Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Babs O. Fabriek"'
Autor:
C Mircea S Tesileanu, Sotirios Michaleas, Rocio Gonzalo Ruiz, Segundo Mariz, Babs O Fabriek, Paula B van Hennik, Jutta Dedorath, Bruna Dekic, Christoph Unkrig, Andreas Brandt, Janet Koenig, Harald Enzmann, Julio Delgado, Francesco Pignatti
Publikováno v:
The Oncologist.
Asciminib is an allosteric high-affinity tyrosine kinase inhibitor (TKI) of the BCR-ABL1 protein kinase. This kinase is translated from the Philadelphia chromosome in chronic myeloid leukemia (CML). Marketing authorization for asciminib was granted o
Autor:
Esther K. Zondervan-van den Beuken, Babs O. Fabriek, Inge Nelissen, Anja J. Boumeester, Anita C. A. Dankers, Ingeborg M. Kooter, Rob J. Vandebriel, C. Frieke Kuper, Peter C. Tromp, Mariska Gröllers-Mulderij
Publikováno v:
Journal of Applied Toxicology. 38:160-171
Exposure of humans to metal oxide nanoparticles (NPs) occurs mainly via air, and inhaled metal oxide NPs may generate inflammation. The aim of this study was to investigate the proinflammatory potential of six metal oxide NPs (CeO2, Mn2O3, CuO, ZnO,
Autor:
Bernard M. J. Uitdehaag, Timo K. van den Berg, Rianka P. M. Vloet, Roeland Hanemaaijer, Charlotte E. Teunissen, Holger Jon Møller, Babs O. Fabriek, Christine D. Dijkstra, Lisa van Winsen
Publikováno v:
Journal of Neuroimmunology, 187(1-2), 179-86. Elsevier
Journal of neuroimmunology, 187(1-2), 179-186. Elsevier
Fabriek, B O, Møller, H J, Vloet, R P M, van Winsen, L M, Hanemaaijer, R, Teunissen, C E, Uitdehaag, B M J, van den Berg, T K & Dijkstra, C D 2007, ' Proteolytic shedding of the macrophage scavenger receptor CD163 in multiple sclerosis. ', Journal of Neuroimmunology, vol. 187, no. 1-2, pp. 179-86 . https://doi.org/10.1016/j.jneuroim.2007.04.016
Fabriek, B O, Møller, H J, Vloet, R P M, van Winsen, L M, Hanemaaijer, R, Teunissen, C E, Uitdehaag, B M J, van den Berg, T K & Dijkstra, C D 2007, ' Proteolytic shedding of the macrophage scavenger receptor CD163 in multiple sclerosis ', Journal of Neuroimmunology, vol. 187, no. 1-2, pp. 179-86 . https://doi.org/10.1016/j.jneuroim.2007.04.016
Journal of neuroimmunology, 187(1-2), 179-186. Elsevier
Fabriek, B O, Møller, H J, Vloet, R P M, van Winsen, L M, Hanemaaijer, R, Teunissen, C E, Uitdehaag, B M J, van den Berg, T K & Dijkstra, C D 2007, ' Proteolytic shedding of the macrophage scavenger receptor CD163 in multiple sclerosis. ', Journal of Neuroimmunology, vol. 187, no. 1-2, pp. 179-86 . https://doi.org/10.1016/j.jneuroim.2007.04.016
Fabriek, B O, Møller, H J, Vloet, R P M, van Winsen, L M, Hanemaaijer, R, Teunissen, C E, Uitdehaag, B M J, van den Berg, T K & Dijkstra, C D 2007, ' Proteolytic shedding of the macrophage scavenger receptor CD163 in multiple sclerosis ', Journal of Neuroimmunology, vol. 187, no. 1-2, pp. 179-86 . https://doi.org/10.1016/j.jneuroim.2007.04.016
The scavenger receptor CD163 is selectively expressed on tissue macrophages and human monocytes. CD163 has been implicated to play a role in the clearance of hemoglobin and in the regulation of cytokine production by macrophages. Membrane CD163 can b
Autor:
Babs O. Fabriek, Christine D. Dijkstra, Corline J.A. De Groot, Ian Galea, Elise S. van Haastert, Ed D. Döpp, Machteld M. J. Polfliet, Paul van der Valk, Timo K. van den Berg, Michel M Van Den Heuvel
Publikováno v:
Fabriek, B O, Van Haastert, E S, Galea, I, Polfliet, M M J, Döpp, E D, Van Den Heuvel, M M, Van Den Berg, T K, De Groot, C J A, Van Der Valk, P & Dijkstra, C D 2005, ' CD163-positive perivascular macrophages in the human CNS express molecules for antigen recognition and presentation ', GLIA, vol. 51, no. 4, pp. 297-305 . https://doi.org/10.1002/glia.20208
GLIA, 51(4), 297-305. John Wiley and Sons Inc.
