Zobrazeno 1 - 10
of 39
pro vyhledávání: '"BRIAN D. KELLEY"'
Publikováno v:
Biotechnology Progress. 37
Few monoclonal antibodies are currently approved for treating infectious diseases, but multiple products are in development against a broad range of infectious diseases, including Ebola, influenza, hepatitis B, HIV, dengue, and COVID-19. The maturity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1616c39fea8dfca2143433fdc2844eec
https://doi.org/10.1002/btpr.3139
https://doi.org/10.1002/btpr.3139
Autor:
Robert Puskeiler, Brian D. Kelley, Annika Kleinjans, Steven J. Meier, Rick St. John, Christian Hakemeyer, Fred Lim, Nathan McKnight, Melody Trexler-Schmidt, Christine Wurth, Frank Zettl
Publikováno v:
Biologicals. 44:306-318
Quality by design (QbD) is a global regulatory initiative with the goal of enhancing pharmaceutical development through the proactive design of pharmaceutical manufacturing process and controls to consistently deliver the intended performance of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c84ddf3148a241822ebcccedc5270a2c
https://doi.org/10.1016/j.biologicals.2016.06.004
https://doi.org/10.1016/j.biologicals.2016.06.004
Autor:
Christopher Williams, Ti Zhao, Benjamin Tran, Brian D. Kelley, Paul J. Mcdonald, Marc Wong, Philip Lester
Publikováno v:
Journal of Chromatography A. 1433:66-74
Cation-exchange chromatography is widely used in the purification of therapeutic antibodies, wherein parameters such as elution pH and counterion concentration require optimization for individual antibodies across different chromatography resins. Wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::873b215c3172319c84e9493cced24ed2
https://doi.org/10.1016/j.chroma.2015.12.071
https://doi.org/10.1016/j.chroma.2015.12.071
Autor:
John W. Armando, E. Morrey Atkinson, Peter Bernhardt, Torbjörn S. Blank, Yvonne A. Brady, Eggert Brekkan, Andrea Buchacher, Karolina Busson, Maire H. Caparon, Enrique N. Carredano, Jeffrey R. Carter, Andreas Castan, Shuang Chen, Kenneth P. Clapp, Scott A. Cook, John T. Cundy, John M. Curling, Åke Danielsson, Kjell O. Eriksson, Alain Fairbank, Suzanne S. Farid, Simon Fischer, Kine A.-K. Frej, Parrish M. Galliher, Klaus Gebauer, Glen S. Giese, Alan Gilbert, Anna Grönberg, Albrecht Gröner, Robert S. Gronke, Martin Hall, Kim R. Hejnaes, Rachel S. Hendricks, Rolf A. Hjorth, Geoff Hodge, Matt H. Hutchinson, Günter Jagschies, Michael J. Jenkins, Mikael I. Johansson, John Joseph, Oliver Kaltenbrunner, Gautam Kapoor, Tomas M. Karlsson, Brian D. Kelley, Annika Kleinjans, Jashwant Kumar, Karol M. Łącki, Philip Lester, Jakob Liderfelt, Xin Xin Lin, Eva K. Lindskog, Mats Lundgren, Ratish Mangalath-Illam, Trevor J. Marshall, Joseph P. Martin, Krunal K. Mehta, Brian Montgomery, Daniel Nelson, Roger Nordberg, Dana A. Olson, Martin Östling, John P. Pieracci, David J. Pollard, Alain Pralong, Hari Pujar, Joost P. Quaadgras, Tom C. Ransohoff, Anurag S. Rathore, Craig Robinson, Jonathan Royce, Michael A. Rubacha, Henrik Sandegren, Andreas Schaubmar, Patrick Schulz, Sumit K. Singh, Stephen E. Sobacke, Sriram Srinivasan, Matthew J. Stork, Bruce S. Tangarone, Jorg Thommes, Matthew J. Traylor, Johan Tschöp, James M. Van Alstine, Johnson Varghese, Ganesh Vedantham, Thomas von Hirschheydt, William B. Wellborn, Till Wenger, Susanne Westin, David G. Westman, Matthew Westoby, William G. Whitford, Ambrose J. Williams, John M. Woodgate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7ab37a02755962071e60b3fe89a67442
https://doi.org/10.1016/b978-0-08-100623-8.09990-4
https://doi.org/10.1016/b978-0-08-100623-8.09990-4
Therapeutic antibodies have been manufactured since the advent of intravenous immunoglobulin in the 1950s. Rituxan was the first recombinant monoclonal antibody approved for therapeutic use by the U.S. Food and Drug Administration (FDA) in 1997. Now,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::26ca106817d0797a51310a1fbc5e1829
https://doi.org/10.1016/b978-0-08-100623-8.00051-7
https://doi.org/10.1016/b978-0-08-100623-8.00051-7
Autor:
Brian D. Kelley
Publikováno v:
Biologicals : journal of the International Association of Biological Standardization. 44(5)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43590306660849f36fa9ffd4d6b2c8f0
https://pubmed.ncbi.nlm.nih.gov/27427518
https://pubmed.ncbi.nlm.nih.gov/27427518
Autor:
Lynne A. Krummen, Brian D. Kelley, Niklas Engler, Raquel Iverson, Gerald Gellermann, Ron Taticek, Christof Finkler, Reed J. Harris, Lynn A. Gennaro, Mary E.M. Cromwell, J. Felix Kepert, Nathan McKnight, Paul Motchnik, Volker Schnaible
Publikováno v:
Biologicals : journal of the International Association of Biological Standardization. 44(5)
Quality by design (QbD) is a global regulatory initiative with the goal of enhancing pharmaceutical development through the proactive design of pharmaceutical manufacturing process and controls to consistently deliver the intended performance of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b38b658a3d778fd4dbaad2ce6e6806f
https://pubmed.ncbi.nlm.nih.gov/27430904
https://pubmed.ncbi.nlm.nih.gov/27430904
Publikováno v:
Biologicals : journal of the International Association of Biological Standardization. 44(5)
Quality by design (QbD) is a global regulatory initiative with the goal of enhancing pharmaceutical development through the proactive design of pharmaceutical manufacturing process and controls to consistently deliver the intended performance of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::879a10952cca78fb4267189724053a12
https://pubmed.ncbi.nlm.nih.gov/27461127
https://pubmed.ncbi.nlm.nih.gov/27461127
Publikováno v:
Biotechnology Progress. 27:140-152
Formulation of protein biopharmaceuticals as highly concentrated liquids can improve the drug substance storage and supply chain, improve the target product profile, and allow greater flexibility in dosing methods. The Donnan effect can cause a large
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76cc803598dbfcf25b18bd770f2965f3
https://doi.org/10.1002/btpr.523
https://doi.org/10.1002/btpr.523