Výsledky vyhledávání - "Babu P. Mathew"

Traumatic Brain InjuryIn VivoandIn VitroContributes to Cerebral Vascular Dysfunction through Impaired Gap Junction Communication between Vascular Smooth Muscle Cells

Autor: Bridget E. Hawkins, Babu P. Mathew, Martin Mueller, Douglas S. DeWitt, Helen L. Hellmich, Guang Xiang Yu, Leoncio A. Vergara, Margaret A. Parsley, Donald S. Prough

Publikováno v: Journal of Neurotrauma. 31:739-748

Gap junctions (GJs) contribute to cerebral vasodilation, vasoconstriction, and, perhaps, to vascular compensatory mechanisms, such as autoregulation. To explore the effects of traumatic brain injury (TBI) on vascular GJ communication, we assessed GJ

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b0bca5e746d70f55f696c8b95205e0d
https://doi.org/10.1089/neu.2013.3187

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Peroxynitrite Reduces Vasodilatory Responses to Reduced Intravascular Pressure, Calcitonin Gene-Related Peptide, and Cromakalim in Isolated Middle Cerebral Arteries

Autor: Babu P. Mathew, Jennifer M. Chaisson, Donald S. Prough, Douglas S. DeWitt

Publikováno v: Journal of Cerebral Blood Flow & Metabolism. 21:253-261

Vasodilatory responses to progressive reductions in intravascular pressure or to calcitonin gene-related peptide (CGRP) or cromakalim were determined in rodent middle cerebral arteries (MCAs) before and after treatment with peroxynitrite (ONOO−). M

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30acb421525a8e6de5cf8ec1a8dea304
https://doi.org/10.1097/00004647-200103000-00009

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Role of calcitonin gene-related peptide (CGRP) in ovine burn and smoke inhalation injury

Autor: Atsumori Hamahata, David N. Herndon, Daniel L. Traber, Babu P. Mathew, Hal K. Hawkins, Lillian D. Traber, Robert A. Cox, Perenlei Enkhbaatar, Sam Jacob, Matthias Lange

Concomitant smoke inhalation trauma in burn patients is a serious medical problem. Previous investigations in our sheep model revealed that these injuries lead to significant airway hyperemia, enhanced pulmonary fluid extravasation, and severely impa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c65337075b03d85573679fab851e7d5
https://europepmc.org/articles/PMC2711784/

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Traumatic brain injury reduces myogenic responses in pressurized rodent middle cerebral arteries

Autor: Babu P. Mathew, Robert M. Bryan, Richard D. Bukoski, Donald S. Prough, Douglas S. DeWitt

Publikováno v: Journal of neurotrauma. 16(12)

Traumatic brain injury (TBI) reduces cerebral vascular pressure autoregulation in experimental animals and in patients. In order to understand better the mechanisms of impaired autoregulation, we measured myogenic responses to changes in intraluminal

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::676b91463d2c109ef0a0a8e273ba6208
https://pubmed.ncbi.nlm.nih.gov/10619196

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Resuscitation with hypertonic saline dextran improves cardiac function in vivo and ex vivo after burn injury in sheep

Autor: Michael A. Dubick, George C. Kramer, Paul J. Schenarts, Babu P. Mathew, Jureta W. Horton, Luiz F. Poli de Figueiredo, G. I. Elgjo

Publikováno v: Shock (Augusta, Ga.). 9(5)

In a 24 h, double-blind, prospective trial, we tested the hypothesis that two 4 mL/kg doses of hypertonic saline dextran (HSD; 7.5% NaCl/6% dextran 70) given in addition to isotonic fluid treatment would produce both immediate and sustained benefit f

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05c759890ed344b18b3a894cbc1cb330
https://pubmed.ncbi.nlm.nih.gov/9617889

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Myocardial depression by isoflurane is dependent on the underlying beta-adrenergic tone

Autor: Timothy A. Thurston, Babu P. Mathew

Publikováno v: Journal of cardiovascular pharmacology. 26(6)

Depression of myocardial contractility by muscarinic agonists is dependent on underlying beta-adrenergic tone. The negative inotropic effect of muscarinic agonists is enhanced by previous beta-adrenergic stimulation, an action that has been termed ac

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::775bc0d0b0e4c29e0f1bb21326b5fa68
https://pubmed.ncbi.nlm.nih.gov/8606520

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Thiopentone inhibits beta-adrenergic responses in myocardial tissue

Autor: Babu P. Mathew, Timothy A. Thurston

Publikováno v: Canadian journal of anaesthesia = Journal canadien d'anesthesie. 42(10)

The purpose of this study was to determine the importance of inhibition of beta-adrenergic function in thiopentone-induced myocardial depression. Using an isolated, electrically stimulated rat left atria model, contractile dose-response curves to thi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de8f232ef97880a167cc1c4da2afa472
https://pubmed.ncbi.nlm.nih.gov/8706206

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