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Transcriptional profiling of the developing rat ovary following intrauterine exposure to the endocrine disruptors diethylstilbestrol and ketoconazole

Autor: Indusha Kugathas, Hanna K. L. Johansson, Edith Chan Sock Peng, Maryne Toupin, Bertrand Evrard, Thomas A. Darde, Julie Boberg, Monica K. Draskau, Antoine D. Rolland, Séverine Mazaud-Guittot, Frédéric Chalmel, Terje Svingen

Publikováno v: Kugathas, I, Johansson, H K L, Chan Sock Peng, E, Toupin, M, Evrard, B, Darde, T A, Boberg, J, Draskau, M K, Rolland, A D, Mazaud-Guittot, S, Chalmel, F & Svingen, T 2023, ' Transcriptional profiling of the developing rat ovary following intrauterine exposure to the endocrine disruptors diethylstilbestrol and ketoconazole ', Archives of Toxicology, vol. 97, pp. 849-863 . https://doi.org/10.1007/s00204-023-03442-2
Archives of Toxicology
Archives of Toxicology, 2023, 97 (3), pp.849-863. ⟨10.1007/s00204-023-03442-2⟩

Exposure to endocrine-disrupting chemicals (EDCs) during development may cause reproductive disorders in women. Although female reproductive endpoints are assessed in rodent toxicity studies, a concern is that typical endpoints are not sensitive enou

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2dc064d00a0564016fb619e64450e33a
https://orbit.dtu.dk/en/publications/3d1771d2-2852-4992-9796-cc5d695b3671

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Distinct Gene Set Enrichment Profiles in Eosinophilic and Non-Eosinophilic Chronic Rhinosinusitis with Nasal Polyps by Bulk RNA Barcoding and Sequencing

Autor: Takashi Ishino, Sachio Takeno, Kota Takemoto, Kensuke Yamato, Takashi Oda, Manabu Nishida, Yuichiro Horibe, Nobuyuki Chikuie, Takashi Kono, Takayuki Taruya, Takao Hamamoto, Tsutomu Ueda

Publikováno v: International Journal of Molecular Sciences; Volume 23; Issue 10; Pages: 5653

Chronic rhinosinusitis with nasal polyps (CRSwNP) is a chronic inflammatory disease with a high symptom burden, including nasal congestion and smell disorders. This study performed a detailed transcriptomic analysis in CRSwNP classified as eosinophil

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a926db02611c5ffe73bf18afeb46a2b7
https://pubmed.ncbi.nlm.nih.gov/35628459

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Profiling the Atopic Dermatitis Epidermal Transcriptome by Tape Stripping and BRB-seq

Autor: Tu Hu, Tanja Todberg, Daniel Andersen, Niels Banhos Danneskiold-Samsøe, Sofie Boesgaard Neestrup Hansen, Karsten Kristiansen, David Adrian Ewald, Susanne Brix, Joel Correa da Rosa, Ilka Hoof, Lone Skov, Thomas Litman

Publikováno v: International Journal of Molecular Sciences; Volume 23; Issue 11; Pages: 6140
Hu, T, Todberg, T, Andersen, D, Danneskiold-Samsøe, N B, Hansen, S B N, Kristiansen, K, Ewald, D A, Brix, S, da Rosa, J C, Hoof, I, Skov, L & Litman, T 2022, ' Profiling the Atopic Dermatitis Epidermal Transcriptome by Tape Stripping and BRB-seq ', International Journal of Molecular Sciences, vol. 23, no. 11, 6140 . https://doi.org/10.3390/ijms23116140
Hu, T, Todberg, T, Andersen, D, Danneskiold-Samsøe, N B, Hansen, S B N, Kristiansen, K, Ewald, D A, Brix, S, Rosa, J C D, Hoof, I, Skov, L & Litman, T 2022, ' Profiling the Atopic Dermatitis Epidermal Transcriptome by Tape Stripping and BRB-seq ', International Journal of Molecular Sciences, vol. 23, no. 11, 6140 . https://doi.org/10.3390/ijms23116140

Tape stripping is a non-invasive skin sampling technique, which has recently gained use for the study of the transcriptome of atopic dermatitis (AD), a common inflammatory skin disorder characterized by a defective epidermal barrier and perturbated i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bec346b14f78b1f04fd1d13f4d499b33
https://pubmed.ncbi.nlm.nih.gov/35682818

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The anti-androgenic fungicide triticonazole induces region-specific transcriptional changes in the developing rat perineum and phallus

Autor: Monica Kam Draskau, Camilla Lindgren Schwartz, Bertrand Evrard, Aurélie Lardenois, Andrew Pask, Frédéric Chalmel, Terje Svingen

Publikováno v: Draskau, M K, Schwartz, C L, Evrard, B, Lardenois, A, Pask, A, Chalmel, F & Svingen, T 2022, ' The anti-androgenic fungicide triticonazole induces region-specific transcriptional changes in the developing rat perineum and phallus ', Chemosphere, vol. 308, 136346 . https://doi.org/10.1016/j.chemosphere.2022.136346
Chemosphere
Chemosphere, 2022, 308 (Pt 2), pp.136346. ⟨10.1016/j.chemosphere.2022.136346⟩

International audience; Intrauterine exposure to endocrine disrupting chemicals can interfere with male reproductive development. This can lead to male reproductive disorders such as hypospadias, cryptorchidism and reduced fertility, as well as short

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa38a520c2c1d1bbcfc21a80add54f3c
https://orbit.dtu.dk/en/publications/d87692f1-9b13-46ea-b2f8-4a6c876d06ff

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