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pro vyhledávání: '"BMS-754807"'
Autor:
Hassan, Md Sazzad1,2 (AUTHOR) hassansa@iu.edu, Johnson, Chloe3 (AUTHOR), Ponna, Saisantosh3 (AUTHOR), Scofield, Dimitri4 (AUTHOR), Awasthi, Niranjan1,2 (AUTHOR), von Holzen, Urs1,2,5,6 (AUTHOR)
Publikováno v:
Cancers. Sep2024, Vol. 16 Issue 18, p3175. 18p.
Akademický článek
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Autor:
Ho, Alyssa N.1 (AUTHOR), Kiesel, Violet A.1 (AUTHOR), Gates, Claire E.1,2 (AUTHOR), Brosnan, Bennett H.1 (AUTHOR), Connelly, Scott P.1 (AUTHOR), Glenny, Elaine M.1 (AUTHOR), Cozzo, Alyssa J.1 (AUTHOR), Hursting, Stephen D.1,3,4 (AUTHOR), Coleman, Michael Francis1,3 (AUTHOR) mcoleman@unc.edu
Publikováno v:
Cells (2073-4409). May2024, Vol. 13 Issue 10, p806. 16p.
Autor:
Franks, S. Elizabeth1, Jones, Robert A.1, Briah, Ritesh1, Murray, Payton1, Moorehead, Roger A.1 rmoorehe@uoguelph.ca
Publikováno v:
BMC Research Notes. 3/1/2016, Vol. 9, p1-12. 12p. 3 Charts, 5 Graphs.
Akademický článek
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PDF file - 43K, Effects of gemcitabine and BMS-754807 therapy on mouse body weight. Nude mice were subcutaneously injected with AsPC-1 cell (0.75 x 106). Fourteen days after tumor cell injection, therapy was started with gemcitabine and BMS-754807 fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49d1d4e82968fced1578f9f0827885ce
https://doi.org/10.1158/1535-7163.22496562.v1
https://doi.org/10.1158/1535-7163.22496562.v1
Autor:
Joan M. Carboni, Jeffrey Jackson, Friedrich G. Finckenstein, Tai W. Wong, Rolf-Peter Ryseck, Craig Fairchild, Zhenhao Qi, Dharmesh Patel, John Cogswell, Warren Hurlburt, Karen A. Reeves, Stephen Hillerman, Ann Greer, Han Chang, Fei Huang
Supplementary Tables S1-S4. Supplementary Table S1: Association of gene mutations, IRS2 copy number gain, and gene expression level with in vitro sensitivity to BMS-754807 in 60 CRC cell lines. Supplementary Table S2: The relationship between KRAS, B
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::faf361093d6982b4e2b58d163680e344
https://doi.org/10.1158/1535-7163.22503652.v1
https://doi.org/10.1158/1535-7163.22503652.v1
Gemcitabine has limited clinical benefits in pancreatic ductal adenocarcinoma (PDAC). Insulin-like growth factor (IGF) signaling proteins are frequently overexpressed in PDAC. The therapeutic potential of BMS-754807, a small-molecule inhibitor of IGF
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::818f33a0bd9ba3885ee72fd0014f89bc
https://doi.org/10.1158/1535-7163.c.6535323.v1
https://doi.org/10.1158/1535-7163.c.6535323.v1
Autor:
Marco M. Gottardis, Ricardo M. Attar, Robert Kramer, Dolatrai Vyas, George Trainor, Aixin Li, Krista Menard, Lorell Discenza, Cliff Chen, Janet Dell-John, Glenn H. Cantor, Carolyn Cao, Stephen Hillerman, Warren Hurlburt, Ann Greer, Francis Lee, Zheng Yang, Mark Wittman, Joan M. Carboni
BMS-754807 is a potent and reversible inhibitor of the insulin-like growth factor 1 receptor/insulin receptor family kinases (Ki, in vitro, including mesenchymal (Ewing's, rhabdomyosarcoma, neuroblastoma, and liposarcoma), epithelial (breast, lung, p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::afc63230107c1e05a299e1da8aaf1d21
https://doi.org/10.1158/1535-7163.c.6531836.v1
https://doi.org/10.1158/1535-7163.c.6531836.v1
Autor:
Joan M. Carboni, Marco M. Gottardis, Friedrich Graf Finckenstein, Joseph Fargnoli, Han Chang, Stephen Hillerman, Karen A. Reeves, Ann Greer, Warren Hurlburt, Fei Huang
Agents targeting insulin-like growth factor-I receptor (IGF-IR), including antibodies and small-molecule inhibitors, are currently in clinical development for the treatment of cancers including sarcoma. However, development of resistance is a common
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9df3de15f1f66352b33605d244cb2df4
https://doi.org/10.1158/0008-5472.c.6501168
https://doi.org/10.1158/0008-5472.c.6501168