Zobrazeno 1 - 10
of 2 299
pro vyhledávání: '"BRUCE D. HAMMOCK"'
Autor:
Rice, Marlin E (AUTHOR)
Publikováno v:
American Entomologist. Spring2020, Vol. 66 Issue 1, p14-19. 6p.
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-20 (2024)
Abstract Oxylipins are a group of bioactive fatty acid metabolites generated via enzymatic oxygenation. They are notably involved in inflammation, pain, vascular tone, hemostasis, thrombosis, immunity, and coagulation. Oxylipins have become the focus
Externí odkaz:
https://doaj.org/article/c5206c6a1782433c8a8dc0ac63a80288
Autor:
William K. Schmidt, Irene Cortés‐Puch, Cindy B. McReynolds, Glenn E. Croston, Sung Hee Hwang, Jun Yang, Theresa L. Pedersen, Karen M. Wagner, Theresa T. Pham, Thomas Hunt, Bruce D. Hammock
Publikováno v:
Clinical and Translational Science, Vol 17, Iss 9, Pp n/a-n/a (2024)
Abstract Chronic pain represents a significant unmet medical need, affecting one‐fifth of the U.S. population. EC5026 is a small molecule inhibitor of the enzyme soluble epoxide hydrolase (sEH) which is being developed as a novel non‐opioid, non
Externí odkaz:
https://doaj.org/article/d23ba464802241f69df3a0fdd283dc0d
Autor:
Tayleur D. White, Abdulaziz Almutairi, Ying Gai-Tusing, Daniel J. Stephenson, Benjamin D. Stephenson, Charles E. Chalfant, Xiaoyong Lei, Brian Lu, Bruce D. Hammock, Teresa P. DiLorenzo, Sasanka Ramanadham
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionWe reported that Ca2+-independent phospholipase A2β (iPLA2β)–derived lipids (iDLs) contribute to type 1 diabetes (T1D) onset. As CD4+ and CD8+ T cells are critical in promoting β-cell death, we tested the hypothesis that iDL signalin
Externí odkaz:
https://doaj.org/article/588f970bbb8d45fbb26e60d608d19390
Autor:
Marlin E. Rice
Publikováno v:
American Entomologist. 66:14-19
Autor:
Yun Gui, Yun Zhao, Pengyan Liu, Yulong Wang, Xinxin Mao, Chifang Peng, Bruce D. Hammock, Cunzheng Zhang
Publikováno v:
ACS Omega, Vol 9, Iss 6, Pp 7075-7084 (2024)
Externí odkaz:
https://doaj.org/article/03e2ca24e17d4e44920a773ac8551e53
Autor:
Jeannes Angelia, Leah Duong, Faye Yun, Anesa Mesic, Cassandra Yuan, Daniel Carr, Siena Gunari, Paula K. Hudson, Christophe Morisseau, Bruce D. Hammock, Ram Kandasamy, Stevan Pecic
Publikováno v:
Heliyon, Vol 10, Iss 11, Pp e32262- (2024)
Simultaneous inhibition of soluble epoxide hydrolase (sEH) and fatty acid amide hydrolase (FAAH) with a single small molecule represents a novel therapeutic approach in treating inflammatory pain, since both targets are involved in pain and inflammat
Externí odkaz:
https://doaj.org/article/a9debe63a822457898455455adf78d0e
Autor:
Denis Babkov, Natalya Eliseeva, Kristina Adzhienko, Viktoria Bagmetova, Dmitry Danilov, Cynthia B. McReynolds, Christophe Morisseau, Bruce D. Hammock, Vladimir Burmistrov
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 16, p 8841 (2024)
Inhibition of soluble epoxide hydrolase (sEH) is a promising therapeutic strategy for treating neuropathic pain. These inhibitors effectively reduce diabetic neuropathic pain and inflammation induced by Freund’s adjuvant which makes them a suitable
Externí odkaz:
https://doaj.org/article/063cf443125142fdb1fad3ed14a37aeb
Autor:
Zumer Naeem, Sven Zukunft, Arnaud Huard, Jiong Hu, Bruce D. Hammock, Andreas Weigert, Timo Frömel, Ingrid Fleming
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 171, Iss , Pp 116127- (2024)
The lipid content of skin plays a determinant role in its barrier function with a particularly important role attributed to linoleic acid and its derivatives. Here we explored the consequences of interfering with the soluble epoxide hydrolase (sEH) o
Externí odkaz:
https://doaj.org/article/007633b0f61941f286a9a83ad9234b49
Nanobody-based bispecific T-cell engager (Nb-BiTE): a new platform for enhanced T-cell immunotherapy
Autor:
Xiao-mei Yang, Xuan-dong Lin, Wei Shi, Shen-xia Xie, Xia-ning Huang, Shi-hua Yin, Xiao-bing Jiang, Bruce D. Hammock, Zhi Ping Xu, Xiao-ling Lu
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 8, Iss 1, Pp 1-4 (2023)
Externí odkaz:
https://doaj.org/article/d59055c881184cd391204872905dfa75