Zobrazeno 1 - 10
of 738
pro vyhledávání: '"BTK INHIBITOR"'
Publikováno v:
Experimental Hematology & Oncology, Vol 13, Iss 1, Pp 1-11 (2024)
Abstract Follicular lymphoma (FL) is an indolent, germinal center B cell–derived lymphoid neoplasm, for which recent advances in treatment have substantially improved patient survival. However, FL remains an incurable and heterogeneous disease, wit
Externí odkaz:
https://doaj.org/article/85a2892529414ce1aa105915033a0f01
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
Dermatological adverse events (AEs) are generally mild during therapy with Bruton’s tyrosine kinase inhibitor (BTKi), and it is often unnecessary to adjust the BTKi dosage or discontinue treatment. However, in this study, we present the cases of tw
Externí odkaz:
https://doaj.org/article/7d94ee6f3c2c4279b315ecd95a33e82f
Autor:
Alexander Englisch, Clara Hayn, Susanne Jung, Jonas S. Heitmann, Christopher Hackenbruch, Yacine Maringer, Annika Nelde, Marcel Wacker, Monika Denk, Lisa Zieschang, Christine Kammer, Peter Martus, Helmut R. Salih, Juliane S. Walz
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
Chronic lymphocytic leukemia (CLL) is the most common form of leukemia among adults in Western countries. Despite the introduction of targeted therapies, including first-line Bruton’s tyrosine kinase inhibitor (BTKi) treatment, CLL remains largely
Externí odkaz:
https://doaj.org/article/dd7432dd452f4e3c895e7e3e1fbf5b55
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 11 (2024)
Externí odkaz:
https://doaj.org/article/030e116712aa4a96ba9ee9c5b6ade6fe
Publikováno v:
Medicine in Novel Technology and Devices, Vol 22, Iss , Pp 100295- (2024)
Exploring novel therapeutic targets of Diffuse large B cell lymphoma (DLBCL) to overcome its resistance to Bruton's Tyrosine Kinase (BTK) inhibitors is a key topic. Lipid metabolism, crucial in the resistance landscape of various cancers, may unlock
Externí odkaz:
https://doaj.org/article/0491323f5c874a1c8334b630333f19b2
Autor:
Issei Nakade, Yuto Tamura, Fuyu Hashimoto, Yuko Ariza, Shingo Hotta, Hirofumi Fujigaya, Suishin Arai, Mai Taniguchi, Hodaka Ogawa, Yuka Nishibata, Sakiko Masuda, Daigo Nakazawa, Utano Tomaru, Akihiro Ishizu
Publikováno v:
Arthritis Research & Therapy, Vol 25, Iss 1, Pp 1-12 (2023)
Abstract Background Bruton’s tyrosine kinase (Btk) is an enzyme expressed in leukocytes other than T lymphocytes and plasma cells and involved in B-cell receptor- and Fcγ receptor (FcγR)-mediated signal transduction. Btk inhibitors potentially su
Externí odkaz:
https://doaj.org/article/060a526975d94c7b99f7ab3eb6855475
Autor:
Neeraj Jain, Mukesh Mamgain, Sayan Mullick Chowdhury, Udita Jindal, Isha Sharma, Lalit Sehgal, Narendranath Epperla
Publikováno v:
Journal of Hematology & Oncology, Vol 16, Iss 1, Pp 1-26 (2023)
Abstract Mantle cell lymphoma is a B cell non-Hodgkin lymphoma (NHL), representing 2–6% of all NHLs and characterized by overexpression of cyclin D1. The last decade has seen the development of many novel treatment approaches in MCL, most notably t
Externí odkaz:
https://doaj.org/article/b1e55395cfef45b29bb14f52778076da
Publikováno v:
Journal of Hematology & Oncology, Vol 16, Iss 1, Pp 1-22 (2023)
Abstract Background The treatment landscape for chronic lymphocytic leukemia (CLL) continues to undergo considerable evolution. Optimal selection of initial therapy from multiple effective options provides a major challenge for clinicians, who need t
Externí odkaz:
https://doaj.org/article/9d84a95dd0164a698d00f4f306151f3d
Autor:
Karan L. Chohan, Prashant Kapoor
Publikováno v:
Hemato, Vol 4, Iss 2, Pp 135-157 (2023)
Waldenström macroglobulinemia (WM) is a rare, non-Hodgkin lymphoma that remains incurable. Rituximab, an anti-CD20 monoclonal antibody has been the cornerstone of treatment against WM, and its combination with an alkylator, bendamustine, achieves du
Externí odkaz:
https://doaj.org/article/6928ef044f5c4db09847ed4b659b1d83
Autor:
Malarz K, Korzuch J, Marforio TD, Balin K, Calvaresi M, Mrozek-Wilczkiewicz A, Musiol R, Serda M
Publikováno v:
International Journal of Nanomedicine, Vol Volume 18, Pp 1709-1724 (2023)
Katarzyna Malarz,1,* Julia Korzuch,2,* Tainah Dorina Marforio,3 Katarzyna Balin,1 Matteo Calvaresi,3 Anna Mrozek-Wilczkiewicz,1 Robert Musiol,2 Maciej Serda2 1A. Chełkowski Institute of Physics, University of Silesia in Katowice, Chorz
Externí odkaz:
https://doaj.org/article/a6aa4958fd384c649754429eb7a3c3a5