Glia, 51(4), 297-305. John Wiley and Sons Inc.
GLIA, 51(4), 297-305. John Wiley and Sons Inc.
Glia, 51(4), 297-305. John Wiley and Sons Inc.
Perivascular macrophages (PVM) constitute a subpopulation of resident macrophages in the central nervous system (CNS) that by virtue of their strategic location at the blood-brain barrier potentially lend themselves to a variety of important function
Autor:
Christine D. Dijkstra, Jon D. Laman, Charlotte E. Teunissen, Jack N.P. Zwemmer, Chris H. Polman, Babs O. Fabriek, Jonas A. Castelijns
Publikováno v:
Journal of Neuroimmunology, 161(1-2), 190-194. Elsevier
Fabriek, B O, Zwemmer, J N, Teunissen, C E, Dijkstra, C D, Polman, C H, Laman, JD & Castelijns, J A 2005, ' In vivo detection of myelin proteins in cervical lymph nodes of MS patients using ultrasound-guided fine-needle aspiration cytology ', Journal of Neuroimmunology, vol. 161, no. 1-2, pp. 190-194 . https://doi.org/10.1016/j.jneuroim.2004.12.018
Fabriek, B O, Zwemmer, J N, Teunissen, C E, Dijkstra, C D, Polman, C H, Laman, JD & Castelijns, J A 2005, ' In vivo detection of myelin proteins in cervical lymph nodes of MS patients using ultrasound-guided fine-needle aspiration cytology ', Journal of Neuroimmunology, vol. 161, no. 1-2, pp. 190-194 . https://doi.org/10.1016/j.jneuroim.2004.12.018
Cervical lymph nodes (CLN) have been described to be the first lymphoid draining site of the brain. In this study we used ultrasound guided fine needle aspiration cytology (USgFNAC) to obtain cells, in vivo, from non-enlarged CLN of multiple sclerosi
Autor:
George G. J. M. Kuiper, Jack L. Leonard, Unga A. Unmehopa, Dick F. Swaab, Babs O. Fabriek, Edith C. H. Friesema, Theo J. Visser, Wilmar M. Wiersinga, Eric Fliers, Anneke Alkemade
Publikováno v:
The Journal of clinical endocrinology and metabolism, 90, 4322-4334. The Endocrine Society
Journal of Clinical Endocrinology and Metabolism, 90(7), 4322-4334. Endocrine Society
Journal of clinical endocrinology and metabolism, 90(7), 4322-4334. The Endocrine Society
Journal of Clinical Endocrinology and Metabolism, 90(7), 4322-4334. Endocrine Society
Journal of clinical endocrinology and metabolism, 90(7), 4322-4334. The Endocrine Society
CONTEXT: Recent findings point to an increasing number of hypothalamic proteins involved in the central regulation of thyroid hormone feedback. The functional neuroanatomy of these proteins in the human hypothalamus is largely unknown at present. OBJ
Autor:
N. Harry Hendrikse, Hugo Sandman, Birgit C. P. Koch, Catherijne A. J. Knibbe, Dick Tibboel, Albert D. Windhorst, Dimitri Grossouw, Miriam G. Mooij, Paul J. J. M. Janssen, Edwin Spaans, Wouter H. J. Vaes, Babs O. Fabriek, Esther van Duijn, Lidwien M. Hanff, Saskia N. de Wildt
Publikováno v:
Mooij, M G, van Duijn, E, Knibbe, C A J, Windhorst, A D, Hendrikse, N H, Vaes, W H J, Spaans, E, Fabriek, B O, Sandman, H, Grossouw, D, Hanff, L M, Janssen, P J J M, Koch, B C P, Tibboel, D & De Wildt, S N 2014, ' Pediatric Microdose Study of [C-14] Paracetamol to Study Drug Metabolism Using Accelerated Mass Spectrometry: Proof of Concept ', Clinical Pharmacokinetics, vol. 53, no. 11, pp. 1045-1051 . https://doi.org/10.1007/s40262-014-0176-8
Clinical Pharmacokinetics, 53(11), 1045-1051. Adis
Clinical Pharmacokinetics
Clinical Pharmacokinetics, 53(11), 1045-1051. Adis International Ltd
Clinical Pharmacokinetics, 53(11), 1045-1051. Adis
