Zobrazeno 1 - 3
of 3
pro vyhledávání: '"BRCA2, Breast cancer type 2 susceptibility protein"'
Publikováno v:
Advanced Drug Delivery Reviews
Graphical abstract
Even given recent advances in nanomedicine development of breast cancer treatment in recent years and promising results in pre-clinical models, cancer nanomedicines often fail at the clinical trial stage. Limitations of conven
Even given recent advances in nanomedicine development of breast cancer treatment in recent years and promising results in pre-clinical models, cancer nanomedicines often fail at the clinical trial stage. Limitations of conven
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76811ce2af0ea0f7b3342230007c3c01
https://doi.org/10.1016/j.addr.2021.03.018
https://doi.org/10.1016/j.addr.2021.03.018
Autor:
Michael A. Trakselis, Shivasankari Gomanthinayagam, David R. McKinzey, Elizabeth P. Jeffries, Kathleen N. Klinzing, Wezley C Griffin, Aleksandar Rajkovic
Publikováno v:
The Journal of Biological Chemistry
The MCM8/9 complex is implicated in aiding fork progression and facilitating homologous recombination (HR) in response to several DNA damage agents. MCM9 itself is an outlier within the MCM family containing a long C-terminal extension (CTE) comprisi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd4d8b4ba7cf75b63f88c53a1b22a8fa
https://doi.org/10.1016/j.jbc.2021.100355
https://doi.org/10.1016/j.jbc.2021.100355
Autor:
Kinga Chmielewska, Żaneta Rygielska, Dominika Tempka, Paulina Tokarz, Magdalena Kluska, László Virág, Agnieszka Robaszkiewicz, Julita Pietrzak
Publikováno v:
Redox Biology
Redox Biology, Vol 15, Iss C, Pp 316-326 (2018)
Redox Biology, Vol 15, Iss C, Pp 316-326 (2018)
Hallmarks of cancer cells include uncontrolled growth and rapid proliferation; thus, cyclin-dependent kinases are a therapeutic target for cancer treatment. Treating non-small lung cancer cells with sublethal concentrations of the CDK4/6 inhibitors,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de6f77c1a1f3468245c3982273c155af
https://pubmed.ncbi.nlm.nih.gov/29306194
https://pubmed.ncbi.nlm.nih.gov/29306194