Long-Term Outcome in a Phase II Study of Regional Hyperthermia Added to Preoperative Radiochemotherapy in Locally Advanced and Recurrent Rectal Adenocarcinomas

Autor: Baard-Christian Schem, Frank Pfeffer, Martin Anton Ott, Johan N. Wiig, Nils Sletteskog, Torbjørn Frøystein, Mette Pernille Myklebust, Sabine Leh, Olav Dahl, Olav Mella

Publikováno v: Cancers, Vol 14, Iss 705, p 705 (2022)
Cancers; Volume 14; Issue 3; Pages: 705
Cancers

Hyperthermia was added to standard preoperative chemoradiation for rectal adenocarcinomas in a phase II study. Patients with T3-4 N0-2 M0 rectal cancer or local recurrences were included. Radiation dose was 54 Gy combined with capecitabine 825 mg/m2

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af6368b2b79a41f8db1231df8904f2e4
https://doi.org/10.3390/cancers14030705

First results of triple-modality treatment combining radiotherapy, chemotherapy, and hyperthermia for the treatment of patients with Stage IIB, III, and IVA cervical carcinoma

Autor: Peter Koper, Anneke M. Westermann, Elzbieta M. van der Steen-Banasik, Leonard R. Prosnitz, Baard-Christian Schem, Apollonia L. J. Uitterhoeve, Jacoba van der Zee, Clasina L. van der Wilt, Olav Dahl, Curt W. Burger, Jacobus van der Velden, Ellen L. Jones, Ronald de Wit, Olav Mella

Publikováno v: Cancer, 104(4), 763-770. John Wiley & Sons Inc.
Westermann, A M, Jones, E L, Schem, B C, van der Steen-Banasik, E M, Koper, P, Mella, O, Uitterhoeve, A L, de Wit, R, van, DV, Burger, C, van der Wilt, C L & Dahl, O 2005, ' First results of triple-modality treatment combining radiotherapy, chemotherapy, and hyperthermia for the treatment of patients with stage IIB, III, and IVA cervical carcinoma ', Cancer, vol. 104, no. 4, pp. 763-770 . https://doi.org/10.1002/cncr.21128
Cancer, 104(4), 763-770. John Wiley and Sons Inc.

BACKGROUND. Patients with advanced cervical carcinoma are treated routinely with radiotherapy and cisplatin-containing chemotherapy. It has been shown that hyperthermia can improve the results of both radiotherapy and cisplatin. In the current study,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f409f852b17d6a6fdaff77aa8d565dc8
https://doi.org/10.1002/cncr.21128

Timing of hypertonic glucose and thermochemotherapy with 1-(4-amino-2-methylpyrimidine-5-yl)methyl-3-(2-chloroethyl)-3-nitrosourea (acnu) in the BT4An rat glioma: Relation to intratumoral pH reduction and circulatory changes after glucose supply

Autor: Baard-Christian Schem, Bård Kronen Krossnes, Stefan Roszinski, Olav Mella

Publikováno v: International Journal of Radiation Oncology*Biology*Physics. 33:409-416

Purpose: Intraperitoneal hypertonic glucose has previously been shown to induce hyperglycemia, hemoconcentration, and to influence systemic and tumor circulation, and, thus, enhance the effect of thermochemotherapy with 1-(4-amino-2-methylpyrimidine-

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84f3ab11a9bb741d3d9fce50fffd33b8
https://doi.org/10.1016/0360-3016(95)00167-w

Thermochemotherapy with cisplatin or carboplatin in the BT4 rat glioma in vitro and in vivo

Autor: Olav Mella, Baard-Christian Schem, Olav Dahl

Publikováno v: International Journal of Radiation Oncology*Biology*Physics. 23:109-114

The effect of thermochemotherapy with cisplatin or carboplatin was compared in the BT 4 -cell line. In vitro . BT 4 C-cells were treated with different concentrations of cisplatin or carboplatin, with or without simultaneous hyperthermia. In vivo : I

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42daab97b811db77330321ec0ce5d52c
https://doi.org/10.1016/0360-3016(92)90549-w

cDNA microarray analysis of serially sampled cervical cancer specimens from patients treated with thermochemoradiotherapy

Autor: Baard-Christian Schem, Erling Dahl Borkamo, Olav Mella, Øystein Fluge, Ove Bruland, Olav Dahl

Publikováno v: International journal of radiation oncology, biology, physics. 75(5)

Purpose To elucidate changes in gene expression after treatment with regional thermochemoradiotherapy in locally advanced squamous cell cervical cancer. Methods and Materials Tru-Cut biopsy specimens were serially collected from 16 patients. Microarr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09337e7a5ad5abf4602d1783832a85b4
https://pubmed.ncbi.nlm.nih.gov/19931738