Clinical Pharmacokinetics
Clinical Pharmacokinetics, 53(11), 1045-1051. Adis International Ltd
Background Pediatric drug development is hampered by practical, ethical, and scientific challenges. Microdosing is a promising new method to obtain pharmacokinetic data in children with minimal burden and minimal risk. The use of a labeled oral micro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b562019fe99031ca8777569b7598625
https://research.vumc.nl/en/publications/476c76db-1e92-4d56-ad15-256dd3ed20ee
https://research.vumc.nl/en/publications/476c76db-1e92-4d56-ad15-256dd3ed20ee
Autor:
Klemens Ruprecht, Hervé Perron, Mario Clerici, Alois B. Lang, Roberta Mancuso, Patrice Morand, Hans-Peter Hartung, Pablo Villoslada, Corinne Bernard, Cécile Deluen, Raphaëlle Germi, Sébastien Marcel, Ilias Stefas, Giannina Arru, Paul Van-Der-Valk, Rosella Cavaretta, Alain Créange, Peter Rieckmann, Stefano Sotgiu, Francisco Veas, Jean Pelletier, Raphaël Faucard, Jack Van-Horssen, José Boucraut, Claire Gerdil, Domenico Caputo, Marina Saresella, Laurent Farinelli, Michel Chofflon, Marta Garcia-Montojo, Babs O. Fabriek
Publikováno v:
Multiple Sclerosis (Houndmills, Basingstoke, England)
Perron, H, Germi, R, Bernard, C, Garcia-Montojo, M, Deluen, C, Farinelli, L, Faucard, R, Veas, F, Stefas, I, Fabriek, B O, van Horssen, J, van der Valk, P, Gerdil, C, Mancuso, R, Saresella, M, Clerici, M, Marcel, S, Creange, A, Cavaretta, R, Caputo, D, Arru, G, Morand, P, Lang, A B, Sotgiu, S, Ruprecht, K, Rieckmann, P, Villoslada, P, Chofflon, M, Boucraut, J, Pelletier, J & Hartung, H P 2012, ' Human endogenous retrovirus type W envelope expression in blood and brain cells provides new insights into multiple sclerosis disease ', Multiple Sclerosis, vol. 18, no. 12, pp. 1721-1736 . https://doi.org/10.1177/1352458512441381
Multiple Sclerosis, 18(12), 1721-1736. SAGE Publications Ltd
Multiple Sclerosis Journal
Multiple Sclerosis Journal, SAGE Publications, 2012, 18 (12), pp.1721-36. ⟨10.1177/1352458512441381⟩
Multiple Sclerosis Journal, 2012, 18 (12), pp.1721-36. ⟨10.1177/1352458512441381⟩
Perron, H, Germi, R, Bernard, C, Garcia-Montojo, M, Deluen, C, Farinelli, L, Faucard, R, Veas, F, Stefas, I, Fabriek, B O, van Horssen, J, van der Valk, P, Gerdil, C, Mancuso, R, Saresella, M, Clerici, M, Marcel, S, Creange, A, Cavaretta, R, Caputo, D, Arru, G, Morand, P, Lang, A B, Sotgiu, S, Ruprecht, K, Rieckmann, P, Villoslada, P, Chofflon, M, Boucraut, J, Pelletier, J & Hartung, H P 2012, ' Human endogenous retrovirus type W envelope expression in blood and brain cells provides new insights into multiple sclerosis disease ', Multiple Sclerosis, vol. 18, no. 12, pp. 1721-1736 . https://doi.org/10.1177/1352458512441381
Multiple Sclerosis, 18(12), 1721-1736. SAGE Publications Ltd
Multiple Sclerosis Journal
Multiple Sclerosis Journal, SAGE Publications, 2012, 18 (12), pp.1721-36. ⟨10.1177/1352458512441381⟩
Multiple Sclerosis Journal, 2012, 18 (12), pp.1721-36. ⟨10.1177/1352458512441381⟩
Perron, Herve Germi, Raphaelle Bernard, Corinne Garcia-Montojo, Marta Deluen, Cecile Farinelli, Laurent Faucard, Raphael Veas, Francisco Stefas, Ilias Fabriek, Babs O Van-Horssen, Jack Van-der-Valk, Paul Gerdil, Claire Mancuso, Roberta Saresella, Mar
Autor:
Antoon J. M. Ligtenberg, Kamran Nazmi, Babs O. Fabriek, Karin Schornagel, Robin van Bruggen, Dong Mei Deng, Timo K. van den Berg, Christine D. Dijkstra, Rianka P. M. Vloet
