Zobrazeno 1 - 10
of 528
pro vyhledávání: '"BRCA1, Breast cancer type 1 susceptibility protein"'
Publikováno v:
Senologie - Zeitschrift für Mammadiagnostik und -therapie. 10
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d689010d30a82195e9ac66afe3a02709
https://doi.org/10.1055/s-0033-1347643
https://doi.org/10.1055/s-0033-1347643
Publikováno v:
Advanced Drug Delivery Reviews
Graphical abstract
Even given recent advances in nanomedicine development of breast cancer treatment in recent years and promising results in pre-clinical models, cancer nanomedicines often fail at the clinical trial stage. Limitations of conven
Even given recent advances in nanomedicine development of breast cancer treatment in recent years and promising results in pre-clinical models, cancer nanomedicines often fail at the clinical trial stage. Limitations of conven
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76811ce2af0ea0f7b3342230007c3c01
https://doi.org/10.1016/j.addr.2021.03.018
https://doi.org/10.1016/j.addr.2021.03.018
Autor:
Michael A. Trakselis, Shivasankari Gomanthinayagam, David R. McKinzey, Elizabeth P. Jeffries, Kathleen N. Klinzing, Wezley C Griffin, Aleksandar Rajkovic
Publikováno v:
The Journal of Biological Chemistry
The MCM8/9 complex is implicated in aiding fork progression and facilitating homologous recombination (HR) in response to several DNA damage agents. MCM9 itself is an outlier within the MCM family containing a long C-terminal extension (CTE) comprisi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd4d8b4ba7cf75b63f88c53a1b22a8fa
https://doi.org/10.1016/j.jbc.2021.100355
https://doi.org/10.1016/j.jbc.2021.100355
Publikováno v:
DNA Repair. Apr2017, Vol. 52, p49-58. 10p.
Autor:
Vasily A. Yakovlev
Publikováno v:
Redox Biology
Cells that are not irradiated but are affected by “stress signal factors” released from irradiated cells are called bystander cells. These cells, as well as directly irradiated ones, express DNA damage-related proteins and display excess DNA dama
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f22d39f57664390fa46ffa89e1be29f0
Autor:
Kinga Chmielewska, Żaneta Rygielska, Dominika Tempka, Paulina Tokarz, Magdalena Kluska, László Virág, Agnieszka Robaszkiewicz, Julita Pietrzak
Publikováno v:
Redox Biology
Redox Biology, Vol 15, Iss C, Pp 316-326 (2018)
Redox Biology, Vol 15, Iss C, Pp 316-326 (2018)
Hallmarks of cancer cells include uncontrolled growth and rapid proliferation; thus, cyclin-dependent kinases are a therapeutic target for cancer treatment. Treating non-small lung cancer cells with sublethal concentrations of the CDK4/6 inhibitors,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de6f77c1a1f3468245c3982273c155af
https://pubmed.ncbi.nlm.nih.gov/29306194
https://pubmed.ncbi.nlm.nih.gov/29306194
Publikováno v:
Computational and Structural Biotechnology Journal
Computational and Structural Biotechnology Journal, Vol 14, Iss C, Pp 223-233 (2016)
Computational and Structural Biotechnology Journal, Vol 14, Iss C, Pp 223-233 (2016)
Altered cellular metabolism is a fundamental adaptation of cancer during rapid proliferation as a result of growth factor overstimulation. We review different pathways involving metabolic alterations in cancers including aerobic glycolysis, pentose p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::268eb25358d62f10bdd206de1d1c97d9
https://pubmed.ncbi.nlm.nih.gov/27358718
https://pubmed.ncbi.nlm.nih.gov/27358718
Autor:
Zhu, Chang1,2 (AUTHOR), Liao, Jing-Yu1,2 (AUTHOR), Liu, Yi-Yang1,2 (AUTHOR), Chen, Ze-Yu1,2 (AUTHOR), Chang, Rui-Zhi1,2 (AUTHOR), Chen, Xiao-Ping1,2 (AUTHOR), Zhang, Bi-Xiang1,2 (AUTHOR) bixiangzhang@hust.edu.cn, Liang, Jun-Nan1,2 (AUTHOR) liangjunnan@tjh.tjmu.edu.cn
Publikováno v:
Molecular Cancer. 11/14/2024, Vol. 23 Issue 1, p1-25. 25p.
Autor:
Margarita Maurer, Józefa Węsierska-Gądek, Andrzej Skladanowski, Nora Zulehner, Oxana Komina, Franziska Ferk
Publikováno v:
Biochemical Pharmacology
Graphical abstract
Two cellular proteins encoded by the breast and ovarian cancer type 1 susceptibility (BRCA1 and BRCA2) tumor suppressor genes are essential for DNA integrity and the maintenance of genomic stability. Approximately 5–10% of b
Two cellular proteins encoded by the breast and ovarian cancer type 1 susceptibility (BRCA1 and BRCA2) tumor suppressor genes are essential for DNA integrity and the maintenance of genomic stability. Approximately 5–10% of b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a962aa50acdf9a2d56583ca55fbb3435
https://pubmed.ncbi.nlm.nih.gov/22906755
https://pubmed.ncbi.nlm.nih.gov/22906755
Autor:
Saha, Biki1 (AUTHOR), Pallatt, Sneha1 (AUTHOR), Banerjee, Antara1 (AUTHOR), Banerjee, Abhijit G.2 (AUTHOR), Pathak, Rupak3 (AUTHOR) rpathak@uams.edu, Pathak, Surajit1 (AUTHOR) rpathak@uams.edu
Publikováno v:
Cells (2073-4409). Sep2024, Vol. 13 Issue 18, p1560. 21p.