Zobrazeno 1 - 10
of 713
pro vyhledávání: '"BONE MICROENVIRONMENT"'
Publikováno v:
Molecular Cancer, Vol 23, Iss 1, Pp 1-32 (2024)
Abstract Malignant bone tumors, which are difficult to treat with current clinical strategies, originate from bone tissues and can be classified into primary and secondary types. Due to the specificity of the bone microenvironment, the results of tra
Externí odkaz:
https://doaj.org/article/f366187607574eda89453039d54c9390
Autor:
Zengfeng Xin, Luying Qin, Yang Tang, Siyu Guo, Fangfang Li, Yuan Fang, Gege Li, Yihan Yao, Binbin Zheng, Bicheng Zhang, Dang Wu, Jie Xiao, Chao Ni, Qichun Wei, Ting Zhang
Publikováno v:
Cancer Communications, Vol 44, Iss 9, Pp 967-991 (2024)
Abstract Bone is a common organ affected by metastasis in various advanced cancers, including lung, breast, prostate, colorectal, and melanoma. Once a patient is diagnosed with bone metastasis, the patient's quality of life and overall survival are s
Externí odkaz:
https://doaj.org/article/6e54616f16104a7da68d847ead7839cf
Publikováno v:
Smart Materials in Medicine, Vol 5, Iss 3, Pp 359-372 (2024)
Diabetes mellitus (DM) is a chronic metabolic disorder that can affect the balance of bone metabolism and bone microenvironment, leading to impaired fracture healing. There are several underlying mechanisms which contributing to the impaired diabetic
Externí odkaz:
https://doaj.org/article/0d1822e974694e71964f8c32b14ea923
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 12 (2024)
Bone defects can arise from trauma or pathological factors, resulting in compromised bone integrity and the loss or absence of bone tissue. As we are all aware, repairing bone defects is a core problem in bone tissue engineering. While minor bone def
Externí odkaz:
https://doaj.org/article/a0f3f8f989e2474390af566482036d75
Autor:
Raquel Cabrera-Pérez, Alexis Ràfols-Mitjans, Ángela Roig-Molina, Silvia Beltramone, Joaquim Vives, Laura Batlle-Morera
Publikováno v:
Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-12 (2023)
Abstract Background Wharton’s Jelly (WJ) Mesenchymal Stromal Cells (MSC) have emerged as an attractive allogeneic therapy for a number of indications, except for bone-related conditions requiring new tissue formation. This may be explained by the a
Externí odkaz:
https://doaj.org/article/f7f4a9c490234a9994225d30f52e38f2
Publikováno v:
Cancer Management and Research, Vol Volume 15, Pp 1323-1337 (2023)
Yi-Ming Gao,1 Yan Pei,1 Fei-Fei Zhao,2 Ling Wang1 1Department of Orthopedic Oncology, The Third Hospital of Hebei Medical University, Shijiazhuang, Hebei, People’s Republic of China; 2Department of Orthopedics, The Fourth Hospital of Hebei Medical
Externí odkaz:
https://doaj.org/article/2cd3f9b819ce4be4ad03ee788aacd4a2
Publikováno v:
Frontiers in Endocrinology, Vol 15 (2024)
With the development of social population ageing, bone fracture has become a global public health problem due to its high morbidity, disability and mortality. Fracture healing is a complex phenomenon involving the coordinated participation of immigra
Externí odkaz:
https://doaj.org/article/a98039c8a5234827927b0736c32761cc
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2024)
Evidence demonstrated that bones, liver, and lungs are the most common metastasis sites in some human malignancies, especially in prostate and breast cancers. Bone is the third most frequent target for spreading tumor cells among these organs and tis
Externí odkaz:
https://doaj.org/article/78b954f882f04992bdb39369aeee971e
Autor:
Zhichao Hao, Lin Ren, Zhen Zhang, Zaiwu Yang, Shujie Wu, Gen Liu, Bin Cheng, Jun Wu, Juan Xia
Publikováno v:
Bioactive Materials, Vol 23, Iss , Pp 206-222 (2023)
Recent evidence highlights multifaceted biological needs to recapitulate the bone microenvironment for bone regeneration. Neurotization has great potential for realizing multi-system modulations in bone tissue engineering (BTE). However, a neural str
Externí odkaz:
https://doaj.org/article/69a80e97443741bb855014c5b3c363b9
Publikováno v:
Biomedicines, Vol 12, Iss 5, p 1075 (2024)
The phenomenon of bone metastases presents a significant challenge within the context of advanced cancer treatments, particularly pertaining to breast, prostate, and lung cancers. These metastatic occurrences stem from the dissemination of cancerous
Externí odkaz:
https://doaj.org/article/29f79f43724f46f7aec9461081abcadb