Zobrazeno 1 - 10
of 31
pro vyhledávání: '"BRUCE C. HAMPER"'
Autor:
Bruce C. Hamper, Joseph W. Meisel
Publikováno v:
Journal of Chemical Education. 97:1289-1294
“Beer Brewing: Chemical and Biochemical Principles” is a 15 week laboratory and lecture course specifically designed for nonscience majors as an introduction to science literacy via structured labo...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5cdf638d7243f6875397a072685ee579
https://doi.org/10.1021/acs.jchemed.9b00870
https://doi.org/10.1021/acs.jchemed.9b00870
Publikováno v:
Journal of the American Society of Brewing Chemists. 75:333-338
The chemical analysis of hop-derived humulone and isohumulone components in hops and beer was investigated using multiple injections in a single experimental run (MISER) extracted ion LC-MS. Compar...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::579dc320ec2d69d42b2b8a1d898008e1
https://doi.org/10.1094/asbcj-2017-4534-01
https://doi.org/10.1094/asbcj-2017-4534-01
Publikováno v:
Synthesis. 49:5335-5338
Acrylohydroxamic acid, which is a useful monomer for the preparation of polymeric materials, has been prepared in a straightforward, two-step synthesis from readily available starting materials. The key steps are coupling of acrylic acid with O-tetra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::203d72e742d607069e7ffb025cb4685d
https://doi.org/10.1055/s-0036-1589103
https://doi.org/10.1055/s-0036-1589103
Autor:
Michael P. Mannino, Bruce C. Hamper, Christopher D. Spilling, Liam T. Harrison, Melissa E. Mueller
Publikováno v:
Chirality. 28:656-662
Chromatographic separation of the enantiomers of parent compounds dimethyl α-hydroxyallyl phosphonate and 1-(dimethoxyphosphoryl) allyl methyl carbonate was demonstrated by high-performance liquid chromatography (HPLC) using Chiralpak AS-H and ad-H
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a48242ab41cb96eb0ed66658bbbf3d4c
https://doi.org/10.1002/chir.22627
https://doi.org/10.1002/chir.22627
Autor:
Michael David Rogers, Jeffery N. Carroll, Mark A. Massa, Jeffrey Hitchcock, Peter G. Ruminski, Michelle A. Schmidt, Bruce C. Hamper, Strohbach Joseph Walter, Huey S. Shieh, Laurence O. Whiteley, Katherine E. Palmquist, Joe T. Collins, Grace E. Munie, Hanau Cathleen E, H. Peter Kleine, Mark E. Schnute, T. Sunyer, Nicole Caspers, John E. Baldus, Theresa R. Fletcher, Joseph J. McDonald, Silvia Portolan, Jeffrey A. Scholten, Dean Messing, Margaret L. Grapperhaus, Brandon Collins
Publikováno v:
Journal of Medicinal Chemistry. 59:313-327
Matrix metalloproteinase-13 (MMP-13) is a zinc-dependent protease responsible for the cleavage of type II collagen, the major structural protein of articular cartilage. Degradation of this cartilage matrix leads to the development of osteoarthritis.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b1bf588f2b187240a5d8f4d5ee2e305b
https://doi.org/10.1021/acs.jmedchem.5b01434
https://doi.org/10.1021/acs.jmedchem.5b01434
Autor:
Sudeshna Roy, Nongnuch Sutivisedsak, Christopher D. Spilling, Bruce C. Hamper, Alexander M. Lyss
Publikováno v:
Synthesis. 47:3669-3672
The preparation of ( S )- and ( R )-1-(dimethoxyphosphoryl)allyl methyl carbonates is achieved on multigram scale from commercially available dimethyl phosphite and acrolein in three steps. The key steps involve an asymmetric Pudovik reaction and enz
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5736d25eecff7e51eec14156f741d779
https://doi.org/10.1055/s-0035-1560487
https://doi.org/10.1055/s-0035-1560487
Autor:
Bruce C, Hamper, Michael P, Mannino, Melissa E, Mueller, Liam T, Harrison, Christopher D, Spilling
Publikováno v:
Chirality. 28(9)
Chromatographic separation of the enantiomers of parent compounds dimethyl α-hydroxyallyl phosphonate and 1-(dimethoxyphosphoryl) allyl methyl carbonate was demonstrated by high-performance liquid chromatography (HPLC) using Chiralpak AS-H and ad-H
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::eeeec766c98a9d0019e53a3660841014
https://pubmed.ncbi.nlm.nih.gov/27516372
https://pubmed.ncbi.nlm.nih.gov/27516372
Autor:
James K. Gierse, Jeffery S. Carter, Li Xing, Bruce C. Hamper, Liao Subo, Jay M. Wendling, Theresa R. Fletcher
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 21:993-996
Combination of the structure-based design and solid-phase parallel synthesis provided an integrated approach to rapidly develop the structure-activity relationship of benzopyran COX-2 inhibitors. Binding free energies predicted by free energy perturb
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3d81c3439d005cb61361c5519f07153
https://doi.org/10.1016/j.bmcl.2010.12.023
https://doi.org/10.1016/j.bmcl.2010.12.023
Autor:
Ann E. Hallinan, Jeffery S. Carter, David G. Brown, John J. Talley, Timothy Maziasz, Karl W. Aston, Bruce C. Hamper, Matthew J. Graneto, Koszyk Francis, Jaime L. Masferrer, Ludwig Cindy L, Jane L. Wang, David C. Limburg
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 20:7164-7168
In this manuscript, we report the discovery of the substituted 2-trifluoromethyl-2H-benzopyran-3-carboxylic acids as a novel series of potent and selective cyclooxygenase-2 (COX-2) inhibitors. We provide the structure–activity relationships, optimi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca972ff580b09dc552a085ce8062ac97
https://doi.org/10.1016/j.bmcl.2010.07.059
https://doi.org/10.1016/j.bmcl.2010.07.059
Autor:
Barbara A. Schweitzer, Atli Thorarensen, Michael S. Davies, Steve R. Turner, Matthew James Pelc, James R. Kiefer, Brenda L. Case, Christie L. Funckes-Shippy, Jacqueline E. Day, Fengmei Hua, Dice Tom, William M. Abraham, Bradley E. Neal, John I. Trujillo, Joseph B. Moon, Blake Tanisha Danielle Rowe, Wei Huang, Craig D. Wegner, Dean Welsch, Chris P. Carron, Anup Zutshi, Bruce C. Hamper, Chad J. Warren, Rhonda S. Woerndle, Christine M. Kornmeier, Vickie M. Dilworth, Melanie L. Williams, Martin E. Dowty, Olson Kirk Lang, Melissa R. Radabaugh, Becky L. Hood, Jerry Z. Yang, Douglas C. Rohrer, Gina M. Jerome, Christine P. Bono
Publikováno v:
ACS Medicinal Chemistry Letters. 1:59-63
Hematopoietic prostaglandin D synthase (HPGDS) is primarly expressed in mast cells, antigen-presenting cells, and Th-2 cells. HPGDS converts PGH2 into PGD2, a mediator thought to play a pivotal role in airway allergy and inflammatory processes. In th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e6559b7ee90a239bc2255e65f4dd700
https://doi.org/10.1021/ml900025z
https://doi.org/10.1021/ml900025z