Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Babu J. N. Reddy"'
Autor:
Dail E. Chapman, Babu J. N. Reddy, Bunchhin Huy, Matthew J. Bovyn, Stephen John S. Cruz, Zahraa M. Al-Shammari, Han Han, Wenqi Wang, Deanna S. Smith, Steven P. Gross
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
Dynein plays roles in vesicular, organelle, chromosomal and nuclear transport but so far it is unclear how dynein activity in cells is regulated. Here authors study several dynein cofactors and their role in force adaptation of dynein during lipid dr
Externí odkaz:
https://doaj.org/article/e6ccfec8ba164322ae51709ecaf1ad14
Autor:
Babu J. N. Reddy, Michelle Mattson, Caitlin L. Wynne, Omid Vadpey, Abdo Durra, Dail Chapman, Richard B. Vallee, Steven P. Gross
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-14 (2016)
Transport of large cargo through the cytoplasm can encounter physical impediments which should be overcome. Here the authors show that lipid droplets constrained by an optical trap respond with an increase in dynein-mediated force that is dependent o
Externí odkaz:
https://doaj.org/article/7e7d923186b3472a831167e71bd0f0c6
Autor:
Ibtissem Nabti, Babu J. N. Reddy, Rachid Rezgui, Wenqi Wang, Steven P. Gross, George T. Shubeita
Publikováno v:
Proceedings of the National Academy of Sciences. 119
Regulation of organelle transport by molecular motors along the cytoskeletal microtubules is central to maintaining cellular functions. Here, we show that the ubiquitous tau-related microtubule-associated protein 4 (MAP4) can bias the bidirectional t