Zobrazeno 1 - 10
of 36
pro vyhledávání: '"BW-723C86"'
Autor:
Hiroaki Nishimura, Yoshio Kase, Kazushige Mizoguchi, Yasushi Ikarashi, Hirotaka Kushida, Yasushi Igarashi, Hitomi Kanno
Publikováno v:
Journal of Ethnopharmacology. 158:264-270
Ethnopharmacological relevance Geissoschizine methyl ether (GM) is an indole alkaloid that is a component of Uncaria Hook, and has been identified as the active component responsible for the anti-aggressive effects of the Uncaria Hook-containing trad
Autor:
James C. Matthews, James L. Klotz, James A. Boling, W. R. Burris, Y. Xue, Lowell P. Bush, J. R. Strickland, K. R. Brown
Publikováno v:
Journal of Animal Science. 90:682-693
As part of a 2-yr study documenting the physiologic impact of grazing endophyte-infected tall fescue on growing cattle, 2 experiments were conducted to characterize and evaluate effects of grazing 2 levels of toxic endophyte-infected tall fescue past
Publikováno v:
Behavioural Brain Research. 177:214-226
Animal models of anxiety remain a useful tool for evaluating the anxiolytic-like effect of new treatments. Even though many tests are similarly based on exploration tasks, using more than one animal model is all the more recommended since there are q
Publikováno v:
Pharmacological Research. 53:353-358
The 5-HT 4 receptor agonist and gastroprokinetic, tegaserod, possesses 5-HT 2B receptor antagonist activity. However, the relevance of such activity is unclear. In this study, the 5-HT 2B receptor antagonist and 5-HT 4 agonist activities of tegaserod
Publikováno v:
Hormone and Metabolic Research. 35:511-516
Effects of imipramine on plasma glucose levels were investigated in mice. Imipramine i.p. induced dose-dependent hyperglycemia, which was enhanced by pretreatment with 5-HT 1 / 2 / 5 / 7 receptor antagonist methysergide and 5-HT 2 A / 2 B / 2 C recep
Publikováno v:
Behavioural Brain Research. 140:203-214
The behavioural effects of 5-HT(2) receptor agonists, 5-HT(2A) and 5-HT(2C) receptor antagonists were investigated in the mouse four plates test (FPT), light/dark paradigm (L/D) and the elevated plus maze (EPM), in order to elucidate the role of the
Publikováno v:
Behavioral Neuroscience. 117:212-221
The role of serotonin 5-HT 2 receptors (5-HT 2 R) in the discriminative stimulus effects of fenfluramine was investigated. Male Sprague-Dawley rats were trained to discriminate (±)-fenfluramine (2 mg/kg ip) from saline using a 2-lever, water-reinfor
Publikováno v:
Pharmacology Biochemistry and Behavior. 71:709-716
The feeding effects of 5-hydroxytryptamine (5-HT)(1) and 5-HT(2) receptor agonists injected into the hypothalamic paraventricular nucleus (PVN) immediately prior to PVN administration of neuropeptide Y (NPY) were examined. The impact of these same co
Autor:
Guy A. Kennett, C.S. Malcolm, N.H Allen, N. Easton, Porter Richard Hugh Phillip, Steven P. Vickers, M.J Bickerdike
Publikováno v:
Pharmacology Biochemistry and Behavior. 69:643-652
The pharmacology of several commonly described 5-hydroxytryptamine (5-HT)(2C) receptor agonists was investigated in vivo and in vitro at rat 5-HT(2A), 5-HT(2B), and 5-HT(2C) receptors. The 5-HT(2C) receptor agonist, (S)-2-(6-chloro-5-fluoroindol-1-yl
Publikováno v:
Pharmacology Biochemistry and Behavior. 66:797-802
Although 5-HT(1/2) receptor agonists can inhibit ingestive behavior, it remains unclear whether this effect is confounded by drug-induced "malaise." The present study assessed the potential of such compounds to induce conditioned taste aversion (CTA)