Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Babu V Sajesh"'
Autor:
Derek M van Pel, Irene J Barrett, Yoko Shimizu, Babu V Sajesh, Brent J Guppy, Tom Pfeifer, Kirk J McManus, Philip Hieter
Publikováno v:
PLoS Genetics, Vol 9, Iss 1, p e1003254 (2013)
Harnessing genetic differences between cancerous and noncancerous cells offers a strategy for the development of new therapies. Extrapolating from yeast genetic interaction data, we used cultured human cells and siRNA to construct and evaluate a synt
Externí odkaz:
https://doaj.org/article/7008e5b95da64f1da627f0bb212a729a
Publikováno v:
Acta Neuropathologica Communications, Vol 10, Iss 1, Pp 1-23 (2022)
Abstract Prion diseases are neurodegenerative disorders with long asymptomatic incubation periods, followed by a rapid progression of cognitive and functional decline culminating in death. The complexity of intercellular interactions in the brain is
Externí odkaz:
https://doaj.org/article/eb6491552a6b4206b5e093e1db4ba8c3
Autor:
Vinith Yathindranath, Nura Safa, Babu V. Sajesh, Kelly Schwinghamer, Magimairajan Issai Vanan, Rashid Bux, Daniel S. Sitar, Marshall Pitz, Teruna J. Siahaan, Donald W. Miller
Publikováno v:
Cancers, Vol 14, Iss 21, p 5179 (2022)
Spermidine/spermine N1-acetyltransferase 1 (SAT1) responsible for cell polyamine catabolism is overexpressed in glioblastoma multiforme (GB). Its role in tumor survival and promoting resistance towards radiation therapy has made it an interesting tar
Externí odkaz:
https://doaj.org/article/6f2d56000e024444a47c8c703a440565
Autor:
Babu V. Sajesh, Donald W. Miller, Ngoc H. On, Neal M. Davies, Brian M. Kopec, Magimairajan Issai Vanan, Pema-Tenzin Puno, Ted M. Lakowski, Han-Dong Sun, Ryan Lillico, Wei-Guang Wang, Samaa Alrushaid, Teruna J. Siahaan, Refaat Omar
Publikováno v:
Pharmaceutics, Vol 11, Iss 9, p 481 (2019)
Pharmaceutics
Volume 11
Issue 9
Pharmaceutics
Volume 11
Issue 9
The blood-brain barrier (BBB) poses a major obstacle by preventing potential therapeutic agents from reaching their intended brain targets at sufficient concentrations. While transient disruption of the BBB has been used to enhance chemotherapeutic e
Autor:
Babu V. Sajesh, Esther Hulleman, Demitre Serletis, Sherry Krawitz, Marc Del-bigio, C.J. Kazina, Ngoc H. On, Miller Donald, Magimairajan Issai Vanan
DIPG is the most common brainstem tumor in children and is uniformly fatal. The BBB is intact in DIPG and plays an active role in restricting the delivery of systemically administered therapies into the tumor. Recent studies have shown that SHH signa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da4844c011fed3666b9888e3429d5e0c
https://europepmc.org/articles/PMC6477213/
https://europepmc.org/articles/PMC6477213/
Autor:
Gary P. Kobinger, Shannon L. Hiebert, Stephanie A. Booth, Sarah J. Medina, Timothy F. Booth, Vanessa Zubach, Lee W. Goneau, Robert A. Kozak, Jessy A Slota, Anna Majer, Daniel R. Beniac, David Safronetz, Mia J. Biondi, Alberto Severini, Babu V Sajesh
Publikováno v:
Viruses; Volume 9; Issue 10; Pages: 297
Viruses
Viruses, Vol 9, Iss 10, p 297 (2017)
Viruses
Viruses, Vol 9, Iss 10, p 297 (2017)
The Zika virus (ZIKV) epidemic is an ongoing public health concern. ZIKV is a flavivirus reported to be associated with microcephaly, and recent work in animal models demonstrates the ability of the virus to cross the placenta and affect fetal brain
Autor:
Kirk J. McManus, Babu V. Sajesh
Publikováno v:
Oncotarget
// Babu V. Sajesh 1, 2 , Kirk J. McManus 1, 2 1 Department of Biochemistry and Medical Genetics, University of Manitoba, Winnipeg, Manitoba, Canada 2 Research Institute of Oncology and Hematology, Winnipeg, Manitoba, Canada Correspondence to: Kirk J.
Autor:
Babu V. Sajesh1 babu@cc.umanitoba.ca, Brent J. Guppy1 umguppyb@cc.umanitoba.ca, Kirk J. McManus1 mcmanusk@cc.umanitoba.ca
Publikováno v:
Cancers. Sep2013, Vol. 5 Issue 3, p739-761. 23p.
Autor:
Marc Remake, Jian-Xin Pu, Yan Wang, Marc Symons, Michael D. Taylor, Babu V. Sajesh, Han-Dong Sun, Magimairajan Issai Vanan, Rosamaria Ruggieri, Rui Zhong
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b9ede30f09318c520422937b40dcfd6
https://europepmc.org/articles/PMC4903605/
https://europepmc.org/articles/PMC4903605/
Publikováno v:
Cancer Metastasis-Biology and Treatment ISBN: 9783319121352
Colorectal cancer is the third leading cause of cancer-related deaths throughout the world. Surgery is effective against early stage tumors but advanced stage tumors lack an effective targeting strategy. For nearly 50 years, 5-fluorouracil has been t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4482d5c81662b563dd6fc803c27c2bd2
https://doi.org/10.1007/978-3-319-12136-9_9
https://doi.org/10.1007/978-3-319-12136-9_9