Zobrazeno 1 - 10
of 55
pro vyhledávání: '"BP-897"'
Dopamine D3 receptor binding of18F-fallypride: Evaluation usingin vitroandin vivoPET imaging studies
Autor:
Angela T. Hoang, Cristian Constantinescu, Min-Liang Pan, Jogeshwar Mukherjee, Taleen Jerjian, Divya Majji
Publikováno v:
Synapse. 69:577-591
Identification of dopamine D3 receptors (D3R) in vivo is important to understand several brain functions related to addiction. The goal of this work was to identify D3R binding of the dopamine D2 receptor (D2R)/D3R imaging agent, (18)F-fallypride. Br
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6e33b0bbd3fce9a04b8e3e3be4029f88
https://doi.org/10.1002/syn.21867
https://doi.org/10.1002/syn.21867
Autor:
James Henry Woods, David K. Grandy, Peter Grundt, Ming Xu, Jonathan L. Katz, Noel M. Paul, Gregory T. Collins, Amy Hauck Newman, Su Min Li
Publikováno v:
Behavioural Pharmacology. 21:171-181
Dopaminergic (DA) agonist-induced yawning in rats seems to be mediated by DA D3 receptors, and low doses of several DA agonists decrease locomotor activity, an effect attributed to presynaptic D2 receptors. Effects of several DA agonists on yawning a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d05b41a24aa080a70c0a26ba3753766
https://doi.org/10.1097/fbp.0b013e32833a5c68
https://doi.org/10.1097/fbp.0b013e32833a5c68
Autor:
Mette Skinbjerg, Sami S. Zoghbi, David R. Sibley, Christer Halldin, Jinsoo Hong, Nicholas Seneca, Victor W. Pike, Robert B. Innis, Jeih-San Liow
Publikováno v:
Synapse. 62:756-763
Estimates of dopamine D(2/3) receptor occupancy by endogenous dopamine using positron emission tomography (PET) in animals have varied almost threefold. This variability may have been caused by incomplete depletion of dopamine or by the use of antago
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52e51744f7cea2394bb385a821d2ae10
https://doi.org/10.1002/syn.20549
https://doi.org/10.1002/syn.20549
Publikováno v:
Neurotoxicity Research. 14:57-69
Dopamine D(3) receptors (Drd3) have been implicated in the control of responding by drug-related conditioned incentive stimuli. We review recent studies of the effects of Drd3 antagonists or partial agonists on the control of self-administration of i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4faa2a58d3da425b0ede18489b8f9b9
https://doi.org/10.1007/bf03033575
https://doi.org/10.1007/bf03033575
Publikováno v:
European Journal of Pharmacology. 579:167-176
There has been considerable interest in the role of dopamine D 3 receptors in appetitive conditioning but few studies have examined their role in aversive conditioning. The present study examined the effect of the dopamine D 3 receptor-preferring par
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9721c85093dffb6e7bc73c16152a88dd
https://doi.org/10.1016/j.ejphar.2007.10.011
https://doi.org/10.1016/j.ejphar.2007.10.011
Publikováno v:
European Journal of Pharmacology. 573:116-123
Cocaine-paired stimuli can suppress food-reinforced operant behavior in rats, providing an animal model of conditioned drug effects. To study the neuropharmacological basis of this phenomenon, we examined the effects of various dopamine receptor anta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::823414af3d98f9ce45fc75520e20b4e9
https://doi.org/10.1016/j.ejphar.2007.06.037
https://doi.org/10.1016/j.ejphar.2007.06.037
Publikováno v:
Psychopharmacology. 193:475-486
Rationale Maternal deprivation and handling can lead to a vulnerabilitytoopiatedependence.However,theinvolvement of the dopamine D3 receptors has not been investigated. Objectives This study analysed the effects of a selective partial D3 receptor ago
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa8735189640a366b66a645c70f48f20
https://doi.org/10.1007/s00213-007-0789-9
https://doi.org/10.1007/s00213-007-0789-9
Publikováno v:
Expert Opinion on Investigational Drugs. 16:45-57
This review considers the potential use of the dopamine D(3) receptor (DRD3) as a novel therapeutic target for the treatment of tobacco dependence. Among the 5 dopamine receptors identified, the DRD3 is located in the nucleus accumbens, ventral tegme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81c582d32d21b3a5af3e709615df4915
https://doi.org/10.1517/13543784.16.1.45
https://doi.org/10.1517/13543784.16.1.45
Autor:
Valentina Vengeliene, Stephanie Perreau-Lenz, Fernando Leonardi-Essmann, Gerhard Gross, Karla Drescher, Rainer Spanagel, Peter J. Gebicke-Haerter
Publikováno v:
The FASEB Journal. 20:2223-2233
Our study aimed to identify new candidate genes, which might be involved in alcohol craving and relapse. To find changes in gene expression after long-term alcohol consumption, we studied gene expression profiles in the striatal dopamine system by us
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66fffa4dd35a0ce86f696419adb28699
https://doi.org/10.1096/fj.06-6110com
https://doi.org/10.1096/fj.06-6110com
Autor:
B. F. Cox, F. J. Garcia-Ladona
Publikováno v:
CNS Drug Reviews. 9:141-158
BP 897 is a potent (K(i) = 0.92 nM) dopamine D(3) receptor compound developed for the treatment of cocaine abuse and craving. BP 897 has a high selectivity for the dopamine D(3) versus D(2) receptors (70-fold) and a moderate affinity for 5-HT(1A) rec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad2c7e2fc7751e3958d106a5aefdd0b2
https://doi.org/10.1111/j.1527-3458.2003.tb00246.x
https://doi.org/10.1111/j.1527-3458.2003.tb00246.x