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Akademický článek

Evaluation of inflammatory biomarkers and their association with anti-SARS-CoV-2 antibody titers in healthcare workers vaccinated with BNT162B2

Autor: Ester Leno-Duran, Esther Serrano-Conde, Ana Salas-Rodríguez, Inmaculada Salcedo-Bellido, Rocío Barrios-Rodríguez, Ana Fuentes, Laura Viñuela, Federico García, Pilar Requena

Publikováno v: Frontiers in Immunology, Vol 15 (2024)

IntroductionVaccine-induced immunity against COVID-19 generates antibody and lymphocyte responses. However, variability in antibody titers has been observed after vaccination, and the determinants of a better response should be studied. The main obje

Externí odkaz: https://doaj.org/article/07f4d21c666342e0bfbafb3233a55cb7

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Akademický článek

Subjects who developed SARS-CoV-2 specific IgM after vaccination show a longer humoral immunity and a lower frequency of infectionResearch in context

Autor: Chiara Piubelli, Alessandra Ruggiero, Lucia Calciano, Cristina Mazzi, Concetta Castilletti, Natalia Tiberti, Sara Caldrer, Matteo Verzè, Silvia Stefania Longoni, Simone Accordini, Zeno Bisoffi, Donato Zipeto

Publikováno v: EBioMedicine, Vol 89, Iss , Pp 104471- (2023)

Summary: Background: We have previously shown that eliciting SARS-CoV-2-specific IgM after vaccination is associated with higher levels of SARS-CoV-2 neutralizing IgG. This study aims to assess whether IgM development is also associated with longer-l

Externí odkaz: https://doaj.org/article/20dd6570f69c41c09e2daf5600a477d6

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Akademický článek

Different decay of antibody response and VOC sensitivity in naïve and previously infected subjects at 15 weeks following vaccination with BNT162b2

Autor: Gabriel Siracusano, Alessandra Ruggiero, Zeno Bisoffi, Chiara Piubelli, Luca Dalle Carbonare, Maria Teresa Valenti, Martin Mayora-Neto, Nigel Temperton, Lucia Lopalco, Donato Zipeto

Publikováno v: Journal of Translational Medicine, Vol 20, Iss 1, Pp 1-7 (2022)

Abstract Background COVID-19 vaccines have demonstrated effectiveness in reducing SARS-CoV-2 mild and severe outcomes. In vaccinated subjects with SARS-CoV-2 history, RBD-specific IgG and pseudovirus neutralization titers were rapidly recalled by a s

Externí odkaz: https://doaj.org/article/95f110a798a94c73986a87772d2705f5

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Akademický článek

Real-world vaccine effectiveness of mRNA vaccines for SARS-CoV-2; a test-negative case-control study in a medium-sized clinic

Autor: Masahiro Aoshima, Satoko Ohfuji

Publikováno v: Human Vaccines & Immunotherapeutics, Vol 18, Iss 7 (2022)

Although nationwide immunization with SARS-CoV-2 mRNA vaccines began in February 2021, the evaluation of vaccine effectiveness (VE) using a test-negative design has not been conducted adequately in Japan. To evaluate the effectiveness of the SARS-CoV

Externí odkaz: https://doaj.org/article/ba172bc115eb46e597eaf08b1c3b73a1

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Akademický článek

SARS-CoV-2 vaccination elicits unconventional IgM specific responses in naïve and previously COVID-19-infected individuals

Autor: Alessandra Ruggiero, Chiara Piubelli, Lucia Calciano, Simone Accordini, Maria Teresa Valenti, Luca Dalle Carbonare, Gabriel Siracusano, Nigel Temperton, Natalia Tiberti, Silvia Stefania Longoni, Massimo Pizzato, Silvia Accordini, Tobia Fantoni, Lucia Lopalco, Alberto Beretta, Zeno Bisoffi, Donato Zipeto

Publikováno v: EBioMedicine, Vol 77, Iss , Pp 103888- (2022)

Summary: Background: Currently, evaluation of the IgG antibodies specific for the SARS-CoV-2 Spike protein following vaccination is used worldwide to estimate vaccine response. Limited data are available on vaccine-elicited IgM antibodies and their p

Externí odkaz: https://doaj.org/article/828ced340f2d48138a9e0f56b8055c59

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Akademický článek

Specific T-Cell Immune Response to SARS-CoV-2 Spike Protein over Time in Naïve and SARS-CoV-2 Previously Infected Subjects Vaccinated with BTN162b2

Autor: Natali Vega-Magaña, José Francisco Muñoz-Valle, Marcela Peña-Rodríguez, Oliver Viera-Segura, Ana Laura Pereira-Suárez, Jorge Hernández-Bello, Mariel García-Chagollan

Publikováno v: Vaccines, Vol 10, Iss 7, p 1117 (2022)

Due to the COVID-19 pandemic, the rapid development of vaccines against SARS-CoV-2 has been promoted. BNT162b2 is a lipid-nanoparticle mRNA vaccine with 95% efficacy and is the most administered vaccine globally. Nevertheless, little is known about t

Externí odkaz: https://doaj.org/article/ecc3dc7d4a78471f857e3593e4aedf55

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