Výsledky vyhledávání - "BMPs, bone morphogenetic proteins"

Transforming growth factor β latency: A mechanism of cytokine storage and signalling regulation in liver homeostasis and diseaseKey points

Autor: S Wang, Frederik Link, Weiguo Fan, Yujia Li, Steven Dooley

Publikováno v: JHEP Reports, Vol 4, Iss 2, Pp 100397-(2022)
JHEP Reports

TGF-β is a very strong effector in the liver, involved in a plethora of processes initiated upon liver injury. TGF-β affects parenchymal, non-parenchymal, and inflammatory cells in a highly context-dependent manner. Its bioavailability is critical

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42c6922f0d78109475d83c4ca70e310f
http://www.sciencedirect.com/science/article/pii/S2589555921001737

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Responses of oral-microflora-exposed dental pulp to capping with a triple antibiotic paste or calcium hydroxide cement in mouse molars

Autor: Hiroko Ida-Yonemochi, Takuichi Sato, Hayato Ohshima, Junko Matsuyama, Angela Quispe-Salcedo

Publikováno v: Regenerative Therapy
Regenerative Therapy, Vol 15, Iss, Pp 216-225 (2020)

Introduction Responses of oral-microflora-exposed dental pulp to a triple antibiotic paste (TAP), a mixture of ciprofloxacin, metronidazole, and minocycline in ointment with macrogol and propylene glycol, remain to be fully clarified at the cellular

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8de7c16a93b33859f7c5b39aab179c6f
https://pubmed.ncbi.nlm.nih.gov/33426222

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c-Met expression in renal cell carcinoma with bone metastases

Autor: Sandra Casimiro, Inês Gomes, Isabel Fernandes, Luis Costa, R. Paiva

Publikováno v: Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Journal of Bone Oncology, Vol 25, Iss, Pp 100315-(2020)
Journal of Bone Oncology

© 2020 The Author(s). Published by Elsevier GmbH. This is an open access article under the CC BY-NC-ND license. (http://creativecommons.org/licenses/BY-NC-ND/4.0/)
Hepatocyte growth factor (HGF)/c-Met pathway is implicated in embryogenesis and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40f9006cf780943817f32d88292f26bb

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Nrg4 promotes fuel oxidation and a healthy adipokine profile to ameliorate diet-induced metabolic disorders

Autor: Liang Guo, Tariq R. Altamimi, Dae Young Jung, Peng Zhang, Xu Yun Zhao, Zhimin Chen, Guoxiao Wang, Jiandie D. Lin, Jason K. Kim, Sara L. Ma, Chun-Rui Hu, Gary D. Lopaschuk, Hyekyung Ha, Ji-Xin Cheng

Publikováno v: Molecular Metabolism, Vol 6, Iss 8, Pp 863-872 (2017)
Molecular Metabolism

Objective Brown and white adipose tissue exerts pleiotropic effects on systemic energy metabolism in part by releasing endocrine factors. Neuregulin 4 (Nrg4) was recently identified as a brown fat-enriched secreted factor that ameliorates diet-induce

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17178f9bd051472d903dcb2d2c5cc3fd
https://doi.org/10.1016/j.molmet.2017.03.016

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Metastatic bone disease: Pathogenesis and therapeutic options

Autor: Janet E. Brown, Stella D'Oronzo, Francesco Silvestris, Robert E. Coleman

Publikováno v: Journal of Bone Oncology, Vol 15, Iss, Pp-(2019)
Journal of Bone Oncology

Highlights • Bone metastases negatively impact on patients’ quality of life (QoL). • Skeletal related events have a detrimental effect on both QoL and survival. • Both local and systemic treatments are often required to manage bone metastases

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::800cf502ba8951ee91fa265eeba1e16b
http://www.sciencedirect.com/science/article/pii/S2212137418302586

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New bone-like tissue formation in calcific tendinopathy: A case report

Autor: Izuru Kitajima, Tatsuya Suwabe, Naoki Sawa, Kazuya Isawa, Masaki Hatano, Yoshihumi Ubara, Masaki Nakamura, Yutaka Hirota, Seizo Yamamoto, Junichi Hoshino

Publikováno v: Bone Reports
Bone Reports, Vol 14, Iss, Pp 101062-(2021)

Currently, the pathogenesis of nontraumatic heterotopic ossification (HO), e.g., bone-like tissue in calcific tendinopathy remains unclear. Here, we report a 75-year-old, right-handed Japanese woman who had been on hemodialysis for 3 years and was ad

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb5b57024f4d8b2ff839a3b7d9aeaf31
https://doi.org/10.1016/j.bonr.2021.101062

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Astrocytes and microglia in neurodegenerative diseases: Lessons from human in vitro models

Autor: Hannah Franklin, Benjamin E. Clarke, Rickie Patani

Publikováno v: Progress in Neurobiology

Highlights • Astrocytes and microglia key fulfil homeostatic and immune functions in the CNS. • Dysfunction of these cell types is implicated in neurodegenerative diseases. • Understanding cellular autonomy and early pathogenic changes is a key

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d83043c7ec4a553f7a3c71f8be5acb59
https://doi.org/10.1016/j.pneurobio.2020.101973

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The role of biomarkers in the management of bone-homing malignancies

Autor: Janet E. Brown, Robert E. Coleman, Stella D'Oronzo

Publikováno v: Journal of Bone Oncology, Vol 9, Iss, Pp 1-9 (2017)
Journal of Bone Oncology

Bone represents a common site of metastasis from several solid tumours, including breast, prostate and lung malignancies. The onset of bone metastases (BM) is associated not only with serious skeletal complications, but also shortened overall surviva

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::252a04c31673cc391f0309675ad5099e
https://eprints.whiterose.ac.uk/122151/1/1-s2.0-S2212137417300775-main.pdf

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ABCC6 deficiency is associated with activation of BMP signaling in liver and kidney

Autor: Yucheng Yao, Aldons J. Lusis, Pierre J. Guihard, Ana M. Blazquez-Medela, Jiayi Yao, Kristina I. Boström, Medet Jumabay

Publikováno v: FEBS Open Bio
FEBS Open Bio, Vol 5, Iss 1, Pp 257-263 (2015)

Highlights • ABCC6 deficiency stimulates BMP signaling in multiple organs. • ABCC6 deficiency causes tissue-specific induction of BMP-related genes. • Tissue-specific targeting of BMP signaling may be needed in ABCC deficiency.
Mutations i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc696f2558e91dec8cdf040104736ef8
https://pubmed.ncbi.nlm.nih.gov/25893161

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Dissertation/ Thesis

Implication des Bone Morphogenetic Proteins (BMPs) hypophysaires dans la régulation de la synthèse et de la libération de l'hormone folliculo-stimulante (FSH) ?

Autor: Sallon, Céline

Chez la brebis, les BMPs inhibent la synthèse et la libération de FSH. La détection des ARNm de certaines BMPs dans l’hypophyse et de leurs récepteurs sur les cellules gonadotropes suggère une action paracrine/autocrine des BMPs sur la product

Externí odkaz: http://www.theses.fr/2010TOUR4040

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