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ChemInform Abstract: Nonprostanoid Prostacyclin Mimetics. Part 4. Derivatives of 2-(3-(2-(4, 5-Diphenyl-2-oxazolyl)ethyl)phenoxy)acetic Acid Substituted α to the Oxazole Ring.

Autor: MEANWELL, N. A., ROSENFELD, M. J., WRIGHT, J. J. K., BRASSARD, C. L., BUCHANAN, J. O., FEDERICI, M. E., FLEMING, J. S., GAMBERDELLA, M., HARTL, K. S., ZAVOICO, G. B., SEILER, S. M.

Publikováno v: ChemInform; Jun1994, Vol. 25 Issue 25, pno-no, 1p

[3-[4-(4,5-Diphenyl-2-oxazolyl)-5-oxazolyl]phenoxy]acetic acid (BMY 45778) is a potent non-prostanoid prostacyclin partial agonist: effects on platelet aggregation, adenylyl cyclase, cAMP levels, protein kinase, and iloprost binding.

Autor: Seiler SM; Department of Cardiovascular, Bristol-Myers Squibb Pharmaceutical Research Institute Wallingford, CT, USA. Seiler_Steven_M.PRILVMS3@msmail.bms.com, Brassard CL, Federici ME, Romine J, Meanwell NA

Publikováno v: Prostaglandins [Prostaglandins] 1997 Jan; Vol. 53 (1), pp. 21-35.

Nonprostanoid prostacyclin mimetics. 4. Derivatives of 2-[3-[2-(4,5-diphenyl-2-oxazolyl)ethyl]phenoxy]acetic acid substituted alpha to the oxazole ring.

Autor: Meanwell NA; Division of Chemistry, Bristol-Myers Squibb Pharmaceutical Research Institute, Wallingford, Connecticut 06492-7660., Rosenfeld MJ, Wright JJ, Brassard CL, Buchanan JO, Federici ME, Fleming JS, Gamberdella M, Hartl KS, Zavoico GB, et. al.

Publikováno v: Journal of medicinal chemistry [J Med Chem] 1993 Nov 26; Vol. 36 (24), pp. 3871-83.

Nonprostanoid prostacyclin mimetics. 2. 4,5-Diphenyloxazole derivatives.

Autor: Meanwell NA; Department of Cardiovascular Chemistry, Bristol-Myers Squibb Pharmaceutical Research Institute, Wallingford, Connecticut 06492., Rosenfeld MJ, Trehan AK, Wright JJ, Brassard CL, Buchanan JO, Federici ME, Fleming JS, Gamberdella M, Zavoico GB, et. al.

Publikováno v: Journal of medicinal chemistry [J Med Chem] 1992 Sep 18; Vol. 35 (19), pp. 3483-97.