Zobrazeno 1 - 10
of 293
pro vyhledávání: '"Bac transgenic"'
Akademický článek
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Autor:
Yukiko Ito, Naoko Inoue, Yukiko U. Inoue, Shoko Nakamura, Yoshiki Matsuda, Masumi Inagaki, Takahiro Ohkubo, Junko Asami, Youhei W. Terakawa, Shinichi Kohsaka, Yu-ichi Goto, Chihiro Akazawa, Takayoshi Inoue, Ken Inoue
Publikováno v:
Neurobiology of Disease, Vol 80, Iss , Pp 1-14 (2015)
Distinct classes of SOX10 mutations result in peripheral demyelinating neuropathy, central dysmyelinating leukodystrophy, Waardenburg syndrome, and Hirschsprung disease, collectively known as PCWH. Meanwhile, SOX10 haploinsufficiency caused by alleli
Externí odkaz:
https://doaj.org/article/3d3bfe4859514db89eb3827407b0bb9a
Autor:
Keke Ren, Baolin Guo, Chunqiu Dai, Han Yao, Tangna Sun, Xia Liu, Zhantao Bai, Wenting Wang, Shengxi Wu
Publikováno v:
Frontiers in Neural Circuits, Vol 11 (2017)
As the main input nucleus of the basal ganglion, the striatum executes different functions, including motivation, reward and attention. The functions of the striatum highly rely on its subregions that receive projections from various cortical areas a
Externí odkaz:
https://doaj.org/article/2f966857d9c74386a92d5488da61d34d
Autor:
Sherri L. Thiele, Betty Chen, Charlotte Lo, Tracey S. Gertler, Ruth Warre, James D. Surmeier, Jonathan M. Brotchie, Joanne E. Nash
Publikováno v:
Neurobiology of Disease, Vol 71, Iss , Pp 334-344 (2014)
Parkinsonian symptoms arise due to over-activity of the indirect striatal output pathway, and under-activity of the direct striatal output pathway. l-DOPA-induced dyskinesia (LID) is caused when the opposite circuitry problems are established, with t
Externí odkaz:
https://doaj.org/article/0e3d4e4c5e6e4ecd84c9c2d0a22e3be0
Autor:
Mizuho Yamato, Mohamed Abdelhakim, Atsushi Sakai, Masatsugu Ema, Teruyuki Dohi, Rei Ogawa, Hiroya Takada, Shigetomo Fukuhara, Hidenori Suzuki
Publikováno v:
Plastic & Reconstructive Surgery. 148:89-99
BACKGROUND Neovascularization plays a critical role in skin graft survival. Up to date, the lack of specificity to solely track the newly sprouting blood vessels has remained a limiting factor in skin graft transplantation models. Therefore, the auth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19b2b712c5d96b6238a0f165c513e19e
https://doi.org/10.1097/prs.0000000000008039
https://doi.org/10.1097/prs.0000000000008039
Autor:
Christian Lohr, Daniela Hirnet, Tanja Nußbaum, Peter Illes, Ralf Hausmann, Stefan M Singheiser, Janka Günther, Michaela Schumacher, Ronald Jabs, Marcus Grohmann, Heike Franke, Günther Schmalzing, Zoltan Gerevich, Florian Wildner
Publikováno v:
Purinergic Signalling
Extracellular purines are important signaling molecules involved in numerous physiological and pathological processes via the activation of P2 receptors. Information about the spatial and temporal P2 receptor (P2R) expression and its regulation remai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::743932240eaace9aa020733966d57285
http://europepmc.org/articles/PMC8410928
http://europepmc.org/articles/PMC8410928
Autor:
Xiaofeng Gu, Jeffrey Richman, Peter Langfelder, Nan Wang, Shasha Zhang, Monica Bañez-Coronel, Huei-Bin Wang, Lucia Yang, Lalini Ramanathan, Linna Deng, Chang Sin Park, Christopher R. Choi, Jeffrey P. Cantle, Fuying Gao, Michelle Gray, Giovanni Coppola, Gillian P. Bates, Laura P.W. Ranum, Steve Horvath, Christopher S. Colwell, X. William Yang
Publikováno v:
Neuron, vol 110, iss 7
In Huntington's disease (HD), the uninterrupted CAG repeat length, but not the polyglutamine length, predicts disease onset. However, the underlying pathobiology remains unclear. Here, we developed bacterial artificial chromosome (BAC) transgenic mic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b04693f7ac3c7c68110e9b998475b45c
https://escholarship.org/uc/item/52k97025
https://escholarship.org/uc/item/52k97025
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Ruth Warre, Sherri Thiele, Sheena Talwar, Marium Kamal, Tom H. Johnston, Sharon Wang, Doris Lam, Charlotte Lo, Charline S. Khademullah, Gillian Perera, Gabriela Reyes, Xuan Sherry Sun, Jonathan M. Brotchie, Joanne E. Nash
Publikováno v:
Neurobiology of Disease, Vol 41, Iss 3, Pp 591-604 (2011)
Objective: In Parkinson's disease, chronic striatal dopamine depletion results in over-activity and under-activity of the indirect and direct striatal output pathways respectively. In this study, we investigated changes in the function of glutamaterg
Externí odkaz:
https://doaj.org/article/db3035b775dc4d2ba0ef62f6d6d6637f
Optogenetic analysis of neuromuscular transmission in the colon of ChAT-ChR2-YFP BAC transgenic mice
Publikováno v:
Am J Physiol Gastrointest Liver Physiol
Propulsion of luminal content along the gut requires coordinated contractions and relaxations of gastrointestinal smooth muscles controlled by the enteric nervous system. Activation of excitatory motor neurons (EMNs) causes muscle contractions, where
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c2606713e9e048a5e2f7bf7467a8728
https://doi.org/10.1152/ajpgi.00089.2019
https://doi.org/10.1152/ajpgi.00089.2019