Multimodal surveillance of SARS-CoV-2 at a university enables development of a robust outbreak response framework.

Autor: Petros BA; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA; Harvard-MIT Program in Health Sciences and Technology, Cambridge, MA 02139, USA; Harvard/MIT MD-PhD Program, Boston, MA 02115, USA; Systems, Synthetic, and Quantitative Biology PhD Program, Department of Systems Biology, Harvard Medical School, Boston, MA 02115, USA., Paull JS; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA; Systems, Synthetic, and Quantitative Biology PhD Program, Department of Systems Biology, Harvard Medical School, Boston, MA 02115, USA. Electronic address: jpaull@broadinstitute.org., Tomkins-Tinch CH; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA; Department of Organismic and Evolutionary Biology, Harvard University, Cambridge, MA 02138, USA. Electronic address: tomkinsc@broadinstitute.org., Loftness BC; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA; Department of Computer Science and Engineering, Colorado Mesa University, Grand Junction, CO 81501, USA; Complex Systems and Data Science PhD Program, University of Vermont, Burlington, VT 05405, USA; Vermont Complex Systems Center, University of Vermont, Burlington, VT 05405, USA. Electronic address: bloftnes@broadinstitute.org., DeRuff KC; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA., Nair P; Howard Hughes Medical Institute, Chevy Chase, MD 20815, USA., Gionet GL; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA., Benz A; Degree Analytics, Inc., Austin, TX 78758, USA., Brock-Fisher T; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA., Hughes M; Colorado Mesa University, Grand Junction, CO 81501, USA., Yurkovetskiy L; Program in Molecular Medicine, University of Massachusetts Chan Medical School, Worcester, MA 01655, USA., Mulaudzi S; Harvard Program in Bioinformatics and Integrative Genomics, Harvard Medical School, Boston, MA 02115, USA., Leenerman E; Colorado Mesa University, Grand Junction, CO 81501, USA., Nyalile T; Program in Molecular Medicine, University of Massachusetts Chan Medical School, Worcester, MA 01655, USA., Moreno GK; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA., Specht I; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA., Sani K; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA., Adams G; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA., Babet SV; Department of Civil, Environmental, and Architectural Engineering, University of Colorado, Boulder, CO 80309, USA., Baron E; COVIDCheck Colorado, LLC, Denver, CO 80202, USA., Blank JT; Colorado Mesa University, Grand Junction, CO 81501, USA., Boehm C; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA; Princeton University Molecular Biology Department, Princeton, NJ 08544, USA., Botti-Lodovico Y; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA., Brown J; Colorado Mesa University, Grand Junction, CO 81501, USA., Buisker AR; Colorado Mesa University, Grand Junction, CO 81501, USA., Burcham T; Fathom Information Design, Boston, MA 02114, USA., Chylek L; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA., Cronan P; Fathom Information Design, Boston, MA 02114, USA., Dauphin A; Program in Molecular Medicine, University of Massachusetts Chan Medical School, Worcester, MA 01655, USA., Desreumaux V; Department of Civil, Environmental, and Architectural Engineering, University of Colorado, Boulder, CO 80309, USA., Doss M; Warrior Diagnostics, Inc., Loveland, CO 80538, USA., Flynn B; Colorado Mesa University, Grand Junction, CO 81501, USA., Gladden-Young A; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA., Glennon O; Fathom Information Design, Boston, MA 02114, USA., Harmon HD; Colorado Mesa University, Grand Junction, CO 81501, USA., Hook TV; Department of Civil, Environmental, and Architectural Engineering, University of Colorado, Boulder, CO 80309, USA., Kary A; Department of Biological Sciences, Colorado Mesa University, Grand Junction, CO 81501, USA., King C; Department of Mathematics and Statistics, Colorado Mesa University, Grand Junction, CO 81501, USA., Loreth C; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA., Marrs L; Fathom Information Design, Boston, MA 02114, USA., McQuade KJ; Department of Biological Sciences, Colorado Mesa University, Grand Junction, CO 81501, USA., Milton TT; Department of Civil, Environmental, and Architectural Engineering, University of Colorado, Boulder, CO 80309, USA., Mulford JM; Department of Biological Sciences, Colorado Mesa University, Grand Junction, CO 81501, USA., Oba K; Fathom Information Design, Boston, MA 02114, USA., Pearlman L; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA., Schifferli M; Fathom Information Design, Boston, MA 02114, USA., Schmidt MJ; Colorado Mesa University, Grand Junction, CO 81501, USA., Tandus GM; Department of Civil, Environmental, and Architectural Engineering, University of Colorado, Boulder, CO 80309, USA., Tyler A; Colorado Mesa University, Grand Junction, CO 81501, USA., Vodzak ME; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA., Krohn Bevill K; Department of Computer Science and Engineering, Colorado Mesa University, Grand Junction, CO 81501, USA., Colubri A; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA; University of Massachusetts Medical School, Worcester, MA 01655, USA., MacInnis BL; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA., Ozsoy AZ; Department of Biological Sciences, Colorado Mesa University, Grand Junction, CO 81501, USA., Parrie E; COVIDCheck Colorado, LLC, Denver, CO 80202, USA., Sholtes K; Department of Computer Science and Engineering, Colorado Mesa University, Grand Junction, CO 81501, USA; Department of Civil, Environmental, and Architectural Engineering, University of Colorado, Boulder, CO 80309, USA., Siddle KJ; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA; Department of Organismic and Evolutionary Biology, Harvard University, Cambridge, MA 02138, USA., Fry B; Fathom Information Design, Boston, MA 02114, USA., Luban J; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA; Program in Molecular Medicine, University of Massachusetts Chan Medical School, Worcester, MA 01655, USA; Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, Worcester, MA 01655, USA; Massachusetts Consortium on Pathogen Readiness, Boston, MA 02115, USA., Park DJ; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA., Marshall J; Colorado Mesa University, Grand Junction, CO 81501, USA., Bronson A; Physician Assistant Program, Department of Kinesiology, Colorado Mesa University, Grand Junction, CO 81501, USA., Schaffner SF; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA., Sabeti PC; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA; Department of Organismic and Evolutionary Biology, Harvard University, Cambridge, MA 02138, USA; Howard Hughes Medical Institute, Chevy Chase, MD 20815, USA; Massachusetts Consortium on Pathogen Readiness, Boston, MA 02115, USA; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA 02115, USA.

Publikováno v: Med (New York, N.Y.) [Med] 2022 Dec 09; Vol. 3 (12), pp. 883-900.e13. Date of Electronic Publication: 2022 Sep 19.