Zobrazeno 1 - 10
of 545
pro vyhledávání: '"BREIMER, D. D."'
Publikováno v:
Journal of pharmacology and experimental therapeutics, 279(3), 1439-1446. American Society for Pharmacology and Experimental Therapeutics
The cardiovascular effects of the nonselective adenosine receptor agonist 8-butylaminoadenosine (BAA) were quantified in conscious normotensive rats. The potency and intrinsic activity for the A1 and A2a receptor were determined separately. The rats
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=narcis______::8ca6946e4cfc652e05f94f2c01468768
https://pure.amc.nl/en/publications/partial-agonism-of-the-nonselective-adenosine-receptor-agonist-8butylaminoadenosine-at-the-a1-receptor-in-vivo(84f78da5-33d2-4264-95d1-091c5c17eaa8).html
https://pure.amc.nl/en/publications/partial-agonism-of-the-nonselective-adenosine-receptor-agonist-8butylaminoadenosine-at-the-a1-receptor-in-vivo(84f78da5-33d2-4264-95d1-091c5c17eaa8).html
Autor:
Mathôt, R. A., van den Aarsen, B. C., Soudijn, W., Breimer, D. D., IJzerman, A. P., Danhof, M.
Publikováno v:
Journal of pharmacology and experimental therapeutics, 273(1), 405-414. American Society for Pharmacology and Experimental Therapeutics
Recently, the commercially available adenosine receptor agonist S-N6-phenylisopropyladenosine (S-PIA) has been demonstrated to be contaminated with the more potent R-diastereomer. The potency of S-PIA may therefore have been overestimated in previous
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=narcis______::65c46e813f83eddda316e09ac84e0385
https://pure.amc.nl/en/publications/pharmacokineticpharmacodynamic-modelling-of-the-cardiovascular-effects-of-r-and-sn6phenylisopropyladenosine-in-conscious-normotensive-rats(447c2453-9605-40eb-bcd1-d57c3fcbb53b).html
https://pure.amc.nl/en/publications/pharmacokineticpharmacodynamic-modelling-of-the-cardiovascular-effects-of-r-and-sn6phenylisopropyladenosine-in-conscious-normotensive-rats(447c2453-9605-40eb-bcd1-d57c3fcbb53b).html
Autor:
Mathôt, R. A., van Schaick, E. A., Langemeijer, M. W., Soudijn, W., Breimer, D. D., IJzerman, A. P., Danhof, M.
Publikováno v:
Journal of pharmacology and experimental therapeutics, 268(2), 616-624. American Society for Pharmacology and Experimental Therapeutics
The purpose of the investigation was to develop a pharmacokinetic-pharmacodynamic model for the characterization of the cardiovascular effects of the adenosine A1 receptor agonist N6-cyclopentyladenosine (CPA) in individual normotensive rats. After t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=narcis______::5f7c25d3e0e5164e264ba90f1584665f
https://pure.amc.nl/en/publications/pharmacokineticpharmacodynamic-relationship-of-the-cardiovascular-effects-of-adenosine-a1-receptor-agonist-n6cyclopentyladenosine-in-the-rat(418d0f10-1f5b-4294-8e56-447bcec847e2).html
https://pure.amc.nl/en/publications/pharmacokineticpharmacodynamic-relationship-of-the-cardiovascular-effects-of-adenosine-a1-receptor-agonist-n6cyclopentyladenosine-in-the-rat(418d0f10-1f5b-4294-8e56-447bcec847e2).html
Autor:
De Boer, A G, Breimer, D D
The blood-brain barrier (BBB) determines whether or not a given drug can reach the central nervous system (CNS), either by passive diffusion or through carrier or receptor systems. Initial work focused on the structural and physico-chemical requireme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7491f893846f5b44b820de5e3ee46160
https://europepmc.org/articles/PMC5401103/
https://europepmc.org/articles/PMC5401103/
Publikováno v:
British Journal of Clinical Pharmacology, 35(5). Wiley-Blackwell
Van Steveninck, A L, Van Berckel, B N M, Schoemaker, H C, Breimer, D D & Cohen, A F 1993, ' Sensitivity of CNS performances tests to the effects of sleep deprivation ', British Journal of Clinical Pharmacology, vol. 35, no. 5 .
Van Steveninck, A L, Van Berckel, B N M, Schoemaker, H C, Breimer, D D & Cohen, A F 1993, ' Sensitivity of CNS performances tests to the effects of sleep deprivation ', British Journal of Clinical Pharmacology, vol. 35, no. 5 .
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::d6bdf42bb4d01e98bff284a5f15a735e
https://research.vumc.nl/en/publications/d0a73602-0230-495b-8d6b-f9872bd6850d
https://research.vumc.nl/en/publications/d0a73602-0230-495b-8d6b-f9872bd6850d
Autor:
van der Aa, G. C. H. M., Baeyens, J. P., Breimer, D. D., van der Cammen, T. J. M., Feuth, J. D. M., Jansen, P. A. F., Mulder, J. D., Ornée, J. M., Persijn, L. E., Spreeuwenberg, C., Ligthart, G. J.
Publikováno v:
Inleiding Gerontologie En Geriatrie; 2004, p55-84, 30p
Autor:
Rollema, H., Grol, C. J., Feenstra, M. G. P., van Oene, Joop C., Houwing, Hendrik A., Horn, Alan S., Ijzerman, A. P., Bultsma, T., Timmerman, H., Zaagsma, J., van der Graaff, M., Vermeulen, N. P. E., Joeres, R. P., Breimer, D. D., Tsantili-Kakoulidou, A., van der Valk, F., Rekker, R. F., Bijloo, G. J., Zoetemelk, C. E. M., van Hoven, W., van Meeteren-Wālchli, B., van der Gen, A., Mohn, G. R., Buijs, W., Breimer, D. D., Onkenhout, W., de Jong, H. J., Rog, A. A., van Ginneken, C. A. M., Lentjes, E. G. W. M., Bast, A., Savenije-Chapel, E. M., Noordhoek, J., Beld, A. J., Rodrigues de Miranda, J. F., van Ginneken, C. A. M., van der Giesen, W. F., Dröge, J. H. M., Wilting, J., Janssen, L. H. M., van Amsterdam, J. G. C., van Buuren, K. J. H., Wijnne, H. J. A., Nolet, M. R. A., Kremer, J. M. H., Bakker, G., van der Heijden, P. J. C. M., van der Schaar, M. W. G., Bank, C. M. C., Eriks, J. Ch., Gaisser, H. -D., van der Goot, H., Sterk, G. J., Zaagsma, J., Lock, F. M., de Vries, J., Mullink, H., van Bree, L., Redegeld, F. A. M., Grolleman, C. W. J., de Visser, A. C., Wolke, J. G. C., Buchan, P., Burns, J. W.
Publikováno v:
Pharmacy World & Science; December 1982, Vol. 4 Issue: 6 p205-212, 8p
Publikováno v:
Journal of Neural Transmission; Oct1999, Vol. 106 Issue 9/10, p803-818, 16p
Publikováno v:
Journal of Neural Transmission; Jun1999, Vol. 106 Issue 5/6, p409-421, 13p
Autor:
Burm, A. G. L., Van Kleef, J. W., Spierdijk, J., De Boer, A. G., Vermeulen, N. P. E., De Leede, L. G. J., Breimer, D. D.
Publikováno v:
Biopharmaceutics & Drug Disposition; 1988, Vol. 9 Issue 1, p85-95, 11p