High-Content Analysis Provides Mechanistic Insights into the Testicular Toxicity of Bisphenol A and Selected Analogues in Mouse Spermatogonial Cells

Autor: Marie Claude Hofmann, Kevin Shengyang Yu, Xiaozhong Yu, Shenxuan Liang, Lei Yin

Bisphenol A (BPA), an endocrine-disrupting compound, was found to be a testicular toxicant in animal models. Bisphenol S (BPS), bisphenol AF (BPAF), and tetrabromobisphenol A (TBBPA) were recently introduced to the market as alternatives to BPA. Howe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad6fe3adb16e411d6975b4bb2ead59ba
https://europepmc.org/articles/PMC5216646/

Evaluation of low doses BPA-induced perturbation of glycemia by toxicogenomics points to a primary role of pancreatic islets and to the mechanism of toxicity

Autor: Immacolata Porreca, Concetta Ambrosino, Fulvio D'Angelo, M De Felice, Danila Cuomo, Massimo Mallardo, Emanuele Carchia, P. J. Almeida, Michele Ceccarelli

Publikováno v: Cell death and disease 6 (2015). doi:10.1038/cddis.2015.319
info:cnr-pdr/source/autori:Carchia, E.; Porreca, I.; Almeida, P. J.; D'Angelo, F.; Cuomo, D.; Ceccarelli, M.; De Felice, M.; Mallardo, M.; Ambrosino, C./titolo:Evaluation of low doses BPA-induced perturbation of glycemia by toxicogenomics points to a primary role of pancreatic islets and to the mechanism of toxicity/doi:10.1038%2Fcddis.2015.319/rivista:Cell death and disease/anno:2015/pagina_da:/pagina_a:/intervallo_pagine:/volume:6
Cell Death & Disease

Epidemiologic and experimental studies have associated changes of blood glucose homeostasis to Bisphenol A (BPA) exposure. We took a toxicogenomic approach to investigate the mechanisms of low-dose (1 × 10−9M) BPA toxicity in ex vivo cultures of p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79834726becb7cb706928732d259596f

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