Výsledky vyhledávání - "BV2 microglial cells"

Akademický článek

Temporal genome-wide fitness analysis of Mycobacterium marinum during infection reveals the genetic requirement for virulence and survival in amoebae and microglial cells

Autor: Louise H. Lefrançois, Jahn Nitschke, Huihai Wu, Gaël Panis, Julien Prados, Rachel E. Butler, Tom A. Mendum, Nabil Hanna, Graham R. Stewart, Thierry Soldati

Publikováno v: mSystems, Vol 9, Iss 2 (2024)

ABSTRACTTuberculosis remains the most pervasive infectious disease and the recent emergence of drug-resistant strains emphasizes the need for more efficient drug treatments. A key feature of pathogenesis, conserved between the human pathogen Mycobact

Externí odkaz: https://doaj.org/article/6f8ef12fa85142f6917fe6f2d44a0b6b

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The ethanolic extract of Curcuma longa grown in Korea exhibits anti-neuroinflammatory effects by activating of nuclear transcription factor erythroid-2-related factor 2/heme oxygenase-1 signaling pathway

Autor: Kwan-Woo Kim, Young-Seob Lee, Dahye Yoon, Geum-Soog Kim, Dae Young Lee

Publikováno v: BMC Complementary Medicine and Therapies, Vol 22, Iss 1, Pp 1-11 (2022)

Abstract Background Curcuma longa has been used as spices, food preservative, coloring material, and traditional medicine. This plant also has long been used for a variety of diseases including dyslipidemia, stomach disorders, arthritis, and hepatic

Externí odkaz: https://doaj.org/article/5711971e9e6f45359b415682a444c48f

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Senkyunolide H inhibits activation of microglia and attenuates lipopolysaccharide‐mediated neuroinflammation and oxidative stress in BV2 microglia cells via regulating ERK and NF‐κB pathway

Autor: Jun Tan, Wei Li, Zhipeng Teng, Guang Wang, Yanyan Li, Yuan Zhang

Publikováno v: Kaohsiung Journal of Medical Sciences, Vol 38, Iss 4, Pp 378-384 (2022)

Abstract Neuropathic pain is one of the common surgical diseases, which leads to abnormal chronic pain and pain hypersensitivity reaction. Microglia are important glial cells in the spinal cord, which are conducive to sensitization and maintenance of

Externí odkaz: https://doaj.org/article/59a2620b55694ba7895afb9b455eb091

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The therapeutic mechanism of Shenyuan Gan in lipopolysaccharide-induced neuroinflammation in BV2 microglial cells

Autor: Peng Sha, Peng Zhuang, Hu Qin, Liu Xinmin, Chen Ying, Shi Zhe

Publikováno v: Digital Chinese Medicine, Vol 5, Iss 1, Pp 75-82 (2022)

Objective: To study the therapeutic effects of Shenyuan Gan (参远苷, SYG) on the inflammatory response in BV2 microglial cells induced by lipopolysaccharide (LPS). Methods: The cytotoxicity of SYG to BV2 microglial cells was evaluated using a Cell

Externí odkaz: https://doaj.org/article/83c7a987cb7f4e3581943d4448db85f7

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Akademický článek

Pien Tze Huang Attenuates Neuro-inflammatory Injury in BV2 Microglial Cells Induced by Lipopolysaccharide via Inhibition of TLR4/MAPK Signaling Pathway

Autor: Zhenwei HUANG, Qing ZHANG, Lili HUANG, Xiaoqin ZHANG, Mingqing HUANG

Publikováno v: 康复学报, Vol 31, Pp 44-51 (2021)

Objective:To investigate the protective effect and the molecular mechanism of Pien Tze Huang (PZH) on Lipopolysaccharide (LPS) -induced neuro-inflammatory injury in BV2 microglial cells.Methods:BV2 microglial cells were cultured with RPMI-1640 medium

Externí odkaz: https://doaj.org/article/2a0d0f502e5f4ffe92a0e65e4edace4e

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Phyllanthus amarus prevents LPS-mediated BV2 microglial activation via MyD88 and NF-κB signaling pathways

Autor: Elysha Nur Ismail, Ibrahim Jantan, Sharmili Vidyadaran, Jamia Azdina Jamal, Norazrina Azmi

Publikováno v: BMC Complementary Medicine and Therapies, Vol 20, Iss 1, Pp 1-13 (2020)

Abstract Background Phyllanthus amarus has been shown to attenuate lipopolysaccharide (LPS)-induced peripheral inflammation but similar studies in the central nervous system are scarce. The aim of the present study was to investigate the neuroprotect

Externí odkaz: https://doaj.org/article/06124897944948a8bfb92155498e1355

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Attenuation of lipopolysaccharide-induced neuroinflammatory events in BV-2 microglial cells by Moringa oleifera leaf extract

Autor: Gothai Sivaprakasam, Palanivel Ganesan, Katyakyini Muniandy, Shin-Young Park, Duk-Yeon Cho, Joon-So Kim, Palanisamy Arulselvan, Dong-Kug Choi

Publikováno v: Asian Pacific Journal of Tropical Biomedicine, Vol 9, Iss 3, Pp 109-115 (2019)

Objective: To determine the anti-neuroinflammatory activity of Moringa oleifera leaf extract (MLE) under lipopolysaccharide stimulation of mouse murine microglia BV2 cells in vitro. Methods: The cytotoxicity effect of MLE was investigated by 3-(4, 5-

Externí odkaz: https://doaj.org/article/48444daf58cb4208814ee82d328cce56

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