Publikováno v:
Blood, 113(4), 887-892. American Society of Hematology
Fabriek, B O, van Bruggen, R, Deng, D M, Ligtenberg, A J M, Nazmi, K, Schornagel, K, Vloet, R P M, Dijkstra, C D & van den Berg, T K 2009, ' The macrophage scavenger receptor CD163 functions as an innate immune sensor for bacteria ', Blood, vol. 113, no. 4, pp. 887-892 . https://doi.org/10.1182/blood-2008-07-167064
Blood, 4, 113, 887-892
Fabriek, B O, van Bruggen, R, Deng, D M, Ligtenberg, A J M, Nazmi, K, Schornagel, K, Vloet, R P M, Dijkstra, C D & van den Berg, T K 2009, ' The macrophage scavenger receptor CD163 functions as an innate immune sensor for bacteria ', Blood, vol. 113, no. 4, pp. 887-892 . https://doi.org/10.1182/blood-2008-07-167064
Blood, 4, 113, 887-892
The plasma membrane glycoprotein re- ceptor CD163 is a member of the scaven- ger receptor cystein-rich (SRCR) super- family class B that is highly expressed on resident tissue macrophages in vivo. Pre- viously, the molecule has been shown to act as a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65ad4f5b7a2203d5178c9c1aa72d9d91
https://research.vu.nl/en/publications/b5bcbd81-3bf0-4fa3-b564-794664e5e56d
https://research.vu.nl/en/publications/b5bcbd81-3bf0-4fa3-b564-794664e5e56d
Autor:
Rianka P. M. Vloet, Antoon J M Ligtenberg, Babs O. Fabriek, Christien D. Dijkstra, Lehn K. Weaver, Kenjiro Matsuno, Machteld M. J. Polfliet, Christiaan Geest, Timo K. van den Berg, Søren K. Moestrup, Roel C. van der Schors
Publikováno v:
Fabriek, B O, Polfliet, M M J, Vloet, R P M, van der Schors, R C, Ligtenberg, A J M, Weaver, L K, Geest, C, Matsuno, K, Moestrup, S K, Dijkstra, C D & van den Berg, T K 2007, ' The macrophage CD163 surface glycoprotein is an erythroblast adhesion receptor ', Blood, vol. 109, pp. 5223-5229 . https://doi.org/10.1182/blood-2006-08-036467
Blood, 109(12), 5223-5229. American Society of Hematology
Blood, 109, 5223-5229. American Society of Hematology
Fabriek, B O, Polfliet, M M J, Vloet, R P M, van der Schors, R C, Ligtenberg, A J M, Weaver, L K, Geest, C, Matsuno, K, Moestrup, S K, Dijkstra, C D & van den Berg, T K 2007, ' The macrophage CD163 surface glycoprotein is an erythroblast adhesion receptor ', Blood, vol. 109, no. 12, pp. 5223-9 . https://doi.org/10.1182/blood-2006-08-036467
Blood, 109(12), 5223-9. American Society of Hematology
Blood, 109(12), 5223-5229. American Society of Hematology
Blood, 109, 5223-5229. American Society of Hematology
Fabriek, B O, Polfliet, M M J, Vloet, R P M, van der Schors, R C, Ligtenberg, A J M, Weaver, L K, Geest, C, Matsuno, K, Moestrup, S K, Dijkstra, C D & van den Berg, T K 2007, ' The macrophage CD163 surface glycoprotein is an erythroblast adhesion receptor ', Blood, vol. 109, no. 12, pp. 5223-9 . https://doi.org/10.1182/blood-2006-08-036467
Blood, 109(12), 5223-9. American Society of Hematology
Erythropoiesis occurs in erythroblastic islands, where developing erythroblasts closely interact with macrophages. The adhesion molecules that govern macrophage-erythroblast contact have only been partially defined. Our previous work has implicated t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9c88bc920ed04daf6a169add2381474
https://research.vu.nl/en/publications/2f3c498f-a102-440a-ae96-3acc42b184df
https://research.vu.nl/en/publications/2f3c498f-a102-440a-ae96-3acc42b184df