Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Babina Sanjel"'
Publikováno v:
British Journal of Pharmacology. 179:2193-2207
Background and purpose Glucosylsphingosine (GS), an endogenous sphingolipid, is highly accumulated in the epidermis of patients with atopic dermatitis (AD) due to abnormal ceramide metabolism. More importantly, GS can evoke scratching behaviors. Howe
Publikováno v:
Life Sciences. 325:121786
Autor:
Babina Sanjel, Won-Sik Shim
Publikováno v:
Biochemical pharmacology. 203
Atopic dermatitis (AD) is a dermatological disease accompanied by dry and cracked skin with severe pruritus. Although various therapeutic strategies have been introduced to alleviate AD, it remains challenging to cure the disorder. To achieve such a
Publikováno v:
Br J Pharmacol
BACKGROUND AND PURPOSE: Glucosylsphingosine (GS), an endogenous sphingolipid, is highly accumulated in the epidermis of patients with atopic dermatitis (AD) due to abnormal ceramide metabolism. More importantly, GS can evoke scratching behaviours. Ho
Autor:
Won-Sik Shim, Babina Sanjel
Publikováno v:
Biochimica et biophysica acta. Molecular basis of disease. 1866(12)
Cholestasis, a condition characterized by an abnormal decrease in bile flow, is accompanied by various symptoms such as pruritus. Although cholestatic pruritus is a prominent condition, its precise mechanisms have largely been elusive. Recently, adva
Publikováno v:
Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-13 (2019)
Scientific Reports, Vol 9, Iss 1, Pp 1-13 (2019)
Pruritus is an unexpected symptom observed in cholestasis and its mechanism is still unclear. Here, we show that bovine adrenal medulla (BAM) 8–22, an endogenous itch-inducing peptide, could be involved in cholestatic pruritus. It was found that bi
Autor:
Youn Kyoung Son, Hye Yoon Park, Bo Hyun Kim, Sun Yeou Kim, Babina Sanjel, Won-Sik Shim, KyoHee Cho, Wook-Joo Lee
Publikováno v:
Physiologybehavior. 210
Pyrus ussuriensis Maxim. commonly known as "Sandolbae" in Korean is a pear tree widely distributed across East Asia. Recent studies indicate that P. ussuriensis Maxim. leaves (PUL) have antipruritic effects. This study aimed to determine the effects