Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Babette, Dieringer"'
Autor:
Leslie Elsner, Lisanne Heimann, Anja Geisler, Babette Dieringer, Klaus-Peter Knoch, Luisa Hinze, Karin Klingel, Michel Solimena, Jens Kurreck, Henry Fechner
Publikováno v:
Biological Procedures Online, Vol 26, Iss 1, Pp 1-16 (2024)
Abstract Background The efficacy of oncolytic viruses (OV) in cancer treatment depends on their ability to successfully infect and destroy tumor cells. However, patients’ tumors vary, and in the case of individual insensitivity to an OV, therapeuti
Externí odkaz:
https://doaj.org/article/12073503249b4b00bb4d7853be5b2933
Autor:
Anja Geisler, Babette Dieringer, Leslie Elsner, Karin Klingel, Robert Klopfleisch, Hans-Peter Vornlocher, Jens Kurreck, Henry Fechner
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 32, Iss , Pp 923-936 (2023)
RNA interference has demonstrated its potential as an antiviral therapy for treatment of human adenovirus (hAd) infections. The only existing viral vector-based system for delivery of anti-adenoviral artificial microRNAs available for in vivo use, ho
Externí odkaz:
https://doaj.org/article/8f857671448d4f67b3c18507d9e19145
Autor:
Ahmet Hazini, Babette Dieringer, Karin Klingel, Markian Pryshliak, Anja Geisler, Dennis Kobelt, Ole Daberkow, Jens Kurreck, Sophie van Linthout, Henry Fechner
Publikováno v:
Viruses, Vol 13, Iss 10, p 1918 (2021)
The coxsackievirus B3 strain PD-0 has been proposed as a new oncolytic virus for the treatment of colorectal carcinoma. Here, we generated a cDNA clone of PD-0 and analyzed the virus PD-H, newly generated from this cDNA, in xenografted and syngenic m
Externí odkaz:
https://doaj.org/article/8d54fbe139e848008b4fb87dcb4632ec
Autor:
Franziska Jönsson, Jürgen Eberle, Sina Zarif, Florian Kreppel, Ahmet Hazini, Babette Dieringer, Jens Kurreck, Beatrice Tolksdorf, Henry Fechner
Publikováno v:
Journal of Molecular Medicine (Berlin, Germany)
Abstract Arming of oncolytic viruses with tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) has been shown as a viable approach to increase the antitumor efficacy in melanoma. However, melanoma cells may be partially or completely resis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::958ad7aaf4ad855e2922302f0f42b22e
https://doi.org/10.1007/s00109-021-02081-3
https://doi.org/10.1007/s00109-021-02081-3
Autor:
Beatrice Tolksdorf, Henry Fechner, Jens Kurreck, Kathleen Pappritz, Michele Solimena, Antje Beling, Lisanne Heimann, Klaus-Peter Knoch, Babette Dieringer, Markian Pryshliak, Muhammad El-Shafeey, Ahmet Hazini, Karin Klingel
Publikováno v:
Human Gene Therapy. 32:216-230
Coxsackievirus B3 (CVB3) has strong oncolytic activity in colorectal carcinoma but it also infects the pancreas and the heart. To improve the safety of the virus, here we investigated whether pancreas and cardiac toxicity can be prevented by insertio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cda4079d3bcbcf1fc72bb0dcc9ff7c0a
https://doi.org/10.1089/hum.2020.228
https://doi.org/10.1089/hum.2020.228
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2521
The members of the picornavirus family include various viruses which, due to their impressive oncolytic activity, have the potential to be used for the treatment of cancer. However, the replication of these oncolytic viruses (OV) is not limited to tu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::cb7c8fac926f9a5453cdc033bac62268
https://pubmed.ncbi.nlm.nih.gov/35733003
https://pubmed.ncbi.nlm.nih.gov/35733003
Publikováno v:
Methods in Molecular Biology ISBN: 9781071624401
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::867dd259f1b4511600a96d1972bb84a3
https://doi.org/10.1007/978-1-0716-2441-8_14
https://doi.org/10.1007/978-1-0716-2441-8_14
Autor:
J Lin, Dirk Lassner, Kathleen Pappritz, Klaus Peter Knoch, Fengquan Dong, Jens Kurreck, Luisa Hinze, Michele Solimena, Carsten Tschöpe, Sophie Van Linthout, Ziya Kaya, Muhammad El-Shafeey, Karin Klingel, Markian Pryshliak, Robert Klopfleisch, Babette Dieringer, Katrin Schaar, Ahmet Hazini, Henry Fechner, Sandra Pinkert, Antje Beling
Publikováno v:
Cardiovasc. Res. 116, 1756-1766 (2020)
Cardiovasc Res
Cardiovasc Res
Aims The coxsackievirus B3 (CVB3) mouse myocarditis model is the standard model for investigation of virus-induced myocarditis but the pancreas, rather than the heart, is the most susceptible organ in mouse. The aim of this study was to develop a CVB
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ab29588702faa7003487d5fa9bf82f0
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=57883
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=57883
Autor:
Karin Klingel, Carsten Tschöpe, Babette Dieringer, Jens Kurreck, Antje Beling, Robert Klopfleisch, Sandra Pinkert, Sophie Van Linthout, Konstantinos Savvatis, Henry Fechner, Markian Pryshliak
Publikováno v:
Circulation. Heart failure. 12(11)
Background: Coxsackie-B-viruses (CVB) are frequent causes of acute myocarditis and dilated cardiomyopathy, but an effective antiviral therapy is still not available. Previously, we and others have demonstrated that treatment with an engineered sCAR-F
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f0abddf0afed39c50c3321cf0693e2f
https://pubmed.ncbi.nlm.nih.gov/31718319
https://pubmed.ncbi.nlm.nih.gov/31718319
Autor:
Babette Dieringer, Michele Solimena, Beatrice Tolksdorf, Jens Kurreck, Markian Pryshliak, Sandra Pinkert, Henry Fechner, Ahmet Hazini, Klaus Peter Knoch
Publikováno v:
FEBS Lett. 594, 763-775 (2019)
FEBS Letters
FEBS Letters
Coxsackievirus B3 (CVB3) has potential as a new oncolytic agent for the treatment of cancer but can induce severe pancreatitis. Here, we inserted target sequences of the microRNA miR-375 (miR-375TS) into the 5′ terminus of the polyprotein encoding
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ffeecb5e038c38ca4cabbb32d7779d8
https://pubmed.ncbi.nlm.nih.gov/31643074
https://pubmed.ncbi.nlm.nih.gov/31643074