Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Babu GA"'
Publikováno v:
Heliyon, Vol 10, Iss 23, Pp e40492- (2024)
Metabolic reprogramming is a crucial characteristic of cancer, allowing cancer cells to acquire metabolic properties that support their survival, immune evasion, and uncontrolled proliferation. Consequently, targeting cancer metabolism has become an
Externí odkaz:
https://doaj.org/article/30e32ba9d4184cb88e989cf1488bd774
Autor:
Jie Wang, Chunlin Wang, Anling Hu, Kunlin Yu, Yi Kuang, Babu Gajendran, Eldad Zacksenhaus, Klarke Michael Sample, Xiao Xiao, Wuling Liu, Yaacov Ben-David
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-15 (2024)
Abstract Background FLI1 is an oncogenic transcription factor that promotes diverse malignancies through mechanisms that are not fully understood. Herein, FLI1 is shown to regulate the expression of Ubiquitin Associated and SH3 Domain Containing A/B
Externí odkaz:
https://doaj.org/article/1e7a10e00166424bb547a8f8b2b0ef0d
Autor:
Krishnapriya M. Varier, Gou Dan, Xiaolong Li, Wuling Liu, Fei Jiang, Ke-Gang Linghu, Yanmei Li, Yaacov Ben-David, Nenling Zhang, Chaoda Xiao, Babu Gajendran, Xiangchun Shen
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Lymphoma positions as the fifth most common cancer, in the world, reporting remarkable deaths every year. Several promising strategies to counter this disease recently include utilizing small molecules that specifically target the lymphoma cellular p
Externí odkaz:
https://doaj.org/article/50dcc2e6f69a4a239a83c482dee0e407
Publikováno v:
Energy Reports, Vol 9, Iss , Pp 3508-3530 (2023)
Cost effective modes of transport keeping in conjunction with sustainable outlooks for the future have ensured new technologies and initiatives being taken across the globe. Lighter electric vehicles including two-wheelers or scooters have risen in p
Externí odkaz:
https://doaj.org/article/95b8c20e1b5845dca9c3e018e2108832
Publikováno v:
Physical Review Research, Vol 6, Iss 3, p 033015 (2024)
Adhesives require molecular contact, which is governed by roughness, modulus, and load. Here, we measured adhesion for stiff glassy polymer layers of varying thickness on top of a soft elastomer with rough substrates. We found that a 90-nm-thick PMMA
Externí odkaz:
https://doaj.org/article/952f945013fd4d9cbebc8e7a37e7b8c2
Autor:
Jian Gao, Jifen Hu, Fang Yu, Chunlin Wang, Danmei Sheng, Wuling Liu, Anling Hu, Kunling Yu, Xiao Xiao, Yi Kuang, Eldad Zacksenhaus, Babu Gajendran, Yaacov Ben-David
Publikováno v:
BMC Cancer, Vol 23, Iss 1, Pp 1-12 (2023)
Abstract Background Lovastatin, an HMG-CoA inhibitor and an effective cholesterol lowering drug, exhibits anti-neoplastic activity towards several types of cancer, although the underlying mechanism is still not fully understood. Herein, we investigat
Externí odkaz:
https://doaj.org/article/951e24cdb29a4642858a3cbf83b27f66
Autor:
Jingrui Song, Kun Yang, Babu Gajendran, Krishnapriya M. Varier, Wenxue Li, Qin Liu, Qing Rao, Yubing Hang, Xiangchun Shen, Sheng Liu, Lei Huang, Mei Xu, Yanmei Li
Publikováno v:
Frontiers in Bioscience-Landmark, Vol 29, Iss 4, p 163 (2024)
Background: Glucocorticoids (GCs) are commonly used as the primary chemotherapy for lymphoid malignancies, including acute lymphoblastic leukemia (ALL). However, the development of GC resistance limits their prolonged use. Methods: In this study, we
Externí odkaz:
https://doaj.org/article/084c3e5d4764438682cdb93a3de62dec
Autor:
Anling Hu, Jian Gao, Krishnapriya M. Varier, Babu Gajendran, Fei Jiang, Wuling Liu, Chunlin Wang, Xiao Xiao, Yanmei Li, Eldad Zacksenhaus, Sajjad Ali, Yaacov Ben-David
Publikováno v:
Cell Death Discovery, Vol 8, Iss 1, Pp 1-9 (2022)
Abstract The pyrimido-indole derivative UM171 promotes human Hematopoietic Stem Cells Expansion (HSCE), but its impact on leukemia is not known. Herein, we show in a mouse model of erythroleukemia that UM171 strongly suppresses leukemia progression.
Externí odkaz:
https://doaj.org/article/e8c6955993c6426ca9d9881906959fe9
Autor:
Lei Huang, Yanrong Zeng, Fei Li, Xiuyan Zheng, Qing Rao, Babu Gajendran, Krishnapriya M. Varier, Tong Peng, Lin Tang
Publikováno v:
Journal of Functional Foods, Vol 108, Iss , Pp 105715- (2023)
Previous reports have suggested that Idesia polycarpa Maxim. (I. polycarpa) fruits possess properties for the prevention and treatment of non-alcoholic fatty liver disease (NAFLD), owing to its lipid-lowering and anti-oxidant activities. In this stud
Externí odkaz:
https://doaj.org/article/85212b5a317a41bfb71da41c3f4600d4
Publikováno v:
E3S Web of Conferences, Vol 472, p 02010 (2024)
Image inpainting can be used to fix broken images and get rid of distracting elements. In exemplar based methods, patch priority computation and exemplar patch selection are crucial to the success of image inpainting technique. The dropping effect oc
Externí odkaz:
https://doaj.org/article/7b6db7c1876e4d7d8db70788f6b79b0d