Zobrazeno 1 - 10
of 560
pro vyhledávání: '"BRCA2 gene"'
Autor:
Liliana-Georgiana Grigore, Viorica-Elena Radoi, Alexandra Serban, Adina Daniela Mihai, Ileana Stoica
Publikováno v:
Current Issues in Molecular Biology, Vol 46, Iss 5, Pp 4630-4645 (2024)
The objective of this study was to identify and classify the spectrum of mutations found in the BRCA1 and BRCA2 genes associated with breast and ovarian cancer in female patients in Romania. Germline BRCA1 and BRCA2 mutations were investigated in a c
Externí odkaz:
https://doaj.org/article/ebc12e26e0db4ac0912a59aed01a3115
Publikováno v:
Biotechnology & Biotechnological Equipment, Vol 37, Iss 1, Pp 42-48 (2023)
AbstractPublicly available genome-wide data, sequenced from 2730 ancient human samples were analyzed for genetic predisposition to malignancy. The temporal and spatial incidence of risk variants for cancer diseases in ancient genomes was recorded, al
Externí odkaz:
https://doaj.org/article/21e5be0b92d14c0d9ea4cc620da58400
Autor:
Takumi Motohashi, Kazutoshi Isobe, Takahiro Yoshizawa, Yusuke Usui, Hiroshige Shimizu, Muneyuki Sekiya, Shion Miyoshi, Yasuhiko Nakamura, Naohisa Urabe, Susumu Sakamoto, Sakae Homma, Sota Sadamoto, Naobumi Tochigi, Kazuma Kishi
Publikováno v:
Respirology Case Reports, Vol 12, Iss 3, Pp n/a-n/a (2024)
Abstract A 66‐year‐old woman was found to have abnormal shadows on a chest radiograph at a previous hospital 4 years ago, which led to a diagnosis of lung adenocarcinoma, cT2aN1M1b stage IVA. First‐line treatment included carboplatin and paclit
Externí odkaz:
https://doaj.org/article/59796f49e9294fa2a14ea440c1b13db5
Autor:
Marcelo Moreno, Júlia Salles Oliveira, Rafael Canfield Brianese, Douglas Guedes deCastro, Solange Moraes Sanches, Giovana Tardin Torrezan, Karina Miranda Santiago, Marina De Brot, Vladmir Claudio Cordeiro de Lima, Fabiana Baroni Alves Makdissi, Jose Claudio Casali Da Rocha, Vinicius Fernando Calsavara, Dirce Maria Carraro
Publikováno v:
Cancer Medicine, Vol 12, Iss 15, Pp 16129-16141 (2023)
Abstract Background Triple‐negative breast cancer (TNBC) is the neoplasia most associated with BRCA1 germline pathogenic variants (PV) and is more likely to develop metastases than the other breast cancer (BC) subtypes, mainly in the lungs and the
Externí odkaz:
https://doaj.org/article/1f3b0e4ff1c04d46929aef65802f7c1a
Publikováno v:
Breast Cancer: Targets and Therapy, Vol Volume 15, Pp 421-427 (2023)
Nega Berhane,1 Zemene Chekol,1 Aynias Seid1,2 1Department of Medical Biotechnology, Institute of Biotechnology, University of Gondar, Gondar, Ethiopia; 2Department of Biology, Faculty of Natural and Computational Science, Debre-Tabor University, Debr
Externí odkaz:
https://doaj.org/article/adf61ccd1bee4ff7aa06840302c9afbb
Publikováno v:
IJU Case Reports, Vol 5, Iss 6, Pp 489-492 (2022)
Introduction Small‐cell carcinoma of the prostate has a poor prognosis, and treatment options for the refractory disease are unclear. Case presentation A 68‐year‐old man with prostate cancer was referred to our hospital. He was treated with com
Externí odkaz:
https://doaj.org/article/5be2f914addc410e92b2459b033ee40a
Publikováno v:
Egyptian Journal of Medical Human Genetics, Vol 23, Iss 1, Pp 1-9 (2022)
Abstract Background Ovarian cancer (OC) is considered a leading cause of death among women with gynecological malignancies. OC, like breast cancer, shows a familial predisposition to germline mutations in genes BRCA1 or BRCA2, which have proved to pl
Externí odkaz:
https://doaj.org/article/247922d45a754f96991fdba0b6ea46b5
Akademický článek
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Publikováno v:
Journal of V. N. Karazin Kharkiv National University: Series Medicine, Vol 42, Iss 42, Pp 68-76 (2021)
Background: Breast cancer is the most common malignancy in women. In the countries of Central and Eastern Europe founder mutations in the BRCA1 and BRCA2 genes are responsible for a significant proportion of breast cancer cases; however, regional dif
Externí odkaz:
https://doaj.org/article/f3fde417eebb4d10a5d6e490df250b65
Publikováno v:
Revista Científica, Vol 32 (2022)
In non-ovariectomized female dogs, breast tumors are the most frequent neoplasms. There are several points where canine and human breast tumors have clinical and molecular similarities. BRCA1 and BRCA2 genes have been extensively studied in both spec
Externí odkaz:
https://doaj.org/article/d72a684e86394f7ea26562537a7e3ffe