Zobrazeno 1 - 10
of 37
pro vyhledávání: '"BNOS 2021 Abstracts"'
Publikováno v:
Neuro Oncol
Aims Glioblastoma (GBM) is a treatment refractory cancer of extreme unmet need which exhibits treatment resistance due to a subpopulation of GBM cancer stem cells which have constitutive DNA damage response activation driven by elevated replication s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e85993a7408909297415f97e717a8ccf
https://europepmc.org/articles/PMC8517858/
https://europepmc.org/articles/PMC8517858/
Autor:
Michael D. Jenkinson, Georgios Solomou, Keyoumars Ashkan, Kathrin Whitehouse, Puneet Plaha, Rory J Piper, Daniel M Fountain, Danyal Z. Khan, Stephen J. Price, Colin Watts, Angelos G. Kolias, Ali Gharooni, Melissa Gough
Publikováno v:
Neuro Oncol
Aims Extent of resection is associated with better survival in patients with glioblastoma. Numerous surgical adjuncts can be used to achieve maximal safe resection - including fluorescence-guidance with 5-aminolevulinic acid (5-ALA), neuronavigation,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96e369bc4d3ab0f2e4e77ec16ad72f89
https://europepmc.org/articles/PMC8517866/
https://europepmc.org/articles/PMC8517866/
Publikováno v:
Neuro Oncol
Aims Brain Tumour Related Epilepsy (BTRE) has a significant impact on Quality of Life with implications for driving, employment and social and domestic activities. Management of BTRE is complex due to the higher incidence of pharmacoresistance and th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7163662dd79253e405710178d576b56
https://europepmc.org/articles/PMC8517889/
https://europepmc.org/articles/PMC8517889/
Autor:
Nigel Davies, Robert Flintham, Vinay Duddalwar, Andrew C. Peet, Jinfeng Zhan, Markand Patel, Vijay Sawlani, Paul Sanghera, Kal Natarajan, James T. Grist
Publikováno v:
Neuro Oncol
Aims Treatment response assessment in glioblastoma is challenging. Patients routinely undergo conventional magnetic resonance imaging (MRI), but it has a low diagnostic accuracy for distinguishing between true progression (tPD) and pseudoprogression
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b07afd3a3a4da1afeaad39a681b9272
https://europepmc.org/articles/PMC8517861/
https://europepmc.org/articles/PMC8517861/
Publikováno v:
Neuro Oncol
Aims Glioblastoma (GBM) is currently an incurable malignancy with a very poor prognosis for the majority of patients. Many patients undergo debulking surgery, radiotherapy and chemotherapy however therapeutic options are limited, and this can lead to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2678e4d6d7689a8da78a50aa1a14d534
https://europepmc.org/articles/PMC8517860/
https://europepmc.org/articles/PMC8517860/
Publikováno v:
Neuro Oncol
Aims Molecular profiling is increasingly used in the diagnosis of CNS and non-CNS neoplasms. More than a quarter of all soft tissue tumours are characterized by specific recurrent chromosomal translocations which can be used as molecular signatures.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6719e04720cbb07a1932585e1ac3153
https://europepmc.org/articles/PMC8517870/
https://europepmc.org/articles/PMC8517870/
Autor:
Heidi M. Feldman, Gerald A. Grant, Kristian Aquilina, Chris A. Clark, Katie Travis, Rashad Jabarkheel, Kshitij Mankad, Lisa Bruckert, Kristen W. Yeom, Sebastian Toescu, Derek Yecies
Publikováno v:
Neuro Oncol
Aims Cerebellar mutism syndrome occurs in 25% of children following resection of posterior fossa tumours. Characterised by mutism, emotional lability and cerebellar motor signs, the syndrome is usually reversible over weeks to months. Its pathophysio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de23194fa5f1cd1ac972bd937c0f6a13
https://europepmc.org/articles/PMC8517865/
https://europepmc.org/articles/PMC8517865/
Autor:
Peter Buckle, Margaret E O’Hara, Colin Watts, Helen Benghiat, Claire Goddard, Frederick Berki, Victoria Wykes, William Garratt, Elizabeth Walker
Publikováno v:
Neuro Oncol
Aims Every year, the Queen Elizabeth Hospital Birmingham (QEHB) neuro-oncology team review over 2000 individuals with brain tumour. Patient and public involvement (PPI) has been fragmented to date. Initially we invited two patient advocates and a cor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5050c1bd238c0520bcafdaeaab63d457
https://europepmc.org/articles/PMC8517875/
https://europepmc.org/articles/PMC8517875/
Publikováno v:
Neuro Oncol
Aims Glioblastoma multiforme (GBM) is a devastating disease with notoriously poor survival. Studies examining survival in patients given best supportive care (BSC) are few and far between. All patients harbouring brain tumours referred to the Neuro-o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e400ad57d0813ff1f2bc3b0c18a529c9
https://europepmc.org/articles/PMC8517871/
https://europepmc.org/articles/PMC8517871/
Autor:
Evyn Woodhouse, Liyam Laraba, David Parkinson, Alison C. Lloyd, Charlotte Lespade, Marie Srotyr
Publikováno v:
Neuro Oncol
Aims Previous work has shown that increased numbers of macrophages are associated with more rapid schwannoma tumour growth and we are interested in signals that control entry of macrophages and other immune cells into these tumours. Activation of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4dc43611f335d25ad42b3f2ea2f55f38
https://europepmc.org/articles/PMC8517855/
https://europepmc.org/articles/PMC8517855/