Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Babak, Behnam Azad"'
Autor:
Jacob Ziontz, Murat Bilgel, Andrea T. Shafer, Abhay Moghekar, Wendy Elkins, Jessica Helphrey, Gabriela Gomez, Danielle June, Michael A. McDonald, Robert F. Dannals, Babak Behnam Azad, Luigi Ferrucci, Dean F. Wong, Susan M. Resnick
Publikováno v:
Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, Vol 11, Iss 1, Pp 637-645 (2019)
Abstract Introduction Tau pathology, a hallmark of Alzheimer's disease, is observed in the brains of virtually all individuals over 70 years. Methods Using 18F‐AV‐1451 (18F‐flortaucipir) positron emission tomography, we evaluated tau pathology
Externí odkaz:
https://doaj.org/article/c72b594430654196b0394bb5b1f54f3f
Autor:
Qi Cao, Xin Lu, Babak Behnam Azad, Martin Pomper, Mark Smith, Jiang He, Liya Pi, Bin Ren, Zhekang Ying, Babak Saboury Sichani, Michael Morris, Vasken Dilsizian
Publikováno v:
Frontiers in Molecular Biosciences, Vol 7 (2020)
Introduction: Early-stage liver fibrosis is potentially reversible, but difficult to diagnose. Clinical management would be enhanced by the development of a non-invasive imaging technique able to identify hepatic injury early, before end-stage fibros
Externí odkaz:
https://doaj.org/article/11342a4d3d194230a1d41b37af4fe9cf
Publikováno v:
Pharmaceutics, Vol 14, Iss 3, p 655 (2022)
The chemokine receptor 4 (CXCR4) is a promising diagnostic and therapeutic target for the management of various cancers. CXCR4 has been utilized in immunotherapy, targeted drug delivery, and endoradiotherapy. Poly(amidoamine) [PAMAM] dendrimers are w
Externí odkaz:
https://doaj.org/article/c88fa19af1c74d70b16a2e72e447c6c9
Autor:
Babak Behnam Azad, Vanessa Rota, Lihai Yu, Rebecca Mcgirr, André H. St. Amant, Ting-Yim Lee, Savita Dhanvantari, Leonard G. Luyt PhD
Publikováno v:
Molecular Imaging, Vol 14 (2015)
A fluorescein-GLP-1 (7-37) analog was generated to determine GLP-1R distribution in various cell types of the pancreas in both strains of mice and receptor-specific uptake was confirmed by blocking with exendin-4. Biodistribution studies were carried
Externí odkaz:
https://doaj.org/article/5f3b5e72033541fca3b13a2fb36b1292
Autor:
Robert F. Dannals, Martin G. Pomper, Wojciech G. Lesniak, Ala Lisok, Yu Yan, Mary Brummet, Vanessa F. Merino, Babak Behnam Azad, Athira Narayan
Publikováno v:
Oncotarget
Neuroendocrine tumors (NETs) are an extremely heterogenous group of malignancies with variable clinical behavior. Molecular imaging of patients with NETs allows for effective patient stratification and treatment guidance and is crucial in selection o
Autor:
Jennifer M. Coughlin, Gwenn S. Smith, Allen R. Chen, Marilyn S. Albert, Laura K. Shinehouse, Erica S. Marshall, Robert F. Dannals, Sarah Frey, Dean F. Wong, Arnold Bakker, Yong Du, Wojciech G. Lesniak, Vidyulata Kamath, Caroline L. Speck, Babak Behnam Azad, Andrew G. Horti, Il Minn, Martin G. Pomper, Leah H. Rubin, Hailey B. Rosenthal, Yuchuan Wang, Jeffrey L. Crawford, Steven P. Rowe
Publikováno v:
Journal of Nuclear Medicine. 61:423-426
Emerging evidence supports a hypothesized role for the α7-nicotinic acetylcholine receptor (α7-nAChR) in the pathophysiology of Alzheimer's disease. 18F-ASEM (3-(1,4-diazabicyclo[3.2.2]nonan-4-yl)-6-18F-fluorodibenzo[b,d]thiophene 5,5-dioxide) is a
Autor:
Martin G. Pomper, Jan Gettemans, Miroslaw Janowski, Olivier Zwaenepoel, Wojciech G. Lesniak, Ala Lisok, Michał Zawadzki, Piotr Walczak, Babak Behnam Azad, Chengyan Chu, Anna Jablonska
Publikováno v:
Eur J Nucl Med Mol Imaging
INTRODUCTION: We have recently shown that intracerebral delivery of an anti-VEGF monoclonal antibody bevacizumab using an intra-arterial (IA) infusion is more effective than intravenous administration. While antibodies are quickly emerging as therape
Autor:
Martin G. Pomper, Sridhar Nimmagadda, Sangeeta Ray Banerjee, Srikanth Boinapally, Ala Lisok, Wojciech G. Lesniak, Catherine A. Foss, Chentian Shen, Bryan Wharram, Babak Behnam Azad
Publikováno v:
Molecular Pharmaceutics. 16:2590-2604
The prostate-specific membrane antigen (PSMA) is a validated target for detection and management of prostate cancer (PC). It has also been utilized for targeted drug delivery through antibody-drug conjugates and polymeric micelles. Polyamidoamine (PA
Autor:
Hong Fan, Jennifer M. Coughlin, Yong Du, Mary Katherine Brosnan, Steven P. Rowe, Wojciech G. Lesniak, Laura K. Shinehouse, Il Minn, Robert F. Dannals, Martin G. Pomper, Stephanie Slania, Babak Behnam Azad, Andrew G. Horti, Daniel P. Holt
Publikováno v:
Eur J Nucl Med Mol Imaging
Soluble epoxide hydrolase (sEH) is an enzyme with putative effect on neuroinflammation through its influence on the homeostasis of polyunsaturated fatty acids and related biproducts. Since sEH is an enzyme that metabolizes the anti-inflammatory epoxy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45fe1fdf4ca87eadab2dd23de679ead6
https://europepmc.org/articles/PMC10129439/
https://europepmc.org/articles/PMC10129439/
Autor:
Jiefu Jin, Desmond Jacob, Chentian Shen, Mir Shanaz Hossain, Babak Behnam Azad, Ala Lisok, Ying Chen, Ethel J. Ngen, Srikanth Boinapally, Zaver M. Bhujwalla, Sangeeta Ray Banerjee, Martin G. Pomper
Publikováno v:
Nanotheranostics
Enhanced vascular permeability in tumors plays an essential role in nanoparticle delivery. Prostate-specific membrane antigen (PSMA) is overexpressed on the epithelium of aggressive prostate cancers (PCs). Here, we evaluated the feasibility of increa