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pro vyhledávání: '"Baban Rupaji Thube"'
Autor:
Sagar J. Desai, Sameer S. Walunj, Anand M. Bokare, Sharad Sharma, Dhananjay Bakhle, Sachchidanand Sachchidanand, Mahip K. Verma, Rajesh Gupta, Vijaya Mahimane, Jayasagar Gundu, Baban Rupaji Thube, Prashant B. Nigade, Firoj Aftab Raje, Chirag Shah, Sanjay Pralhad Kurhade, M. K. Singh, Lairikyengbam Bikramjit Singh, Girish Dhanraj Hatnapure, Shridhar Keshav Adurkar, Rajender Kumar Kamboj, Vinod Patil, Neelima Sinha, Ajay Ramchandra Tilekar, Sudhakar Maruti Balgude, Sarita Koul, Manavi Chatterjee, Anil Kashiram Hajare, Ruchi Dixit, Yogesh Bhosale, Ganesh Rajaram Jadhav, Manoj P. Dandekar, Navnath Popat Karche, Dnyaneshwar Changdeo Bhanage, Ashish P. Bharne, Rajan Goel, Javed S Shaikh, Gourhari Jana, Dipak Modi, Maneesh Mehta, Venkata P. Palle
Publikováno v:
Journal of Medicinal Chemistry. 63:944-960
The discovery of a series of thiophenephenylsulfonamides as positive allosteric modulators (PAM) of α7 nicotinic acetylcholine receptor (α7 nAChR) is described. Optimization of this series led to identification of compound 28, a novel PAM of α7 ni