Germany., Back MK; Institute of Pathophysiology, Focus Program Translational Neuroscience (FTN), University Medical Center of the Johannes Gutenberg University Mainz, 55131 Mainz, Germany., Hetsch F; Institute of Pathophysiology, Focus Program Translational Neuroscience (FTN), University Medical Center of the Johannes Gutenberg University Mainz, 55131 Mainz, Germany., D'Errico A; Institute of Cell Biology and Neuroscience and Buchmann Institute for Molecular Life Sciences (BMLS), University of Frankfurt, 60323 Frankfurt, Germany., De Palma M; Swiss Institute for Experimental Cancer Research (ISREC), Swiss Federal Institute of Technology in Lausanne (EPFL), 1015 Lausanne, Switzerland., Wiedtke E; Department of Infectious Diseases/Virology, Medical Faculty, University of Heidelberg, Bioquant Center, 69120 Heidelberg, Germany., Grimm D; Department of Infectious Diseases/Virology, Medical Faculty, University of Heidelberg, Bioquant Center, 69120 Heidelberg, Germany; German Center for Infection Research (DZIF), and German Center for Cardiovascular Research (DZHK), Heidelberg, Germany., Acker-Palmer A; Institute of Cell Biology and Neuroscience and Buchmann Institute for Molecular Life Sciences (BMLS), University of Frankfurt, 60323 Frankfurt, Germany., von Engelhardt J; Institute of Pathophysiology, Focus Program Translational Neuroscience (FTN), University Medical Center of the Johannes Gutenberg University Mainz, 55131 Mainz, Germany., Adams RH; Department of Tissue Morphogenesis, Max Planck Institute for Molecular Biomedicine, and University of Münster, Faculty of Medicine, 48149 Münster, Germany., Augustin HG; European Center of Angioscience (ECAS), Medical Faculty Mannheim, University of Heidelberg, 68167 Mannheim, Germany; Division of Vascular Oncology and Metastasis, German Cancer Research Center Heidelberg (DKFZ-ZMBH Alliance), 69120 Heidelberg, Germany., Ruiz de Almodóvar C; European Center of Angioscience (ECAS), Medical Faculty Mannheim, University of Heidelberg, 68167 Mannheim, Germany. Electronic address: carmen.ruizdealmodovar@medma.uni-heidelberg.de.

Publikováno v: Cell reports [Cell Rep] 2021 Aug 17; Vol. 36 (7), pp. 109522.

Amyloid Beta-Mediated Changes in Synaptic Function and Spine Number of Neocortical Neurons Depend on NMDA Receptors.

Autor: Back MK; Institute of Pathophysiology, Focus Program Translational Neuroscience (FTN), University Medical Center of the Johannes Gutenberg, University Mainz, 55128 Mainz, Germany., Ruggieri S; Institute of Pathophysiology, Focus Program Translational Neuroscience (FTN), University Medical Center of the Johannes Gutenberg, University Mainz, 55128 Mainz, Germany., Jacobi E; Institute of Pathophysiology, Focus Program Translational Neuroscience (FTN), University Medical Center of the Johannes Gutenberg, University Mainz, 55128 Mainz, Germany., von Engelhardt J; Institute of Pathophysiology, Focus Program Translational Neuroscience (FTN), University Medical Center of the Johannes Gutenberg, University Mainz, 55128 Mainz, Germany.

Publikováno v: International journal of molecular sciences [Int J Mol Sci] 2021 Jun 11; Vol. 22 (12). Date of Electronic Publication: 2021 Jun 11.

Effect of Atorvastatin on Growth Differentiation Factor-15 in Patients with Type 2 Diabetes Mellitus and Dyslipidemia.

Autor: Kim JM; Research Center for Endocrine and Metabolic Diseases, Chungnam National University Hospital, Chungnam National University School of Medicine, Daejeon, Korea.; Department of Internal Medicine, Chungnam National University Hospital, Chungnam National University School of Medicine, Daejeon, Korea., Back MK; Department of Internal Medicine, Chungnam National University Hospital, Chungnam National University School of Medicine, Daejeon, Korea., Yi HS; Research Center for Endocrine and Metabolic Diseases, Chungnam National University Hospital, Chungnam National University School of Medicine, Daejeon, Korea.; Department of Internal Medicine, Chungnam National University Hospital, Chungnam National University School of Medicine, Daejeon, Korea., Joung KH; Research Center for Endocrine and Metabolic Diseases, Chungnam National University Hospital, Chungnam National University School of Medicine, Daejeon, Korea.; Department of Internal Medicine, Chungnam National University Hospital, Chungnam National University School of Medicine, Daejeon, Korea., Kim HJ; Research Center for Endocrine and Metabolic Diseases, Chungnam National University Hospital, Chungnam National University School of Medicine, Daejeon, Korea.; Department of Internal Medicine, Chungnam National University Hospital, Chungnam National University School of Medicine, Daejeon, Korea. kimhj43@cnuh.co.kr., Ku BJ; Research Center for Endocrine and Metabolic Diseases, Chungnam National University Hospital, Chungnam National University School of Medicine, Daejeon, Korea.; Department of Internal Medicine, Chungnam National University Hospital, Chungnam National University School of Medicine, Daejeon, Korea. bonjeong@cnu.ac.kr.

Publikováno v: Diabetes & metabolism journal [Diabetes Metab J] 2016 Feb; Vol. 40 (1), pp. 70-8.

(E)-2,4-Bis(p-hydroxyphenyl)-2-butenal enhanced TRAIL-induced apoptosis in ovarian cancer cells through downregulation of NF-κB/STAT3 pathway.

Autor: Cho SH; College of Pharmacy, Medical Research Center, Chungbuk National University, 12, Gaeshin-dong, Heungduk-gu, Ch'ongju, 361-763, Chungbuk, Korea., Park MH, Lee HP, Back MK, Sung HC, Chang HW, Kim JH, Jeong HS, Han SB, Hong JT

Publikováno v: Archives of pharmacal research [Arch Pharm Res] 2014 May; Vol. 37 (5), pp. 652-61. Date of Electronic Publication: 2014 Jan 04.